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B1ARM8

- B1ARM8_MOUSE

UniProt

B1ARM8 - B1ARM8_MOUSE

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Protein
Submitted name:

Abnormal spindle-like microcephaly-associated protein homolog

Gene

Aspm

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. calmodulin binding Source: MGI

GO - Biological processi

  1. brain development Source: MGI
  2. cerebral cortex development Source: MGI
  3. developmental growth Source: MGI
  4. forebrain neuroblast division Source: MGI
  5. maintenance of centrosome location Source: MGI
  6. male gonad development Source: MGI
  7. negative regulation of asymmetric cell division Source: MGI
  8. negative regulation of neuron differentiation Source: MGI
  9. neuronal stem cell maintenance Source: MGI
  10. neuron migration Source: MGI
  11. oogenesis Source: MGI
  12. positive regulation of canonical Wnt signaling pathway Source: MGI
  13. positive regulation of neuroblast proliferation Source: MGI
  14. spermatogenesis Source: MGI
  15. spindle assembly involved in meiosis Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Abnormal spindle-like microcephaly-associated protein homologImported
Gene namesi
Name:AspmImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 1

Organism-specific databases

MGIiMGI:1334448. Aspm.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. meiotic spindle Source: MGI
  3. microtubule Source: MGI
  4. midbody Source: MGI
  5. mitotic spindle pole Source: MGI
  6. spindle pole Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB1ARM8.

Expressioni

Gene expression databases

BgeeiB1ARM8.
ExpressionAtlasiB1ARM8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB1ARM8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00560000077332.
HOGENOMiHOG000034105.
HOVERGENiHBG080092.
KOiK16743.

Family and domain databases

Gene3Di1.10.418.10. 3 hits.
InterProiIPR016024. ARM-type_fold.
IPR022613. CAMSAP_CH.
IPR001715. CH-domain.
IPR000048. IQ_motif_EF-hand-BS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF11971. CAMSAP_CH. 1 hit.
PF00612. IQ. 7 hits.
[Graphical view]
SMARTiSM00033. CH. 2 hits.
SM00015. IQ. 13 hits.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 3 hits.
SSF48371. SSF48371. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS50021. CH. 2 hits.
PS50096. IQ. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1ARM8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATMQAASCP EERGRRARPD PEAGDPSPPV LLLSHFCGVP FLCFGDVRVG
60 70 80 90 100
TSRTRSLVLH NPHEEPLQVE LSLLRAAGQG FSVAPNRCEL KPKEKLTISV
110 120 130 140 150
TWTPLREGGV REIVTFLVND FLKHQAILLG NAEEPKKKKR SLWNTSKKIP
160 170 180 190 200
ASSKHTKRTS KNQHFNESFT ISQKDRIRSP LQPCENLAMS ECSSPTENKV
210 220 230 240 250
PTPSISPIRE CQSETCLPLF LRESTAYSSL HESENTQNLK VQDASISQTF
260 270 280 290 300
DFNEEVANET FINPISVCHQ SEGDRKLTLA PNCSSPLNST QTQIHFLSPD
310 320 330 340 350
SFVNNRYTSD NDLKSMKNVL SDTFRKDPAE SVCLESQTVH EVCQTILSPD
360 370 380 390 400
SFLNDNYGLK KGLNFKSVNP VLSPTQFVKD SMGHVGQQTG KSNEASQDWR
410 420 430 440 450
INEGLAYTPE CQHAQTPSSR SEKQNPVEVK PHTYDFTKQK PKISEFQDAF
460 470 480 490 500
CHQSKQPHKR RPILSATVTK RKPTNAREKL PEINKPDAKR CLEGLVGERG
510 520 530 540 550
KEVGSLREKG FHSSLPVVEP GVSKALSYRD EVTPATVVVA RKRKSHGTVG
560 570 580 590 600
DANGKVAAEE WMDMCEVKRI HFSPLESTPS TVARTTKKEG HTSKRISSLE
610 620 630 640 650
RSGLKKKMDS SILKTPLSKT KKKRRSIVAV AQSHLTFIKP LKAAIPRHPM
660 670 680 690 700
PFAAKNMFYD ERWKEKQEQG FTWWLNYILT PDDFTVKTNV SKVNAASLVL
710 720 730 740 750
GAESQHKISV PKAPTKEEVS LRAYTASCRL NRLRRTACSL FTSEKMVKAI
760 770 780 790 800
KKVEIEIEVG RLLVRKDRHL WKDIGQRQKV LNWLLSYNPL WLRIGLETVF
810 820 830 840 850
GELIPLADNS DVTGLAMFIL NRLLWNPDIA AEYRHPTVPL LFRDGHEAAL
860 870 880 890 900
SKFTLKKLLL LICFLDHAKI SRLIDHDPCL FCKDAEFKAS KELLLAFSRD
910 920 930 940 950
FLSGEGDLSR HLSFLGLPVS HVQTPLDEFD FAVTNLAVDL QCGVRLVRTV
960 970 980 990 1000
ELLTQNWNLS DKLRIPAISR VQKMHNVDLV LQVLKSRGVP LTDEHGSAIS
1010 1020 1030 1040 1050
SKDVVDRHRE KTLGLLWKIA LAFQVDISLN LDQLKEEIDF LKHTHSIKRA
1060 1070 1080 1090 1100
MSALTCPSQA ITNKQRDKRI SGNFERYGDS VQLLMDWVNA VCAFYNKKVE
1110 1120 1130 1140 1150
NFTVSFSDGR ILCYLIHHYH PCYVPFDAIC QRTSQSVACA QTGSVVLNSS
1160 1170 1180 1190 1200
SESEGGCLDL SLEALDHEST PEMYKELLEN EKKNFHLVRS AARDLGGIPA
1210 1220 1230 1240 1250
MIHHSDMSNT IPDEKVVITY LSFLCARLLD LRKEIRAARL IQTTWRKYKL
1260 1270 1280 1290 1300
KRDLKHHQER DKAARVIQSV VLNFLSRRRL QKNVSAALVI QKCWRRVSAQ
1310 1320 1330 1340 1350
RKLRMLKNEK LAKLQNKSAV LIQAGCRKYK AKKYLSKVEA ACRIQAWYRR
1360 1370 1380 1390 1400
WRAHKKYLTL LKAVNIIEGY LSAQLARRRF LKMRAAAIII QRKWRATLSV
1410 1420 1430 1440 1450
RGARENLKRH RAACVIQAHF RGYQARQSFL QQRSAVLIIQ RHVRAMVAAK
1460 1470 1480 1490 1500
QERIKYIKLK KSTVVVQALV RGWLVRKRVS EQKAKTRLFH FTAAAYCHMC
1510 1520 1530 1540 1550
ALKIQRAYRL HVTLRNAKKH MDSVIFIQRW FRKRLQRKRF IEQYHKILST
1560 1570 1580 1590 1600
RREAHACWLQ QDRAASVIQK AVRRFLLCRR QEKITSCATR IQALWRGYSW
1610 1620 1630 1640 1650
RKKNDHTEIK AIRRSLRAVS TTVEEENKLY RRTERALHHL LTYKHLSAIL
1660 1670 1680 1690 1700
DALKHLEVVT RLSPLCCENM AESGAVSTIF VVIRSCNRSV PCMEVVGYAV
1710 1720 1730 1740 1750
QVLLNVAKYD KTIAAVYEAE NCVDTLLELL QVYREKPGDR VAEKSASIFT
1760 1770 1780 1790 1800
RTCCLLAVLL KTEQCAFDAQ SRSKVTDRIY RLYKFTVPKH KVNTQGLFDK
1810 1820 1830 1840 1850
QKQNSCVGFP CIPERTMKTR LVSRLKPQWV LRRDNVEEIT NSLQAIQLVM

