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Protein
Submitted name:

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

Gene

Pik3cd

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. 1-phosphatidylinositol-3-kinase activity Source: GO_Central
  2. 1-phosphatidylinositol-4-phosphate 3-kinase activity Source: GO_Central
  3. phosphatidylinositol-4,5-bisphosphate 3-kinase activity Source: GO_Central

GO - Biological processi

  1. B cell activation Source: MGI
  2. B cell homeostasis Source: MGI
  3. cell surface receptor signaling pathway Source: MGI
  4. phosphatidylinositol-3-phosphate biosynthetic process Source: GOC
  5. phosphatidylinositol-mediated signaling Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformImported
Gene namesi
Name:Pik3cdImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:1098211. Pik3cd.

Subcellular locationi

GO - Cellular componenti

  1. phosphatidylinositol 3-kinase complex Source: GO_Central
  2. plasma membrane Source: GO_Central
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiB1AS27. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000101315.

Structurei

3D structure databases

ProteinModelPortaliB1AS27.
SMRiB1AS27. Positions 14-62.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119110.

Family and domain databases

InterProiIPR003113. PI3K_adapt-bd_dom.
IPR015433. PI_Kinase.
[Graphical view]
PANTHERiPTHR10048. PTHR10048. 1 hit.
PfamiPF02192. PI3K_p85B. 1 hit.
[Graphical view]
PROSITEiPS51544. PI3K_ABD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B1AS27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPGVDCPME FWTKEESQSV VVDFLLPTGV YLNFPVSRNA NLSTIKQVLW
60
HRAQYEPLFH ML
Length:62
Mass (Da):7,208
Last modified:April 8, 2008 - v1
Checksum:i8B79D2970F2DC01B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei62 – 621Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL607078 Genomic DNA. No translation available.
AL626808 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000134534; ENSMUSP00000118988; ENSMUSG00000039936.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL607078 Genomic DNA. No translation available.
AL626808 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliB1AS27.
SMRiB1AS27. Positions 14-62.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000101315.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000134534; ENSMUSP00000118988; ENSMUSG00000039936.

Organism-specific databases

MGIiMGI:1098211. Pik3cd.

Phylogenomic databases

GeneTreeiENSGT00760000119110.

Miscellaneous databases

ChiTaRSiPik3cd. mouse.
NextBioi35545786.
SOURCEiSearch...

Gene expression databases

ExpressionAtlasiB1AS27. baseline and differential.

Family and domain databases

InterProiIPR003113. PI3K_adapt-bd_dom.
IPR015433. PI_Kinase.
[Graphical view]
PANTHERiPTHR10048. PTHR10048. 1 hit.
PfamiPF02192. PI3K_p85B. 1 hit.
[Graphical view]
PROSITEiPS51544. PI3K_ABD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB1AS27_MOUSE
AccessioniPrimary (citable) accession number: B1AS27
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: February 4, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.