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Protein
Submitted name:

MCG9626, isoform CRA_b

Gene

Mtmr3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1080 – 1140FYVE-typePROSITE-ProRule annotationAdd BLAST61

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-1632852. Macroautophagy.
R-MMU-1660499. Synthesis of PIPs at the plasma membrane.

Names & Taxonomyi

Protein namesi
Submitted name:
MCG9626, isoform CRA_bImported
Submitted name:
Myotubularin-related protein 3Imported
Gene namesi
Name:Mtmr3Imported
ORF Names:mCG_9626Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1921552. Mtmr3.

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSMUSG00000034354.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 576Myotubularin phosphataseInterPro annotationAdd BLAST422
Domaini1080 – 1140FYVE-typeInterPro annotationAdd BLAST61

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1033 – 1060Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.SAAS annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1080 – 1140FYVE-typePROSITE-ProRule annotationAdd BLAST61

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4471. Eukaryota.
ENOG410XPTU. LUCA.
GeneTreeiENSGT00760000118832.
HOGENOMiHOG000004861.
HOVERGENiHBG052526.
KOiK18082.

Family and domain databases

CDDicd13341. PH-GRAM_MTMR3. 1 hit.
Gene3Di2.30.29.30. 1 hit.
3.30.40.10. 1 hit.
3.90.190.10. 1 hit.
InterProiView protein in InterPro
IPR035888. MTMR3_PH-GRAM.
IPR010569. Myotubularin-like_Pase_dom.
IPR030564. Myotubularin_fam.
IPR011993. PH-like_dom_sf.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000306. Znf_FYVE.
IPR017455. Znf_FYVE-rel.
IPR011011. Znf_FYVE_PHD.
IPR013083. Znf_RING/FYVE/PHD.
PANTHERiPTHR10807. PTHR10807. 2 hits.
PfamiView protein in Pfam
PF01363. FYVE. 1 hit.
PF06602. Myotub-related. 1 hit.
SMARTiView protein in SMART
SM00064. FYVE. 1 hit.
SM00404. PTPc_motif. 1 hit.
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF52799. SSF52799. 2 hits.
SSF57903. SSF57903. 1 hit.
PROSITEiView protein in PROSITE
PS51339. PPASE_MYOTUBULARIN. 1 hit.
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50178. ZF_FYVE. 1 hit.

Sequencei

Sequence statusi: Complete.

B1ATD5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEEMRHSLE CIQANQIFPR KQLIREDENL QVPFLELHGE STEYVGRAEE
60 70 80 90 100
AIIALSNYRL HIKFKESLVN VPLQLIESVE CRDIFQLHLT CKDCKVIRCQ
110 120 130 140 150
FPTFEQCQDW LKRLNNAIRP PGKIEDLFSF AYHAWCMEVY ASEKEQHGDL
160 170 180 190 200
CRPGEHVTSR FKNEVERMGF DMNNAWRISN INEKYKLCGS YPQELIVPAW
210 220 230 240 250
ITDKELESVA GFRSWKRIPA VIYRHQSNGA VIARCGQPEV SWWGWRNADD
260 270 280 290 300
EHLVQSVARA CASDSQSSIS KVSTRNSCRD FPNAGDLSDV EFDSSLSNTS
310 320 330 340 350
GAESLALQPQ KLLILDARSY AAAVANRAKG GGCECPEYYP NCEVVFMGMA
360 370 380 390 400
NIHSIRRSFQ SLRLLCTQMP DPGNWLSALE STKWLHHLSV LLKSALLVVH
410 420 430 440 450
AVDRDQRPVL VHCSDGWDRT PQIVALAKLL LDPYYRTIEG FQVLVEMEWL
460 470 480 490 500
DFGHKFADRC GHGEDSDDLN ERCPVFLQWL DCVHQLQRQF PCSFEFNEAF
510 520 530 540 550
LVKLVQHTYS CLFGTFLCNN AKERGEKQTQ ERTCSVWSLL RAGNKAFKNL
560 570 580 590 600
LYSSQSEAVL YPVCHVRNLM LWSAVYLPCP SPSTPTDDSC APYPVPGTSP
610 620 630 640 650
DEPPLSRLPK TRSFDNLTTT CENMVPLASR RSSDPSLNEK WQEHGRSLEL
660 670 680 690 700
SSFASAGEEV PAMDSLRKPS RLLGGAELSV AAGVAEGQME NILQEATKEE
710 720 730 740 750
SGVEEPTHRG HTEVPEVKEE APLAKESSMA AEGPVVLYQE PQLDDATLRS
760 770 780 790 800
HQGPSLSLFS QGIPEHQDGH NVLSSSLQAP LRGEDSQEVP VEQPQVENIA
810 820 830 840 850
EDRENVAPAV PVDAKVGLGI SQSSSLLPSQ VPFETRGPHI NNSVHMLLED
860 870 880 890 900
KVKSESGPQL HHRPCPASSG RFSGKDMLPV APEPRSAERP QWDSVLHRTS
910 920 930 940 950
SPGNTLSLLQ APCALPLDKC RQGIVCNGAL ETENKASEQP AGFDTLQKYP
960 970 980 990 1000
TPNGHCANWE AGRSKDSLSH QLSATSCSSA HLYSRNLHHK WLNSHSGRPS
1010 1020 1030 1040 1050
TTSSPDQPSR SHLDDDGMPV YTDTIQQRLR QIESGHQQEV ETLKKQVQEL
1060 1070 1080 1090 1100
KSRLESQYLT SSLRFNGDFG DEVMTRWLPD HLAAHCYACD SAFWLASRKH
1110 1120 1130 1140 1150
HCRNCGNVFC SSCCNQKVPV PSQQLFEPSR VCKSCYSSLH PTSSSIDLEL

DKPIAATSN
Length:1,159
Mass (Da):129,679
Last modified:April 8, 2008 - v1
Checksum:i6F67F7679073F0B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606521 Genomic DNA. No translation available.
AL645910 Genomic DNA. No translation available.
BX323081 Genomic DNA. No translation available.
CH466574 Genomic DNA. Translation: EDL40479.1.
CH466574 Genomic DNA. Translation: EDL40481.1.
RefSeqiNP_083136.2. NM_028860.2.
UniGeneiMm.425669.

Genome annotation databases

EnsembliENSMUST00000040448; ENSMUSP00000049079; ENSMUSG00000034354.
ENSMUST00000109943; ENSMUSP00000105569; ENSMUSG00000034354.
GeneIDi74302.
KEGGimmu:74302.
UCSCiuc007hux.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiB1ATD5_MOUSE
AccessioniPrimary (citable) accession number: B1ATD5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 22, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported