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Protein
Submitted name:

N-sulfoglucosamine sulfohydrolase (sulfamidase)

Gene

Sgsh

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-2024096 HS-GAG degradation

Names & Taxonomyi

Protein namesi
Submitted name:
N-sulfoglucosamine sulfohydrolase (sulfamidase)Imported
Gene namesi
Name:SgshImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1350341 Sgsh

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500276193223 – 422Sequence analysisAdd BLAST400

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei703-oxoalanine (Cys)UniRule annotation1

Post-translational modificationi

The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.UniRule annotation

Proteomic databases

MaxQBiB1ATE0
PeptideAtlasiB1ATE0
PRIDEiB1ATE0

Expressioni

Gene expression databases

BgeeiENSMUSG00000005043
ExpressionAtlasiB1ATE0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB1ATE0
SMRiB1ATE0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 248SulfataseInterPro annotationAdd BLAST226

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3867 Eukaryota
COG3119 LUCA
GeneTreeiENSGT00390000013080
HOGENOMiHOG000207959
HOVERGENiHBG064229

Family and domain databases

Gene3Di3.40.720.10, 1 hit
InterProiView protein in InterPro
IPR017849 Alkaline_Pase-like_a/b/a
IPR017850 Alkaline_phosphatase_core_sf
IPR024607 Sulfatase_CS
IPR000917 Sulfatase_N
PfamiView protein in Pfam
PF00884 Sulfatase, 1 hit
SUPFAMiSSF53649 SSF53649, 2 hits
PROSITEiView protein in PROSITE
PS00523 SULFATASE_1, 1 hit
PS00149 SULFATASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

B1ATE0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHCPGLACCT ILLVLGLCGA HSRNVLLIVA DDGGFESGVY NNTAIATPHL
60 70 80 90 100
DALSRHSLIF RNAFTSVSSC SPSRASLLTG LPQHQNGMYG LHQDVHHFNS
110 120 130 140 150
FDKVQSLPLL LNQAGVRTGI IGKKHVGPET VYPFDFAFTE ENSSVMQVGR
160 170 180 190 200
NITRIKQLVQ KFLQTQDDRP FFLYVAFHDP HRCGHSQPQY GTFCEKFGNG
210 220 230 240 250
ESGMGYIPDW TPQIYDPQDV MVPYFVPDTP AARADLAAQY TTIGRMDQER
260 270 280 290 300
QDQPVLARYS RAFAGVISRA PTALGPGQRR LREPSRPHPY HPGLVLHPVP
310 320 330 340 350
QLCHLWLKDD PAHRPIPPAG AGGRAPLGHC LQQPEPPRGH HVLPDALGVP
360 370 380 390 400
PELPPHSQPE LQDAISHRPR FLCLADLPGP PEPNHHRPAH GLVQGPPPLL
410 420
LPGTLGTLRH QPGPSRDTEP GR
Length:422
Mass (Da):46,311
Last modified:April 8, 2008 - v1
Checksum:iE01F5706346C16B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645911 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000100172; ENSMUSP00000097748; ENSMUSG00000005043

Similar proteinsi

Entry informationi

Entry nameiB1ATE0_MOUSE
AccessioniPrimary (citable) accession number: B1ATE0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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