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Protein

Peroxisome biogenesis factor 10

Gene

Pex10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Somewhat implicated in the biogenesis of peroxisomes.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri271 – 30939RING-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Peroxisome biogenesis

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisome biogenesis factor 10
Alternative name(s):
Peroxin-10
Peroxisomal biogenesis factor 10
Peroxisome assembly protein 10
Gene namesi
Name:Pex10
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2684988. Pex10.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 324324Peroxisome biogenesis factor 10PRO_0000346862Add
BLAST

Proteomic databases

EPDiB1AUE5.
MaxQBiB1AUE5.
PaxDbiB1AUE5.
PeptideAtlasiB1AUE5.
PRIDEiB1AUE5.

PTM databases

iPTMnetiB1AUE5.

Expressioni

Gene expression databases

BgeeiB1AUE5.
GenevisibleiB1AUE5. MM.

Interactioni

Subunit structurei

Interacts with PEX19.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099469.

Structurei

3D structure databases

ProteinModelPortaliB1AUE5.
SMRiB1AUE5. Positions 238-319.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pex2/pex10/pex12 family.Curated
Contains 1 RING-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri271 – 30939RING-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG0317. Eukaryota.
COG5574. LUCA.
GeneTreeiENSGT00510000048446.
HOGENOMiHOG000180194.
HOVERGENiHBG053568.
InParanoidiB1AUE5.
KOiK13346.
OMAiIYLRHYR.
OrthoDBiEOG7C8GHZ.
PhylomeDBiB1AUE5.
TreeFamiTF326491.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR025654. PEX10.
IPR006845. Pex_N.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PANTHERiPTHR23350. PTHR23350. 1 hit.
PfamiPF04757. Pex2_Pex12. 1 hit.
[Graphical view]
SMARTiSM00184. RING. 1 hit.
[Graphical view]
PROSITEiPS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1AUE5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARAGAPEVI RAAQKDEYYL GGLRSAAGEA LHSLAGAKKW LEWRKEIELL
60 70 80 90 100
SDIAYFGLTT IAGYQTLGEE YVGIIQVDPS QQRVPSRLRR AALVALHAVL
110 120 130 140 150
PYLLDKALLP LEQELQADGD APRASQGSLL PGGRSRSGAR RWVRHHAATL
160 170 180 190 200
TEQQRKALQR AVFILRQGFA CLHRLHVAWF YIHGTFYHLA KRLAGITYLR
210 220 230 240 250
TRRLPGEDQK ARTSYGLLGL ISLLHLVLSM GLRLYSFRQK QRARKEWRLH
260 270 280 290 300
RNLSHRRSSL EDRAVCRTPL CTLCLEERRH STATPCGHLF CWECITEWCN
310 320
TKTECPLCRE KFPPQKLVYL RHYR
Length:324
Mass (Da):37,157
Last modified:April 8, 2008 - v1
Checksum:i421ADFECDB413B35
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL670413 Genomic DNA. Translation: CAM20044.1.
CH466594 Genomic DNA. Translation: EDL14991.1.
BC147304 mRNA. Translation: AAI47305.1.
BC147305 mRNA. Translation: AAI47306.1.
CCDSiCCDS19021.1.
RefSeqiNP_001035866.1. NM_001042407.1.
UniGeneiMm.133114.

Genome annotation databases

EnsembliENSMUST00000103180; ENSMUSP00000099469; ENSMUSG00000029047.
GeneIDi668173.
KEGGimmu:668173.
UCSCiuc008wcs.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL670413 Genomic DNA. Translation: CAM20044.1.
CH466594 Genomic DNA. Translation: EDL14991.1.
BC147304 mRNA. Translation: AAI47305.1.
BC147305 mRNA. Translation: AAI47306.1.
CCDSiCCDS19021.1.
RefSeqiNP_001035866.1. NM_001042407.1.
UniGeneiMm.133114.

3D structure databases

ProteinModelPortaliB1AUE5.
SMRiB1AUE5. Positions 238-319.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099469.

PTM databases

iPTMnetiB1AUE5.

Proteomic databases

EPDiB1AUE5.
MaxQBiB1AUE5.
PaxDbiB1AUE5.
PeptideAtlasiB1AUE5.
PRIDEiB1AUE5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000103180; ENSMUSP00000099469; ENSMUSG00000029047.
GeneIDi668173.
KEGGimmu:668173.
UCSCiuc008wcs.1. mouse.

Organism-specific databases

CTDi5192.
MGIiMGI:2684988. Pex10.

Phylogenomic databases

eggNOGiKOG0317. Eukaryota.
COG5574. LUCA.
GeneTreeiENSGT00510000048446.
HOGENOMiHOG000180194.
HOVERGENiHBG053568.
InParanoidiB1AUE5.
KOiK13346.
OMAiIYLRHYR.
OrthoDBiEOG7C8GHZ.
PhylomeDBiB1AUE5.
TreeFamiTF326491.

Miscellaneous databases

PROiB1AUE5.
SOURCEiSearch...

Gene expression databases

BgeeiB1AUE5.
GenevisibleiB1AUE5. MM.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR025654. PEX10.
IPR006845. Pex_N.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PANTHERiPTHR23350. PTHR23350. 1 hit.
PfamiPF04757. Pex2_Pex12. 1 hit.
[Graphical view]
SMARTiSM00184. RING. 1 hit.
[Graphical view]
PROSITEiPS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiPEX10_MOUSE
AccessioniPrimary (citable) accession number: B1AUE5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: April 8, 2008
Last modified: July 6, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.