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B1ASC0

- B1ASC0_MOUSE

UniProt

B1ASC0 - B1ASC0_MOUSE

Protein
Submitted name:

Brain-specific angiogenesis inhibitor 2

Gene

Bai2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 2 (10 Jun 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. G-protein coupled receptor activity Source: InterPro

    GO - Biological processi

    1. negative regulation of angiogenesis Source: InterPro
    2. neuropeptide signaling pathway Source: InterPro
    3. peripheral nervous system development Source: MGI

    Protein family/group databases

    MEROPSiS63.032.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Brain-specific angiogenesis inhibitor 2Imported
    Gene namesi
    Name:Bai2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 4

    Organism-specific databases

    MGIiMGI:2451244. Bai2.

    Subcellular locationi

    Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membraneSAAS annotation, Membrane

    Structurei

    3D structure databases

    ProteinModelPortaliB1ASC0.
    SMRiB1ASC0. Positions 300-860, 883-1116.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains GPS domain.SAAS annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00690000101769.
    HOGENOMiHOG000230916.
    HOVERGENiHBG004813.
    OrthoDBiEOG7KDF90.

    Family and domain databases

    InterProiIPR022624. DUF3497.
    IPR017981. GPCR_2-like.
    IPR008077. GPCR_2_brain-spec_angio_inhib.
    IPR001879. GPCR_2_extracellular_dom.
    IPR000832. GPCR_2_secretin-like.
    IPR000203. GPS.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view]
    PfamiPF00002. 7tm_2. 1 hit.
    PF12003. DUF3497. 1 hit.
    PF01825. GPS. 1 hit.
    PF02793. HRM. 1 hit.
    PF00090. TSP_1. 3 hits.
    [Graphical view]
    PRINTSiPR01694. BAIPRECURSOR.
    PR00249. GPCRSECRETIN.
    SMARTiSM00303. GPS. 1 hit.
    SM00008. HormR. 1 hit.
    SM00209. TSP1. 3 hits.
    [Graphical view]
    SUPFAMiSSF82895. SSF82895. 3 hits.
    PROSITEiPS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    PS50221. GPS. 1 hit.
    PS50092. TSP1. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1ASC0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTPACPLLLS VILSLRLATA FDPAPSACSA LASGVLYGAF SLQDLFPTIA     50
    SGCSWTLENP DPTKYSLYLR FNRQEQVCTH FAPRLLPLDH YLVNFTCLRP 100
    GPEEATARAE SEVGRPEEEE EEAAAAASGL ELCGGSGPFT FLHFDKNFVQ 150
    LCLSAEPSEA PRLLAPAALA FRFVEVLLIN NNNSSQFTCG VLCRWSEECG 200
    RAAGRACGFA QPGCSCPGEA GANPATTTSP GPPVAHTLSN ALVPGGPAPP 250
    AEADLHSGSS NDLFTTEMRY GEEPEEEPKV KTQWPRSADE PGLYMAQTGD 300
    PAAEEWSPWS VCSLTCGQGL QVRTRSCVSS PYGTLCSGPL RETRPCNNSA 350
    TCPVEGQWLE WGPWGPCSSS CANGTQQRSR KCSVAGPAWA TCAGALTDTR 400
    ECSNLDCPAT DGKWGPWNAW SLCSKTCDTG WQRRFRMCQA SGTQGYPCEG 450
    TGEEVKPCSE KRCPAFHEMC RDEYVMLMTW KRAAAGEIIY NKCPPNASGS 500
    ASRRCLLSAQ GVAYWGLPSF ARCISHEYRY LYLSLREHLA KGQRMLAGEG 550
    MSQVVRSLQE LLARRTYYSG DLLFSVDILR NVTDTFKRAT YVPSADDVQR 600
    FFQVVSFMVD SENKDKWDDA QQVSPGSVHL LRVVEDFIHL VGDALKAFQS 650
    SLIVTDNLVI SIQREPISAV SSDITFPMRG RRGMKDWVRH SEDRLFLPKE 700
    VLSLSSPGKP ATPGAATAGS PGRGRGPGTV PPGPGHAHQR LLPADPEESS 750
    SYFVIGAVLY RTLGLILPPP RPPLAVTSRV MTVTVRPPTQ PPAEPLITVE 800
    LSYIINGTTD PHCASWDYSR ADTNSGDWNT ESCQTLETQA AHTRCQCQHL 850
    STFAVLAQPP KDLTLELAGA PSVPLVIGCA VSCMALLTLL AIYAAFWRFI 900
    KSERSIILLN FCLSILASNI LILVGQSRVL SKGVCTMTAA FLHFFFLSSF 950
    CWVLTEAWQS YLAVIGRMRT RLVRKRFLCL GWGLPALVVA VSVGFTRTKG 1000
    YGTSSYCWLS LEGGLLYAFV GPAAVIVLVN MLIGIIVFNK LMARDGVSDK 1050
    SKKQRAGASL WSSCVVLPLL ALTWMSAVLA MTDRRSVLFQ ALFAVFNSAQ 1100
    GFVITAVHCF LRREVQDVVK CQMGVCRADE SEDSPDSCKN GQLQILSDFE 1150
    KDVDLACQTV LFKEVNTCNP STITGTLSRL SLDEDEEPKS CLVGPEGGLS 1200
    FSPLPGNILV PMAASPGLGE PPPPQETNPV YMCGEGGLRQ LDLTWIRQSE 1250
    PGSEGDYMVL PRRTLSLQPG GGGTAGEEAP RARPEGTPRR AAKTVAHTEG 1300
    YPSFLSVEHS GLGLGPAYGS LQNPYGMTFQ PPPPTPSARQ VPEPGERSRT 1350
    MPRTVPGSTM KLGSLERKKL RYSDLDFEKV MHTRKRHSEL YHELNQKFHT 1400
    FDRYRSQSSA KEKPSPPGGR PGLSQHRRHQ SWSTFKSMTL GSLPPKPRER 1450
    LALHRTAAWE PTEPPDGDFQ TEV 1473
    Length:1,473
    Mass (Da):160,560
    Last modified:June 10, 2008 - v2
    Checksum:i0E5F31A92BFA39B4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL626774 Genomic DNA. No translation available.
    RefSeqiNP_001277643.1. NM_001290714.1.
    UniGeneiMm.262241.

