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B1AVA4

- B1AVA4_MOUSE

UniProt

B1AVA4 - B1AVA4_MOUSE

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Protein
Submitted name:

Voltage-dependent L-type calcium channel subunit alpha-1F

Gene

Cacna1f

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. high voltage-gated calcium channel activity Source: RefGenome
  2. voltage-gated calcium channel activity Source: MGI

GO - Biological processi

  1. axonogenesis Source: MGI
  2. calcium ion import Source: RefGenome
  3. cellular calcium ion homeostasis Source: MGI
  4. dendrite morphogenesis Source: MGI
  5. membrane depolarization during action potential Source: RefGenome
  6. retina development in camera-type eye Source: MGI
  7. visual perception Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Calcium channelUniRule annotation, Ion channel, Voltage-gated channelUniRule annotationSAAS annotation

Keywords - Biological processi

Calcium transport, Ion transport, Transport

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-dependent L-type calcium channel subunit alpha-1FImported
Gene namesi
Name:Cacna1fImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:1859639. Cacna1f.

Subcellular locationi

Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

  1. plasma membrane Source: RefGenome
  2. voltage-gated calcium channel complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiB1AVA4.

Structurei

3D structure databases

ProteinModelPortaliB1AVA4.
SMRiB1AVA4. Positions 386-414, 1521-1601.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118827.
HOGENOMiHOG000231529.
HOVERGENiHBG050763.

