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B1AVA4

- B1AVA4_MOUSE

UniProt

B1AVA4 - B1AVA4_MOUSE

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Protein
Submitted name: Voltage-dependent L-type calcium channel subunit alpha-1F
Gene
Cacna1f
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. high voltage-gated calcium channel activity Source: RefGenome
  2. voltage-gated calcium channel activity Source: MGI

GO - Biological processi

  1. axonogenesis Source: MGI
  2. calcium ion import Source: RefGenome
  3. cellular calcium ion homeostasis Source: MGI
  4. dendrite morphogenesis Source: MGI
  5. membrane depolarization during action potential Source: RefGenome
  6. retina development in camera-type eye Source: MGI
  7. visual perception Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Calcium channelUniRule annotation, Ion channel, Voltage-gated channelUniRule annotationSAAS annotations

Keywords - Biological processi

Calcium transport, Ion transport, Transport

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-dependent L-type calcium channel subunit alpha-1FImported
Gene namesi
Name:Cacna1fImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:1859639. Cacna1f.

Subcellular locationi

Membrane; Multi-pass membrane protein By similarity UniRule annotation

GO - Cellular componenti

  1. plasma membrane Source: RefGenome
  2. voltage-gated calcium channel complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiB1AVA4.

Structurei

3D structure databases

ProteinModelPortaliB1AVA4.
SMRiB1AVA4. Positions 386-414, 1521-1601.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00750000117620.
HOGENOMiHOG000231529.
HOVERGENiHBG050763.

Family and domain databases

Gene3Di1.20.120.350. 5 hits.
InterProiIPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR014873. VDCC_a1su_IQ.
IPR005446. VDCC_L_a1su.
IPR002077. VDCCAlpha1.
[Graphical view]
PfamiPF08763. Ca_chan_IQ. 1 hit.
PF00520. Ion_trans. 4 hits.
[Graphical view]
PRINTSiPR00167. CACHANNEL.
PR01630. LVDCCALPHA1.
SMARTiSM01062. Ca_chan_IQ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1AVA4-1 [UniParc]FASTAAdd to Basket