DTLGISY
Length:1,857
Mass (Da):212,056
Last modified:April 8, 2008 - v1
Checksum:iF3B2F3FE8E8C4DA2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC158946 Genomic DNA. No translation available.
AL606536 Genomic DNA. No translation available.
RefSeqiXP_006529173.1. XM_006529110.1.
UniGeneiMm.168523.

Genome annotation databases

EnsembliENSMUST00000097554; ENSMUSP00000095162; ENSMUSG00000033952.
GeneIDi12316.
KEGGimmu:12316.
UCSCiuc007cwi.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC158946 Genomic DNA. No translation available.
AL606536 Genomic DNA. No translation available.
RefSeqi XP_006529173.1. XM_006529110.1.
UniGenei Mm.168523.

3D structure databases

ProteinModelPortali B1ARM8.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B1ARM8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000097554 ; ENSMUSP00000095162 ; ENSMUSG00000033952 .
GeneIDi 12316.
KEGGi mmu:12316.
UCSCi uc007cwi.1. mouse.

Organism-specific databases

CTDi 259266.
MGIi MGI:1334448. Aspm.

Phylogenomic databases

GeneTreei ENSGT00560000077332.
HOGENOMi HOG000034105.
HOVERGENi HBG080092.
KOi K16743.

Miscellaneous databases

NextBioi 35545739.
SOURCEi Search...

Gene expression databases

Bgeei B1ARM8.
ExpressionAtlasi B1ARM8. baseline and differential.

Family and domain databases

Gene3Di 1.10.418.10. 3 hits.
InterProi IPR016024. ARM-type_fold.
IPR022613. CAMSAP_CH.
IPR001715. CH-domain.
IPR000048. IQ_motif_EF-hand-BS.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF11971. CAMSAP_CH. 1 hit.
PF00612. IQ. 7 hits.
[Graphical view ]
SMARTi SM00033. CH. 2 hits.
SM00015. IQ. 13 hits.
[Graphical view ]
SUPFAMi SSF47576. SSF47576. 3 hits.
SSF48371. SSF48371. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEi PS50021. CH. 2 hits.
PS50096. IQ. 6 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB1ARM8_MOUSE
AccessioniPrimary (citable) accession number: B1ARM8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 29, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3