B1AUQ5 (B1AUQ5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Gamma-aminobutyric acid receptor subunit theta Ensembl ENSMUSP00000110200

Gene names

Name:

Gabrq Ensembl ENSMUSP00000110200 MGI 1888498

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000110200

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	525 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification] RuleBase RU000687
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000110200

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Cell junction Cell membrane SAAS SAAS006028 Membrane Postsynaptic cell membrane SAAS SAAS006202 Synapse
Domain	Transmembrane Transmembrane helix SAAS SAAS006202
Molecular function	Ion channel RuleBase RU000687 SAAS SAAS006028
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	chloride transport Inferred from sequence or structural similarity PubMed 10804200. Source: MGI gamma-aminobutyric acid signaling pathway Inferred from sequence or structural similarity PubMed 10804200. Source: MGI
Cellular_component	cell junction Inferred from electronic annotation. Source: UniProtKB-KW integral to plasma membrane Inferred from sequence or structural similarity PubMed 10804200. Source: MGI postsynaptic membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	GABA-A receptor activity Inferred from sequence or structural similarity PubMed 10804200. Source: MGI extracellular ligand-gated ion channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1AUQ5 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: C916E3A54BC50263	FASTA	525	59,671
	10 20 30 40 50 60 MGIRGMLRAA ALLLLIRTWL AESNGPSPTP KFHFELSSST PEVILDLFNC KNCANEAVVQ 70 80 90 100 110 120 KILDRVLSTY DVRLRPNFGG APVPVSVSIY VSSIEQISEI NMDYTITMFL HQTWKDTRLA 130 140 150 160 170 180 YYETNLNLTL DYRMHEKLWV PDCYFVNSKD AFVHDVTVEN RVFQLHPDGT VRYGIRLTTT 190 200 210 220 230 240 AACSLDLQKF PMDKQSCKLE VESYGYTVED IVLSWEDDNA IHITDGLHIP QYTYLGRTIT 250 260 270 280 290 300 SKEVYFYTGS YMRLIVKFQV QREVRSYLVQ VYWPTVLTTI LSWISFWMNY DSSAARVTIG 310 320 330 340 350 360 LTSILVLTTI DSHMRDKLPH ISCIKAIDIY ILVCLFFVFL SLLEYVYINY LFFSQVPRRN 370 380 390 400 410 420 HRRCRKPRRV VARYRYQEVV VANVQDGLIN VEDRVEDRAG PLPDSPMQAH LASQESLGSL 430 440 450 460 470 480 VFTSEQAQLA TSESLSLLSS ASSQTQLATG ESLSDLPSTS EQTVPECTIH FHGFLTNDSI 490 500 510 520 IPIKIHSRSD ACDDEDSEES LSSEESHGHG SSHTGRLKLQ ISQSA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000110200.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000110200.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL671908 Genomic DNA. No translation available.
IPI	IPI00776309.
3D structure databases
ProteinModelPortal	B1AUQ5.
SMR	B1AUQ5. Positions 61-351.
ModBase	Search...
Proteomic databases
PRIDE	B1AUQ5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000114553; ENSMUSP00000110200; ENSMUSG00000031344.
UCSC	uc009tkr.1. mouse.
Organism-specific databases
MGI	MGI:1888498. Gabrq.
Phylogenomic databases
GeneTree	ENSGT00630000089685.
HOGENOM	HOG000049189.
HOVERGEN	HBG051708.
Gene expression databases
ArrayExpress	B1AUQ5.
Family and domain databases
Gene3D	2.70.170.10. 1 hit.
InterPro	IPR006028. GABAA_rcpt. IPR008101. GABAAt_rcpt. IPR006202. Neur_chan_lig-bd. IPR006201. Neur_channel. IPR006029. Neurotrans-gated_channel_TM. IPR018000. Neurotransmitter_ion_chnl_CS. [Graphical view]
PANTHER	PTHR18945. PTHR18945. 1 hit. PTHR18945:SF87. PTHR18945:SF87. 1 hit.
Pfam	PF02931. Neur_chan_LBD. 1 hit. PF02932. Neur_chan_memb. 1 hit. [Graphical view]
PRINTS	PR00253. GABAARECEPTR. PR01725. GABAARTHETA. PR00252. NRIONCHANNEL.
SUPFAM	SSF90112. Neu_channel_TM. 1 hit. SSF63712. Neur_chan_LBD. 1 hit.
TIGRFAMs	TIGR00860. LIC. 1 hit.
PROSITE	PS00236. NEUROTR_ION_CHANNEL. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35546019.
SOURCE	Search...

Entry information

Entry name

B1AUQ5_MOUSE

Accession

Primary (citable) accession number: B1AUQ5

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	May 29, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)