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Protein
Submitted name:

Growth factor receptor-bound protein 2

Gene

Grb2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Growth factor receptor-bound protein 2Imported
Gene namesi
Name:Grb2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:95805. Grb2.

PTM / Processingi

Proteomic databases

MaxQBiB1AT92.
PeptideAtlasiB1AT92.
PRIDEiB1AT92.

Expressioni

Gene expression databases

BgeeiENSMUSG00000059923.
ExpressionAtlasiB1AT92. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiB1AT92. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliB1AT92.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 58SH3InterPro annotationAdd BLAST58
Domaini60 – 152SH2InterPro annotationAdd BLAST93
Domaini148 – 201SH3InterPro annotationAdd BLAST54

Sequence similaritiesi

Contains 2 SH3 domains.UniRule annotation

Keywords - Domaini

SH3 domainUniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00820000126999.
HOGENOMiHOG000251625.
HOVERGENiHBG005404.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00017. SH2. 1 hit.
PF00018. SH3_1. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
PR00452. SH3DOMAIN.
SMARTiSM00252. SH2. 1 hit.
SM00326. SH3. 2 hits.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
PS50002. SH3. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1AT92-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK
60 70 80 90 100
NYIEMKPHPW FFGKIPRAKA EEMLSKQRHD GAFLIRESES APGDFSLSVK
110 120 130 140 150
FGNDVQHFKV LRDGAGKYFL WVVKFNSLNE LVDYHRSTSV SRNQQIFLRD
160 170 180 190 200
IEQMPQEDGE LGFRRGDFIH VMDNSDPNWW KGACHGQTGM FPRNYVTPVN

RNV
Length:203
Mass (Da):23,588
Last modified:April 8, 2008 - v1
Checksum:i8FA4969BF34F6CF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645852 Genomic DNA. No translation available.
AL732491 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000106495; ENSMUSP00000102104; ENSMUSG00000059923.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645852 Genomic DNA. No translation available.
AL732491 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliB1AT92.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB1AT92. 1 interactor.

Proteomic databases

MaxQBiB1AT92.
PeptideAtlasiB1AT92.
PRIDEiB1AT92.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000106495; ENSMUSP00000102104; ENSMUSG00000059923.

Organism-specific databases

MGIiMGI:95805. Grb2.

Phylogenomic databases

GeneTreeiENSGT00820000126999.
HOGENOMiHOG000251625.
HOVERGENiHBG005404.

Miscellaneous databases

ChiTaRSiGrb2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000059923.
ExpressionAtlasiB1AT92. baseline and differential.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00017. SH2. 1 hit.
PF00018. SH3_1. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
PR00452. SH3DOMAIN.
SMARTiSM00252. SH2. 1 hit.
SM00326. SH3. 2 hits.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
PS50002. SH3. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB1AT92_MOUSE
AccessioniPrimary (citable) accession number: B1AT92
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 30, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.