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B1AVA4

- B1AVA4_MOUSE

UniProt

B1AVA4 - B1AVA4_MOUSE

Protein
Submitted name:

Voltage-dependent L-type calcium channel subunit alpha-1F

Gene

Cacna1f

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. high voltage-gated calcium channel activity Source: RefGenome
    2. voltage-gated calcium channel activity Source: MGI

    GO - Biological processi

    1. axonogenesis Source: MGI
    2. calcium ion import Source: RefGenome
    3. cellular calcium ion homeostasis Source: MGI
    4. dendrite morphogenesis Source: MGI
    5. membrane depolarization during action potential Source: RefGenome
    6. retina development in camera-type eye Source: MGI
    7. visual perception Source: MGI

    Keywords - Molecular functioni

    Calcium channelUniRule annotation, Ion channel, Voltage-gated channelUniRule annotationSAAS annotation

    Keywords - Biological processi

    Calcium transport, Ion transport, Transport

    Keywords - Ligandi

    Calcium

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Voltage-dependent L-type calcium channel subunit alpha-1FImported
    Gene namesi
    Name:Cacna1fImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome X

    Organism-specific databases

    MGIiMGI:1859639. Cacna1f.

    Subcellular locationi

    Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. plasma membrane Source: RefGenome
    2. voltage-gated calcium channel complex Source: InterPro

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Proteomic databases

    PRIDEiB1AVA4.

    Structurei

    3D structure databases

    ProteinModelPortaliB1AVA4.
    SMRiB1AVA4. Positions 386-414, 1521-1601.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. [View classification]UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117620.
    HOGENOMiHOG000231529.
    HOVERGENiHBG050763.

