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Protein

Peroxisome biogenesis factor 10

Gene

Pex10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Somewhat implicated in the biogenesis of peroxisomes.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri271 – 309RING-typePROSITE-ProRule annotationAdd BLAST39

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processPeroxisome biogenesis
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-8866654 E3 ubiquitin ligases ubiquitinate target proteins
R-MMU-9033241 Peroxisomal protein import

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisome biogenesis factor 10
Alternative name(s):
Peroxin-10
Peroxisomal biogenesis factor 10
Peroxisome assembly protein 10
Gene namesi
Name:Pex10
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2684988 Pex10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003468621 – 324Peroxisome biogenesis factor 10Add BLAST324

Proteomic databases

MaxQBiB1AUE5
PaxDbiB1AUE5
PeptideAtlasiB1AUE5
PRIDEiB1AUE5

PTM databases

iPTMnetiB1AUE5
PhosphoSitePlusiB1AUE5

Expressioni

Gene expression databases

BgeeiENSMUSG00000029047
GenevisibleiB1AUE5 MM

Interactioni

Subunit structurei

Interacts with PEX19.By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi579973, 1 interactor
STRINGi10090.ENSMUSP00000099469

Structurei

3D structure databases

ProteinModelPortaliB1AUE5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pex2/pex10/pex12 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri271 – 309RING-typePROSITE-ProRule annotationAdd BLAST39

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG0317 Eukaryota
COG5574 LUCA
GeneTreeiENSGT00510000048446
HOGENOMiHOG000180194
HOVERGENiHBG053568
InParanoidiB1AUE5
KOiK13346
OMAiSYHGFAS
OrthoDBiEOG091G0IDS
PhylomeDBiB1AUE5
TreeFamiTF326491

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR025654 PEX10
IPR006845 Pex_N
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PANTHERiPTHR23350 PTHR23350, 1 hit
PfamiView protein in Pfam
PF04757 Pex2_Pex12, 1 hit
SMARTiView protein in SMART
SM00184 RING, 1 hit
PROSITEiView protein in PROSITE
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

B1AUE5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARAGAPEVI RAAQKDEYYL GGLRSAAGEA LHSLAGAKKW LEWRKEIELL
60 70 80 90 100
SDIAYFGLTT IAGYQTLGEE YVGIIQVDPS QQRVPSRLRR AALVALHAVL
110 120 130 140 150
PYLLDKALLP LEQELQADGD APRASQGSLL PGGRSRSGAR RWVRHHAATL
160 170 180 190 200
TEQQRKALQR AVFILRQGFA CLHRLHVAWF YIHGTFYHLA KRLAGITYLR
210 220 230 240 250
TRRLPGEDQK ARTSYGLLGL ISLLHLVLSM GLRLYSFRQK QRARKEWRLH
260 270 280 290 300
RNLSHRRSSL EDRAVCRTPL CTLCLEERRH STATPCGHLF CWECITEWCN
310 320
TKTECPLCRE KFPPQKLVYL RHYR
Length:324
Mass (Da):37,157
Last modified:April 8, 2008 - v1
Checksum:i421ADFECDB413B35
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL670413 Genomic DNA Translation: CAM20044.1
CH466594 Genomic DNA Translation: EDL14991.1
BC147304 mRNA Translation: AAI47305.1
BC147305 mRNA Translation: AAI47306.1
CCDSiCCDS19021.1
RefSeqiNP_001035866.1, NM_001042407.1
UniGeneiMm.133114

Genome annotation databases

EnsembliENSMUST00000103180; ENSMUSP00000099469; ENSMUSG00000029047
GeneIDi668173
KEGGimmu:668173
UCSCiuc008wcs.1 mouse

Similar proteinsi

Entry informationi

Entry nameiPEX10_MOUSE
AccessioniPrimary (citable) accession number: B1AUE5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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