ID   B1AS25_MOUSE            Unreviewed;       171 AA.
AC   B1AS25;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 101.
DE   SubName: Full=Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta {ECO:0000313|Ensembl:ENSMUSP00000119858.2};
DE   Flags: Fragment;
GN   Name=Pik3cd {ECO:0000313|Ensembl:ENSMUSP00000119858.2,
GN   ECO:0000313|MGI:MGI:1098211};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000119858.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000119858.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119858.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000119858.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119858.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00877}.
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DR   AlphaFoldDB; B1AS25; -.
DR   SMR; B1AS25; -.
DR   MaxQB; B1AS25; -.
DR   PeptideAtlas; B1AS25; -.
DR   ProteomicsDB; 306648; -.
DR   Antibodypedia; 4215; 677 antibodies from 38 providers.
DR   Ensembl; ENSMUST00000127273.8; ENSMUSP00000119858.2; ENSMUSG00000039936.19.
DR   AGR; MGI:1098211; -.
DR   MGI; MGI:1098211; Pik3cd.
DR   VEuPathDB; HostDB:ENSMUSG00000039936; -.
DR   GeneTree; ENSGT00940000159079; -.
DR   OMA; CCEPQIT; -.
DR   ChiTaRS; Pik3cd; mouse.
DR   Proteomes; UP000000589; Chromosome 4.
DR   Bgee; ENSMUSG00000039936; Expressed in granulocyte and 170 other cell types or tissues.
DR   ExpressionAtlas; B1AS25; baseline and differential.
DR   Gene3D; 3.10.20.770; -; 1.
DR   InterPro; IPR003113; PI3K_ABD.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   Pfam; PF02192; PI3K_p85B; 1.
DR   SMART; SM00143; PI3K_p85B; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS51544; PI3K_ABD; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:B1AS25,
KW   ECO:0007829|MaxQB:B1AS25};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   DOMAIN          16..105
FT                   /note="PI3K-ABD"
FT                   /evidence="ECO:0000259|PROSITE:PS51544"
FT   NON_TER         171
FT                   /evidence="ECO:0000313|Ensembl:ENSMUSP00000119858.2"
SQ   SEQUENCE   171 AA;  20011 MW;  120DB379934E65E5 CRC64;
     MPPGVDCPME FWTKEESQSV VVDFLLPTGV YLNFPVSRNA NLSTIKQVLW HRAQYEPLFH
     MLSDPEAYVF TCVNQTAEQQ ELEDEQRRLC DIQPFLPVLR LVAREGDRVK KLINSQISLL
     IGKGLHEFDS LRDPEVNDFR TKMRQFCEEA AAHRQQLGWV EWLQYSFPLQ L
//