« Hide

MSESEVGKDT TPEPSPANGT GPGPEWGLCP GPPTVGTDTS GASGLGTPRR     50
RTQHNKHKTV AVASAQRSPR ALFCLTLTNP IRRSCISIVE WKPFDILILL 100
TIFANCVALG VYIPFPEDDS NTANHNLEQV EYVFLVIFTV ETVLKIVAYG 150
LVLHPSAYIR NGWNLLDFII VVVGLFSVLL EQGPGRPGDA PHTGGKPGGF 200
DVKALRAFRV LRPLRLVSGV PSLHIVLNSI MKALVPLLHI ALLVLFVIII 250
YAIIGLELFL GRMHKTCYFL GSDMEAEEDP SPCASSGSGR SCTLNHTECR 300
GRWPGPNGGI TNFDNFFFAM LTVFQCITME GWTDVLYWMQ DAMGYELPWV 350
YFVSLVIFGS FFVLNLVLGV LSGEFSKERE KAKARGDFQK LREKQQMEED 400
LRGYLDWITQ AEELDLHDPS VDGNLASLAE EGRAGHRPQL SELTNRRRGR 450
LRWFSHSTRS THSTSSHASL PASDTGSMTD TPGDEDEEEG TMASCTRCLN 500
KIMKTRICRH FRRANRGLRA RCRRAVKSNA CYWAVLLLVF LNTLTIASEH 550
HGQPLWLTQT QEYANKVLLC LFTVEMLLKL YGLGPSVYVA SFFNRFDCFV 600
VCGGILETTL VEVGAMQPLG ISVLRCVRLL RIFKVTRHWA SLSNLVASLL 650
NSMKSIASLL LLLFLFIIIF SLLGMQLFGG KFNFDQTHTK RSTFDTFPQA 700
LLTVFQILTG EDWNVVMYDG IMAYGGPFFP GMLVCVYFII LFICGNYILL 750
NVFLAIAVDN LASGDAGTAK DKGREKSSEG NPPKENKVLV PGGENEDAKG 800
ARSEGAAPGM EEEEEEEEEE EEEEEEENGA GHVELLQEVV PKEKVVPIPE 850
GSAFFCLSQT NPLRKACHTL IHHHIFTSLI LVFIILSSVS LAAEDPIRAH 900
SFRNHILGYF DYAFTSIFTV EILLKMTVFG AFLHRGSFCR SWFNLLDLLV 950
VSVSLISFGI HSSAISVVKI LRVLRVLRPL RAINRAKGLK HVVQCVFVAI 1000
RTIGNIMIVT TLLQFMFACI GVQLFKGKFY SCTDEAKHTL KECKGSFLIY 1050
PDGDVSRPLV RERLWVNSDF NFDNVLSAMM ALFTVSTFEG WPALLYKAID 1100
ANAEDEGPIY NYHVEISVFF IVYIIIIAFF MMNIFVGFVI ITFRAQGEQE 1150
YQNCELDKNQ RQCVEYALKA QPLRRYIPKN PHQYRVWATV NSAAFEYLMF 1200
LLILLNTVAL AMQHYEQTAP FNYAMDILNM VFTGLFTIEM VLKIIAFKPK 1250
HYFADAWNTF DALIVVGSVV DIAVTEVNSS EDSSRISITF FRLFRVMRLV 1300
KLLSKGEGIR TLLWTFIKSF QALPYVALLI AMIFFIYAVI GMQMFGKVAL 1350
QDGTQINRNN NFQTFPQAVL LLFRCATGEA WQEIMLASLP GNRCDPESDF 1400
GPGEEFTCGS SFAIVYFISF FMLCAFLIIN LFVAVIMDNF DYLTRDWSIL 1450
GPHHLDEFKR IWSEYDPGAK GRIKHLDVVA LLRRIQPPLG FGKLCPHRVA 1500
CKRLVAMNVP LNSDGTVTFN ATLFALVRTS LKIKTEGNLD QANQELRMVI 1550
KKIWKRIKQK LLDEVIPPPD EEEVTVGKFY ATFLIQDYFR KFRRRKEKGL 1600
LGREAPTSTS SALQAGLRSL QDLGPEIRQA LTYDTEEEEE EEEAVGQEAE 1650
EEEAENNPEP YKDSIDSQPQ SRWNSRISVS LPVKEKLPDS LSTGPSDDDG 1700
LAPNSRQPSV IQAGSQPHRR SSGVFMFTIP EEGSIQLKGT QGQDNQNEEQ 1750
EVPDWTPDLD EQAGTPSNPV LLPPHWSQQH VNGHHVPRRR LLPPTPAGRK 1800
PSFTIQCLQR QGSCEDLPIP GTYHRGRTSG PSRAQGSWAA PPQKGRLLYA 1850
PLLLVEESTV GEGYLGKLGG PLRTFTCLQV PGAHPNPSHR KRGSADSLVE 1900
AVLISEGLGL FAQDPRFVAL AKQEIADACH LTLDEMDSAA SDLLAQRTTS 1950
LYSDEESILS RFDEEDLGDE MACVHAL 1977
Length:1,977
Mass (Da):221,163
Last modified:April 8, 2008 - v1
Checksum:i238FCEA61C83C9E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL672231 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000115725; ENSMUSP00000111390; ENSMUSG00000031142.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL672231 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali B1AVA4.
SMRi B1AVA4. Positions 386-414, 1521-1601.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B1AVA4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000115725 ; ENSMUSP00000111390 ; ENSMUSG00000031142 .

Organism-specific databases

MGIi MGI:1859639. Cacna1f.

Phylogenomic databases

GeneTreei ENSGT00750000117620.
HOGENOMi HOG000231529.
HOVERGENi HBG050763.

Miscellaneous databases

NextBioi 35546069.
SOURCEi Search...

Family and domain databases

Gene3Di 1.20.120.350. 5 hits.
InterProi IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR014873. VDCC_a1su_IQ.
IPR005446. VDCC_L_a1su.
IPR002077. VDCCAlpha1.
[Graphical view ]
Pfami PF08763. Ca_chan_IQ. 1 hit.
PF00520. Ion_trans. 4 hits.
[Graphical view ]
PRINTSi PR00167. CACHANNEL.
PR01630. LVDCCALPHA1.
SMARTi SM01062. Ca_chan_IQ. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB1AVA4_MOUSE
AccessioniPrimary (citable) accession number: B1AVA4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: June 11, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi