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Protein
Submitted name:

Voltage-dependent L-type calcium channel subunit alpha-1F

Gene

Cacna1f

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCalcium channelUniRule annotation, Ion channel, Voltage-gated channelUniRule annotation
Biological processCalcium transport, Ion transport, Transport
LigandCalcium

Enzyme and pathway databases

ReactomeiR-MMU-5576892 Phase 0 - rapid depolarisation
R-MMU-5576893 Phase 2 - plateau phase

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-dependent L-type calcium channel subunit alpha-1FImported
Gene namesi
Name:Cacna1fImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1859639 Cacna1f

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei52 – 70HelicalSequence analysisAdd BLAST19
Transmembranei144 – 167HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000031142
ExpressionAtlasiB1AVA5 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 177Ion_transInterPro annotationAdd BLAST164
Domaini179 – 229GPHHInterPro annotationAdd BLAST51

Sequence similaritiesi

Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2301 Eukaryota
ENOG410XNP6 LUCA
GeneTreeiENSGT00830000128247

Family and domain databases

InterProiView protein in InterPro
IPR031649 GPHH_dom
IPR005821 Ion_trans_dom
IPR030157 VDCC_L_a1F
IPR002077 VDCCAlpha1
PANTHERiPTHR10037:SF184 PTHR10037:SF184, 1 hit
PfamiView protein in Pfam
PF16905 GPHH, 1 hit
PF00520 Ion_trans, 1 hit
PRINTSiPR00167 CACHANNEL

Sequencei

Sequence statusi: Fragment.

B1AVA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGGHLGESS EDSSRISITF FRLFRVMRLV KLLSKGEGIR TLLWTFIKSF
60 70 80 90 100
QALPYVALLI AMIFFIYAVI GMQMFGKVAL QDGTQINRNN NFQTFPQAVL
110 120 130 140 150
LLFRCATGEA WQEIMLASLP GNRCDPESDF GPGEEFTCGS SFAIVYFISF
160 170 180 190 200
FMLCAFLIIN LFVAVIMDNF DYLTRDWSIL GPHHLDEFKR IWSEYDPGAK
210 220
GRIKHLDVVA LLRRIQPPLG FGKLCPHRV
Length:229
Mass (Da):26,076
Last modified:October 5, 2016 - v8
Checksum:i59A1D759582AD70F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei229Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL672231 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000128628; ENSMUSP00000119207; ENSMUSG00000031142

Similar proteinsi

Entry informationi

Entry nameiB1AVA5_MOUSE
AccessioniPrimary (citable) accession number: B1AVA5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: October 5, 2016
Last modified: March 28, 2018
This is version 79 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health