Family and domain databases

Gene3Di1.20.120.350. 5 hits.
InterProiIPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR014873. VDCC_a1su_IQ.
IPR005446. VDCC_L_a1su.
IPR002077. VDCCAlpha1.
[Graphical view]
PfamiPF08763. Ca_chan_IQ. 1 hit.
PF00520. Ion_trans. 4 hits.
[Graphical view]
PRINTSiPR00167. CACHANNEL.
PR01630. LVDCCALPHA1.
SMARTiSM01062. Ca_chan_IQ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1AVA4 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSESEVGKDT TPEPSPANGT GPGPEWGLCP GPPTVGTDTS GASGLGTPRR
60 70 80 90 100
RTQHNKHKTV AVASAQRSPR ALFCLTLTNP IRRSCISIVE WKPFDILILL
110 120 130 140 150
TIFANCVALG VYIPFPEDDS NTANHNLEQV EYVFLVIFTV ETVLKIVAYG
160 170 180 190 200
LVLHPSAYIR NGWNLLDFII VVVGLFSVLL EQGPGRPGDA PHTGGKPGGF
210 220 230 240 250
DVKALRAFRV LRPLRLVSGV PSLHIVLNSI MKALVPLLHI ALLVLFVIII
260 270 280 290 300
YAIIGLELFL GRMHKTCYFL GSDMEAEEDP SPCASSGSGR SCTLNHTECR
310 320 330 340 350
GRWPGPNGGI TNFDNFFFAM LTVFQCITME GWTDVLYWMQ DAMGYELPWV
360 370 380 390 400
YFVSLVIFGS FFVLNLVLGV LSGEFSKERE KAKARGDFQK LREKQQMEED
410 420 430 440 450
LRGYLDWITQ AEELDLHDPS VDGNLASLAE EGRAGHRPQL SELTNRRRGR
460 470 480 490 500
LRWFSHSTRS THSTSSHASL PASDTGSMTD TPGDEDEEEG TMASCTRCLN
510 520 530 540 550
KIMKTRICRH FRRANRGLRA RCRRAVKSNA CYWAVLLLVF LNTLTIASEH
560 570 580 590 600
HGQPLWLTQT QEYANKVLLC LFTVEMLLKL YGLGPSVYVA SFFNRFDCFV
610 620 630 640 650
VCGGILETTL VEVGAMQPLG ISVLRCVRLL RIFKVTRHWA SLSNLVASLL
660 670 680 690 700
NSMKSIASLL LLLFLFIIIF SLLGMQLFGG KFNFDQTHTK RSTFDTFPQA
710 720 730 740 750
LLTVFQILTG EDWNVVMYDG IMAYGGPFFP GMLVCVYFII LFICGNYILL
760 770 780 790 800
NVFLAIAVDN LASGDAGTAK DKGREKSSEG NPPKENKVLV PGGENEDAKG
810 820 830 840 850
ARSEGAAPGM EEEEEEEEEE EEEEEEENGA GHVELLQEVV PKEKVVPIPE
860 870 880 890 900
GSAFFCLSQT NPLRKACHTL IHHHIFTSLI LVFIILSSVS LAAEDPIRAH
910 920 930 940 950
SFRNHILGYF DYAFTSIFTV EILLKMTVFG AFLHRGSFCR SWFNLLDLLV
960 970 980 990 1000
VSVSLISFGI HSSAISVVKI LRVLRVLRPL RAINRAKGLK HVVQCVFVAI
1010 1020 1030 1040 1050
RTIGNIMIVT TLLQFMFACI GVQLFKGKFY SCTDEAKHTL KECKGSFLIY
1060 1070 1080 1090 1100
PDGDVSRPLV RERLWVNSDF NFDNVLSAMM ALFTVSTFEG WPALLYKAID
1110 1120 1130 1140 1150
ANAEDEGPIY NYHVEISVFF IVYIIIIAFF MMNIFVGFVI ITFRAQGEQE
1160 1170 1180 1190 1200
YQNCELDKNQ RQCVEYALKA QPLRRYIPKN PHQYRVWATV NSAAFEYLMF
1210 1220 1230 1240 1250
LLILLNTVAL AMQHYEQTAP FNYAMDILNM VFTGLFTIEM VLKIIAFKPK
1260 1270 1280 1290 1300
HYFADAWNTF DALIVVGSVV DIAVTEVNSS EDSSRISITF FRLFRVMRLV
1310 1320 1330 1340 1350
KLLSKGEGIR TLLWTFIKSF QALPYVALLI AMIFFIYAVI GMQMFGKVAL
1360 1370 1380 1390 1400
QDGTQINRNN NFQTFPQAVL LLFRCATGEA WQEIMLASLP GNRCDPESDF
1410 1420 1430 1440 1450
GPGEEFTCGS SFAIVYFISF FMLCAFLIIN LFVAVIMDNF DYLTRDWSIL
1460 1470 1480 1490 1500
GPHHLDEFKR IWSEYDPGAK GRIKHLDVVA LLRRIQPPLG FGKLCPHRVA
1510 1520 1530 1540 1550
CKRLVAMNVP LNSDGTVTFN ATLFALVRTS LKIKTEGNLD QANQELRMVI
1560 1570 1580 1590 1600
KKIWKRIKQK LLDEVIPPPD EEEVTVGKFY ATFLIQDYFR KFRRRKEKGL
1610 1620 1630 1640 1650
LGREAPTSTS SALQAGLRSL QDLGPEIRQA LTYDTEEEEE EEEAVGQEAE
1660 1670 1680 1690 1700
EEEAENNPEP YKDSIDSQPQ SRWNSRISVS LPVKEKLPDS LSTGPSDDDG
1710 1720 1730 1740 1750
LAPNSRQPSV IQAGSQPHRR SSGVFMFTIP EEGSIQLKGT QGQDNQNEEQ
1760 1770 1780 1790 1800
EVPDWTPDLD EQAGTPSNPV LLPPHWSQQH VNGHHVPRRR LLPPTPAGRK
1810 1820 1830 1840 1850
PSFTIQCLQR QGSCEDLPIP GTYHRGRTSG PSRAQGSWAA PPQKGRLLYA
1860 1870 1880 1890 1900
PLLLVEESTV GEGYLGKLGG PLRTFTCLQV PGAHPNPSHR KRGSADSLVE
1910 1920 1930 1940 1950
AVLISEGLGL FAQDPRFVAL AKQEIADACH LTLDEMDSAA SDLLAQRTTS
1960 1970
LYSDEESILS RFDEEDLGDE MACVHAL
Length:1,977
Mass (Da):221,163
Last modified:April 8, 2008 - v1
Checksum:i238FCEA61C83C9E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL672231 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000115725; ENSMUSP00000111390; ENSMUSG00000031142.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL672231 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali B1AVA4.
SMRi B1AVA4. Positions 386-414, 1521-1601.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B1AVA4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000115725 ; ENSMUSP00000111390 ; ENSMUSG00000031142 .

Organism-specific databases

MGIi MGI:1859639. Cacna1f.

Phylogenomic databases

GeneTreei ENSGT00760000118827.
HOGENOMi HOG000231529.
HOVERGENi HBG050763.

Miscellaneous databases

NextBioi 35546069.
SOURCEi Search...

Family and domain databases

Gene3Di 1.20.120.350. 5 hits.
InterProi IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR014873. VDCC_a1su_IQ.
IPR005446. VDCC_L_a1su.
IPR002077. VDCCAlpha1.
[Graphical view ]
Pfami PF08763. Ca_chan_IQ. 1 hit.
PF00520. Ion_trans. 4 hits.
[Graphical view ]
PRINTSi PR00167. CACHANNEL.
PR01630. LVDCCALPHA1.
SMARTi SM01062. Ca_chan_IQ. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB1AVA4_MOUSE
AccessioniPrimary (citable) accession number: B1AVA4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3