    Genome annotation databases

    EnsembliENSMUST00000120204; ENSMUSP00000112524; ENSMUSG00000028782.
    GeneIDi230775.
    UCSCiuc008uyo.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL626774 Genomic DNA. No translation available.
    RefSeqi NP_001277643.1. NM_001290714.1.
    UniGenei Mm.262241.

    3D structure databases

    ProteinModelPortali B1ASC0.
    SMRi B1ASC0. Positions 300-860, 883-1116.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi S63.032.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000120204 ; ENSMUSP00000112524 ; ENSMUSG00000028782 .
    GeneIDi 230775.
    UCSCi uc008uyo.2. mouse.

    Organism-specific databases

    MGIi MGI:2451244. Bai2.

    Phylogenomic databases

    GeneTreei ENSGT00690000101769.
    HOGENOMi HOG000230916.
    HOVERGENi HBG004813.
    OrthoDBi EOG7KDF90.

    Miscellaneous databases

    ChiTaRSi BAI2. mouse.
    NextBioi 35545811.
    SOURCEi Search...

    Family and domain databases

    InterProi IPR022624. DUF3497.
    IPR017981. GPCR_2-like.
    IPR008077. GPCR_2_brain-spec_angio_inhib.
    IPR001879. GPCR_2_extracellular_dom.
    IPR000832. GPCR_2_secretin-like.
    IPR000203. GPS.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view ]
    Pfami PF00002. 7tm_2. 1 hit.
    PF12003. DUF3497. 1 hit.
    PF01825. GPS. 1 hit.
    PF02793. HRM. 1 hit.
    PF00090. TSP_1. 3 hits.
    [Graphical view ]
    PRINTSi PR01694. BAIPRECURSOR.
    PR00249. GPCRSECRETIN.
    SMARTi SM00303. GPS. 1 hit.
    SM00008. HormR. 1 hit.
    SM00209. TSP1. 3 hits.
    [Graphical view ]
    SUPFAMi SSF82895. SSF82895. 3 hits.
    PROSITEi PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    PS50221. GPS. 1 hit.
    PS50092. TSP1. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
      Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.
      J. Proteome Res. 7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (JUN-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiB1ASC0_MOUSE
    AccessioniPrimary (citable) accession number: B1ASC0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: June 10, 2008
    Last modified: October 1, 2014
    This is version 56 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3