    Family and domain databases

    Gene3Di1.20.120.350. 5 hits.
    InterProiIPR027359. Channel_four-helix_dom.
    IPR005821. Ion_trans_dom.
    IPR014873. VDCC_a1su_IQ.
    IPR005446. VDCC_L_a1su.
    IPR002077. VDCCAlpha1.
    [Graphical view]
    PfamiPF08763. Ca_chan_IQ. 1 hit.
    PF00520. Ion_trans. 4 hits.
    [Graphical view]
    PRINTSiPR00167. CACHANNEL.
    PR01630. LVDCCALPHA1.
    SMARTiSM01062. Ca_chan_IQ. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1AVA4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSESEVGKDT TPEPSPANGT GPGPEWGLCP GPPTVGTDTS GASGLGTPRR     50
    RTQHNKHKTV AVASAQRSPR ALFCLTLTNP IRRSCISIVE WKPFDILILL 100
    TIFANCVALG VYIPFPEDDS NTANHNLEQV EYVFLVIFTV ETVLKIVAYG 150
    LVLHPSAYIR NGWNLLDFII VVVGLFSVLL EQGPGRPGDA PHTGGKPGGF 200
    DVKALRAFRV LRPLRLVSGV PSLHIVLNSI MKALVPLLHI ALLVLFVIII 250
    YAIIGLELFL GRMHKTCYFL GSDMEAEEDP SPCASSGSGR SCTLNHTECR 300
    GRWPGPNGGI TNFDNFFFAM LTVFQCITME GWTDVLYWMQ DAMGYELPWV 350
    YFVSLVIFGS FFVLNLVLGV LSGEFSKERE KAKARGDFQK LREKQQMEED 400
    LRGYLDWITQ AEELDLHDPS VDGNLASLAE EGRAGHRPQL SELTNRRRGR 450
    LRWFSHSTRS THSTSSHASL PASDTGSMTD TPGDEDEEEG TMASCTRCLN 500
    KIMKTRICRH FRRANRGLRA RCRRAVKSNA CYWAVLLLVF LNTLTIASEH 550
    HGQPLWLTQT QEYANKVLLC LFTVEMLLKL YGLGPSVYVA SFFNRFDCFV 600
    VCGGILETTL VEVGAMQPLG ISVLRCVRLL RIFKVTRHWA SLSNLVASLL 650
    NSMKSIASLL LLLFLFIIIF SLLGMQLFGG KFNFDQTHTK RSTFDTFPQA 700
    LLTVFQILTG EDWNVVMYDG IMAYGGPFFP GMLVCVYFII LFICGNYILL 750
    NVFLAIAVDN LASGDAGTAK DKGREKSSEG NPPKENKVLV PGGENEDAKG 800
    ARSEGAAPGM EEEEEEEEEE EEEEEEENGA GHVELLQEVV PKEKVVPIPE 850
    GSAFFCLSQT NPLRKACHTL IHHHIFTSLI LVFIILSSVS LAAEDPIRAH 900
    SFRNHILGYF DYAFTSIFTV EILLKMTVFG AFLHRGSFCR SWFNLLDLLV 950
    VSVSLISFGI HSSAISVVKI LRVLRVLRPL RAINRAKGLK HVVQCVFVAI 1000
    RTIGNIMIVT TLLQFMFACI GVQLFKGKFY SCTDEAKHTL KECKGSFLIY 1050
    PDGDVSRPLV RERLWVNSDF NFDNVLSAMM ALFTVSTFEG WPALLYKAID 1100
    ANAEDEGPIY NYHVEISVFF IVYIIIIAFF MMNIFVGFVI ITFRAQGEQE 1150
    YQNCELDKNQ RQCVEYALKA QPLRRYIPKN PHQYRVWATV NSAAFEYLMF 1200
    LLILLNTVAL AMQHYEQTAP FNYAMDILNM VFTGLFTIEM VLKIIAFKPK 1250
    HYFADAWNTF DALIVVGSVV DIAVTEVNSS EDSSRISITF FRLFRVMRLV 1300
    KLLSKGEGIR TLLWTFIKSF QALPYVALLI AMIFFIYAVI GMQMFGKVAL 1350
    QDGTQINRNN NFQTFPQAVL LLFRCATGEA WQEIMLASLP GNRCDPESDF 1400
    GPGEEFTCGS SFAIVYFISF FMLCAFLIIN LFVAVIMDNF DYLTRDWSIL 1450
    GPHHLDEFKR IWSEYDPGAK GRIKHLDVVA LLRRIQPPLG FGKLCPHRVA 1500
    CKRLVAMNVP LNSDGTVTFN ATLFALVRTS LKIKTEGNLD QANQELRMVI 1550
    KKIWKRIKQK LLDEVIPPPD EEEVTVGKFY ATFLIQDYFR KFRRRKEKGL 1600
    LGREAPTSTS SALQAGLRSL QDLGPEIRQA LTYDTEEEEE EEEAVGQEAE 1650
    EEEAENNPEP YKDSIDSQPQ SRWNSRISVS LPVKEKLPDS LSTGPSDDDG 1700
    LAPNSRQPSV IQAGSQPHRR SSGVFMFTIP EEGSIQLKGT QGQDNQNEEQ 1750
    EVPDWTPDLD EQAGTPSNPV LLPPHWSQQH VNGHHVPRRR LLPPTPAGRK 1800
    PSFTIQCLQR QGSCEDLPIP GTYHRGRTSG PSRAQGSWAA PPQKGRLLYA 1850
    PLLLVEESTV GEGYLGKLGG PLRTFTCLQV PGAHPNPSHR KRGSADSLVE 1900
    AVLISEGLGL FAQDPRFVAL AKQEIADACH LTLDEMDSAA SDLLAQRTTS 1950
    LYSDEESILS RFDEEDLGDE MACVHAL 1977
    Length:1,977
    Mass (Da):221,163
    Last modified:April 8, 2008 - v1
    Checksum:i238FCEA61C83C9E9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL672231 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000115725; ENSMUSP00000111390; ENSMUSG00000031142.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL672231 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali B1AVA4.
    SMRi B1AVA4. Positions 386-414, 1521-1601.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi B1AVA4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000115725 ; ENSMUSP00000111390 ; ENSMUSG00000031142 .

    Organism-specific databases

    MGIi MGI:1859639. Cacna1f.

    Phylogenomic databases

    GeneTreei ENSGT00750000117620.
    HOGENOMi HOG000231529.
    HOVERGENi HBG050763.

    Miscellaneous databases

    NextBioi 35546069.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 1.20.120.350. 5 hits.
    InterProi IPR027359. Channel_four-helix_dom.
    IPR005821. Ion_trans_dom.
    IPR014873. VDCC_a1su_IQ.
    IPR005446. VDCC_L_a1su.
    IPR002077. VDCCAlpha1.
    [Graphical view ]
    Pfami PF08763. Ca_chan_IQ. 1 hit.
    PF00520. Ion_trans. 4 hits.
    [Graphical view ]
    PRINTSi PR00167. CACHANNEL.
    PR01630. LVDCCALPHA1.
    SMARTi SM01062. Ca_chan_IQ. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiB1AVA4_MOUSE
    AccessioniPrimary (citable) accession number: B1AVA4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3