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Protein
Submitted name:

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

Gene

Pik3cd

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • adaptive immune response Source: GO_Central
  • B cell activation Source: MGI
  • B cell homeostasis Source: MGI
  • cell chemotaxis Source: GO_Central
  • cell surface receptor signaling pathway Source: MGI
  • defense response to fungus Source: MGI
  • homeostasis of number of cells Source: MGI
  • inflammatory response Source: GO_Central
  • innate immune response Source: GO_Central
  • phosphatidylinositol 3-kinase signaling Source: GO_Central
  • phosphatidylinositol-3-phosphate biosynthetic process Source: GO_Central
  • phosphatidylinositol phosphorylation Source: GO_Central
  • platelet activation Source: GO_Central
  • positive regulation of cell migration Source: MGI
  • positive regulation of gene expression Source: MGI
  • protein phosphorylation Source: GO_Central
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformImported
Gene namesi
Name:Pik3cdImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1098211. Pik3cd.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiB1AS24.
ExpressionAtlasiB1AS24. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000101315.

Structurei

3D structure databases

ProteinModelPortaliB1AS24.
SMRiB1AS24. Positions 14-145.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119110.
HOGENOMiHOG000200034.
HOVERGENiHBG095786.

Family and domain databases

InterProiIPR003113. PI3K_adapt-bd_dom.
IPR015433. PI_Kinase.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR10048. PTHR10048. 1 hit.
PfamiPF02192. PI3K_p85B. 1 hit.
[Graphical view]
SMARTiSM00143. PI3K_p85B. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
PROSITEiPS51544. PI3K_ABD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B1AS24-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPGVDCPME FWTKEESQSV VVDFLLPTGV YLNFPVSRNA NLSTIKQVLW
60 70 80 90 100
HRAQYEPLFH MLSDPEAYVF TCVNQTAEQQ ELEDEQRRLC DIQPFLPVLR
110 120 130 140
LVAREGDRVK KLINSQISLL IGKGLHEFDS LRDPEVNDFR TKMRQ
Length:145
Mass (Da):16,878
Last modified:April 8, 2008 - v1
Checksum:iBF2CB69A62C85913
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei145 – 1451Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL607078 Genomic DNA. No translation available.
AL626808 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000131224; ENSMUSP00000115542; ENSMUSG00000039936.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL607078 Genomic DNA. No translation available.
AL626808 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliB1AS24.
SMRiB1AS24. Positions 14-145.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000101315.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000131224; ENSMUSP00000115542; ENSMUSG00000039936.

Organism-specific databases

MGIiMGI:1098211. Pik3cd.

Phylogenomic databases

GeneTreeiENSGT00760000119110.
HOGENOMiHOG000200034.
HOVERGENiHBG095786.

Miscellaneous databases

ChiTaRSiPik3cd. mouse.
NextBioi35545783.
SOURCEiSearch...

Gene expression databases

BgeeiB1AS24.
ExpressionAtlasiB1AS24. baseline and differential.

Family and domain databases

InterProiIPR003113. PI3K_adapt-bd_dom.
IPR015433. PI_Kinase.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR10048. PTHR10048. 1 hit.
PfamiPF02192. PI3K_p85B. 1 hit.
[Graphical view]
SMARTiSM00143. PI3K_p85B. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
PROSITEiPS51544. PI3K_ABD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB1AS24_MOUSE
AccessioniPrimary (citable) accession number: B1AS24
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: June 24, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.