NHS actin-remodeling regulator

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• cell differentiation Source: MGI <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • 8282045
• lens development in camera-type eye Source: MGI <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • 8282045

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MPFAKRIVEP QWLCRQRRPA PGPDEDTSGG SVEPPPPLQP PGRREEAEAP 
        60         70         80         90        100
EPEEPPRVPP APLPLPPLPP SLPAPAEQDQ QPPSEAREAG EESVAGVSEA 
       110        120        130        140        150
ASAPGETSEA SAEAVLLMLD LCAVSNAALA RVLRQLSDVA RHACSLFQEL 
       160        170        180        190        200
ESDIQLTHRR VWALQGKLGS VQRVLSTLDP KQEAVPVSNL DIESKLSVYY 
       210        220        230        240        250
RAPWHQQRNI FLPATRPPCV EELHRHARQS LQALRREHRS RSDRREQRAA 
       260        270        280        290        300
APLPIAAPPL PAYPPAHSQR RREAKDRHFL TFNSTRSPSP TECCHMAPWS 
       310        320        330        340        350
RKSHSPEDED TDAMLGQRPK NPIHNVPSTL DKQTNWNKAL PLPTPEEKMK 
       360        370        380        390        400
QDAQVISSCI IPINVTGVGF DREASIRCSL VHSQSVLQRR RKLRRRKTIS 
       410        420        430        440        450
GIPRRVQQEI DSDESPVARE RNVIVHTNPD PSNTVNRRSG TRDSECQTED 
       460        470        480        490        500
ILIAAPSRRR IRAQRGQSIA ASLSHSAGNI SALADKGDTM FTPVVSSRTR 
       510        520        530        540        550
SRSLPREGNR GGDAEPKVGA KPSAFEEGER FVGDHERTPN DCSEAPSSPS 
       560        570        580        590        600
TQEHQPALGL ACSQHLHSPQ QKLSERGRSR LSRMAADSGS CDISSNSDTF 
       610        620        630        640        650
GSPVHCISTA SVLLSSHMDQ KEDHQSSSGN WSGSSSTCPS QTSETIPPAA 
       660        670        680        690        700
SPPLTGSSHC DSELSLNTAP NANEDASVFV TEQYNDHLDK VRGHRTNSFT 
       710        720        730        740        750
STVADLLDDP NNSNTSDSEW NYLHHHHDAS CRQDFSPERP KADSLGCPSF 
       760        770        780        790        800
TSMGTYDSFL EKSPSDKADT SSHFSVDTEG YYTSMHFDCG LKGNKTYVCH 
       810        820        830        840        850
YAGLGPENGQ GVGVPPALPD CAWQEYLDHR RQGRPSISFR KPKAKPTPPK 
       860        870        880        890        900
RSSSLRKSDG NADISEKKEP KISSGQHLPH SSREMKLPLD FSNTPSRVEN 
       910        920        930        940        950
ANLPAKLDSS WINQSEHAIK EPQLDTPDIS PFKDEGAEST HYADLWLLND 
       960        970        980        990       1000
LKTNDPYRSL SNSSTATGTT VIECIKSPES SESQTSQSES RATTPSLPSV 
      1010       1020       1030       1040       1050
DNEYKLASPE KLAGLASPSS GYSSQSETPT SSFPTAFFSG PLSPGGSKRK 
      1060       1070       1080       1090       1100
PKVPERKSSL QQPSLKDGAL SLSKDFELPI IPPSHLDLSA LHVLNKPFHH 
      1110       1120       1130       1140       1150
RHPLHVFTHK QNTVGDMPRS NPAPSLAITP TVLKSVNLRS ISKSEEVRQK 
      1160       1170       1180       1190       1200
EGNNTDLPYL EENAATAASV ASLSPSKARP HTAKKSISRQ YSAEDTLLPF 
      1210       1220       1230       1240       1250
LDSSVAEMGP EKHLEKNPNF DGKSHGDPET ATSASSNLPD SNVMKEQIQM 
      1260       1270       1280       1290       1300
ESELISENIL SKNCGFSTGF QRVSASRPSD LGSKMIQYGA SPDGTVQQGQ 
      1310       1320       1330       1340       1350
KAPSGVREEG GKPESVDGIT LQANSSTRVT DISSQYKHQR VISRHHDKVP 
      1360       1370       1380       1390       1400
VTIRHESEMS TVNSFPEKCS EQENIASGIS PQSASDNSRA EETQGSMDET 
      1410       1420       1430       1440       1450
SLKESSPSDD SITSPLSEDS QAGAEGVFVS PNKPRTTEDL FAVIHRSKRK 
      1460       1470       1480       1490       1500
VLGRKDSGDM SVRSKSRVPL GSSSSSANSV TSPSSNVTAG TSQRSPGLIY 
      1510       1520       1530       1540       1550
RNAKKSNTSN EEFKLLLLKK GSRSDSSYRM SATEILKSPV LPKPPGEFTA 
      1560       1570       1580       1590       1600
ESPQSPDDTH QGTPGTEALS PLSPCSPRVN AEGFSSKNFA TSASARVGRS 
      1610       1620       1630       1640 
RVPPVASSSR YSVRCRLYNT PMQAISEGET ENSDGSPHDD RSSQSST    

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