B1AU25 (B1AU25_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Apoptosis-inducing factor 1, mitochondrial Ensembl ENSMUSP00000110595

Gene names

Name:

Aifm1 Ensembl ENSMUSP00000110595 MGI 1349419

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000110595

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	608 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000110595

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	apoptotic DNA fragmentation Inferred from genetic interaction PubMed 15703386. Source: MGI apoptotic mitochondrial changes Traceable author statement PubMed 10913597. Source: MGI cell redox homeostasis Inferred from electronic annotation. Source: InterPro neuron apoptotic process Inferred from genetic interaction PubMed 15703386. Source: MGI
Cellular_component	cytosol Inferred from direct assay PubMed 19139267. Source: MGI mitochondrial intermembrane space Traceable author statement PubMed 10913597. Source: MGI mitochondrial outer membrane Traceable author statement PubMed 14561754. Source: MGI nucleus Inferred from direct assay PubMed 14707049PubMed 16469926. Source: MGI
Molecular_function	electron-transferring-flavoprotein dehydrogenase activity Traceable author statement PubMed 10913597. Source: MGI flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1AU25 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 920D716B597A0E6F	FASTA	608	66,114
	10 20 30 40 50 60 MFRCGGLAGA FKQKLVPLVR TVYVQRPKQR NRLPVVQCHL LGSPSRTLAS AGASGKDGSS 70 80 90 100 110 120 LVYFLIVGAT VTGAGIYYAY KTIKEDQKRY NERVMGLGLS PEEKQRRAIA SATEGGSVPQ 130 140 150 160 170 180 IRAPSHVPFL LIGGGTAAFA AARSIRARDP GARVLIVSED PELPYMRPPL SKELWFSDDP 190 200 210 220 230 240 NVTKTLQFRQ WNGKERSIYF QPPSFYVSAQ DLPNIENGGV AVLTGKKVVH LDVRGNMVKL 250 260 270 280 290 300 NDGSQITFEK CLIATGGTPR SLSAIDRAGA EVKSRTTLFR KIGDFRALEK ISREVKSITV 310 320 330 340 350 360 IGGGFLGSEL ACALGRKSQA SGIEVIQLFP EKGNMGKILP QYLSNWTMEK VKREGVKVMP 370 380 390 400 410 420 NAIVQSVGVS GGRLLIKLKD GRKVETDHIV TAVGLEPNVE LAKTGGLEID SDFGGFRVNA 430 440 450 460 470 480 ELQARSNIWV AGDAACFYDI KLGRRRVEHH DHAVVSGRLA GENMTGAAKP YWHQSMFWSD 490 500 510 520 530 540 LGPDVGYEAI GLVDSSLPTV GVFAKATAQD NPKSATEQSG TGIRSESETE SEASEITIPP 550 560 570 580 590 600 SAPAVPQVPV EGEDYGKGVI FYLRDKVVVG IVLWNVFNRM PIARKIIKDG EQHEDLNEVA KLFNIHED

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000110595.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000110595.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL669901 Genomic DNA. No translation available.
IPI	IPI00776047.
3D structure databases
ProteinModelPortal	B1AU25.
SMR	B1AU25. Positions 117-606.
ModBase	Search...
Proteomic databases
PRIDE	B1AU25.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000114945; ENSMUSP00000110595; ENSMUSG00000036932.
Organism-specific databases
MGI	MGI:1349419. Aifm1.
Phylogenomic databases
GeneTree	ENSGT00530000063416.
HOGENOM	HOG000264253.
HOVERGEN	HBG053538.
Gene expression databases
ArrayExpress	B1AU25.
Family and domain databases
Gene3D	3.30.390.30. 1 hit.
InterPro	IPR016156. FAD/NAD-linked_Rdtase_dimer. IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR004099. Pyr_nucl-diS_OxRdtase_dimer. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. [Graphical view]
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR.
SUPFAM	SSF55424. FAD/NAD-linked_reductase_dimer. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	AIFM1. mouse.
NextBio	35545958.
SOURCE	Search...

Entry information

Entry name

B1AU25_MOUSE

Accession

Primary (citable) accession number: B1AU25

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	May 29, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)