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Protein
Submitted name:

Apoptosis-inducing factor 1, mitochondrial

Gene

Aifm1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Apoptosis-inducing factor 1, mitochondrialImported
Gene namesi
Name:Aifm1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1349419. Aifm1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei61 – 8020HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

MaxQBiB1AU25.
PeptideAtlasiB1AU25.
PRIDEiB1AU25.

Expressioni

Gene expression databases

BgeeiENSMUSG00000036932.
ExpressionAtlasiB1AU25. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB1AU25.
SMRiB1AU25. Positions 117-606.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini46 – 9752AIF-MLSInterPro annotationAdd
BLAST
Domaini131 – 455325FAD/NAD-binding_domInterPro annotationAdd
BLAST
Domaini460 – 589130AIF_CInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00530000063416.
HOGENOMiHOG000264253.
HOVERGENiHBG053538.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 3 hits.
InterProiIPR029324. AIF_C.
IPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR032773. MGARP_N.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
[Graphical view]
PfamiPF14962. AIF-MLS. 1 hit.
PF14721. AIF_C. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
SSF55424. SSF55424. 1 hit.

Sequencei

Sequence statusi: Complete.

B1AU25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRCGGLAGA FKQKLVPLVR TVYVQRPKQR NRLPVVQCHL LGSPSRTLAS
60 70 80 90 100
AGASGKDGSS LVYFLIVGAT VTGAGIYYAY KTIKEDQKRY NERVMGLGLS
110 120 130 140 150
PEEKQRRAIA SATEGGSVPQ IRAPSHVPFL LIGGGTAAFA AARSIRARDP
160 170 180 190 200
GARVLIVSED PELPYMRPPL SKELWFSDDP NVTKTLQFRQ WNGKERSIYF
210 220 230 240 250
QPPSFYVSAQ DLPNIENGGV AVLTGKKVVH LDVRGNMVKL NDGSQITFEK
260 270 280 290 300
CLIATGGTPR SLSAIDRAGA EVKSRTTLFR KIGDFRALEK ISREVKSITV
310 320 330 340 350
IGGGFLGSEL ACALGRKSQA SGIEVIQLFP EKGNMGKILP QYLSNWTMEK
360 370 380 390 400
VKREGVKVMP NAIVQSVGVS GGRLLIKLKD GRKVETDHIV TAVGLEPNVE
410 420 430 440 450
LAKTGGLEID SDFGGFRVNA ELQARSNIWV AGDAACFYDI KLGRRRVEHH
460 470 480 490 500
DHAVVSGRLA GENMTGAAKP YWHQSMFWSD LGPDVGYEAI GLVDSSLPTV
510 520 530 540 550
GVFAKATAQD NPKSATEQSG TGIRSESETE SEASEITIPP SAPAVPQVPV
560 570 580 590 600
EGEDYGKGVI FYLRDKVVVG IVLWNVFNRM PIARKIIKDG EQHEDLNEVA

KLFNIHED
Length:608
Mass (Da):66,114
Last modified:April 8, 2008 - v1
Checksum:i920D716B597A0E6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL669901 Genomic DNA. No translation available.
RefSeqiNP_001277293.1. NM_001290364.1.
UniGeneiMm.240434.

Genome annotation databases

EnsembliENSMUST00000114945; ENSMUSP00000110595; ENSMUSG00000036932.
GeneIDi26926.
UCSCiuc057arf.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL669901 Genomic DNA. No translation available.
RefSeqiNP_001277293.1. NM_001290364.1.
UniGeneiMm.240434.

3D structure databases

ProteinModelPortaliB1AU25.
SMRiB1AU25. Positions 117-606.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB1AU25.
PeptideAtlasiB1AU25.
PRIDEiB1AU25.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000114945; ENSMUSP00000110595; ENSMUSG00000036932.
GeneIDi26926.
UCSCiuc057arf.1. mouse.

Organism-specific databases

CTDi9131.
MGIiMGI:1349419. Aifm1.

Phylogenomic databases

GeneTreeiENSGT00530000063416.
HOGENOMiHOG000264253.
HOVERGENiHBG053538.

Miscellaneous databases

ChiTaRSiAifm1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000036932.
ExpressionAtlasiB1AU25. baseline and differential.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 3 hits.
InterProiIPR029324. AIF_C.
IPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR032773. MGARP_N.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
[Graphical view]
PfamiPF14962. AIF-MLS. 1 hit.
PF14721. AIF_C. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
SSF55424. SSF55424. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB1AU25_MOUSE
AccessioniPrimary (citable) accession number: B1AU25
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 7, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.