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B1ARM8

- B1ARM8_MOUSE

UniProt

B1ARM8 - B1ARM8_MOUSE

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Protein
Submitted name: Abnormal spindle-like microcephaly-associated protein homolog
Gene
Aspm
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5 - Protein predictedi

Functioni

GO - Biological processi

  1. brain development Source: MGI
  2. developmental growth Source: MGI
  3. forebrain neuroblast division Source: MGI
  4. maintenance of centrosome location Source: MGI
  5. negative regulation of asymmetric cell division Source: MGI
  6. negative regulation of neuron differentiation Source: MGI
  7. neuron migration Source: MGI
  8. oogenesis Source: MGI
  9. positive regulation of canonical Wnt signaling pathway Source: MGI
  10. positive regulation of neuroblast proliferation Source: MGI
  11. spermatogenesis Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Abnormal spindle-like microcephaly-associated protein homologImported
Gene namesi
Name:AspmImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 1

Organism-specific databases

MGIiMGI:1334448. Aspm.

Subcellular locationi

GO - Cellular componenti

  1. midbody Source: MGI
  2. spindle pole Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB1ARM8.

Expressioni

Gene expression databases

ArrayExpressiB1ARM8.
BgeeiB1ARM8.

Structurei

3D structure databases

ProteinModelPortaliB1ARM8.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00560000077332.
HOGENOMiHOG000034105.
HOVERGENiHBG080092.
KOiK16743.

Family and domain databases

Gene3Di1.10.418.10. 3 hits.
InterProiIPR016024. ARM-type_fold.
IPR022613. CAMSAP_CH.
IPR001715. CH-domain.
IPR000048. IQ_motif_EF-hand-BS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF11971. CAMSAP_CH. 1 hit.
PF00612. IQ. 7 hits.
[Graphical view]
SMARTiSM00033. CH. 2 hits.
SM00015. IQ. 13 hits.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 3 hits.
SSF48371. SSF48371. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS50021. CH. 2 hits.
PS50096. IQ. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1ARM8-1 [UniParc]FASTAAdd to Basket

« Hide

MATMQAASCP EERGRRARPD PEAGDPSPPV LLLSHFCGVP FLCFGDVRVG     50
TSRTRSLVLH NPHEEPLQVE LSLLRAAGQG FSVAPNRCEL KPKEKLTISV 100
TWTPLREGGV REIVTFLVND FLKHQAILLG NAEEPKKKKR SLWNTSKKIP 150
ASSKHTKRTS KNQHFNESFT ISQKDRIRSP LQPCENLAMS ECSSPTENKV 200
PTPSISPIRE CQSETCLPLF LRESTAYSSL HESENTQNLK VQDASISQTF 250
DFNEEVANET FINPISVCHQ SEGDRKLTLA PNCSSPLNST QTQIHFLSPD 300
SFVNNRYTSD NDLKSMKNVL SDTFRKDPAE SVCLESQTVH EVCQTILSPD 350
SFLNDNYGLK KGLNFKSVNP VLSPTQFVKD SMGHVGQQTG KSNEASQDWR 400
INEGLAYTPE CQHAQTPSSR SEKQNPVEVK PHTYDFTKQK PKISEFQDAF 450
CHQSKQPHKR RPILSATVTK RKPTNAREKL PEINKPDAKR CLEGLVGERG 500
KEVGSLREKG FHSSLPVVEP GVSKALSYRD EVTPATVVVA RKRKSHGTVG 550
DANGKVAAEE WMDMCEVKRI HFSPLESTPS TVARTTKKEG HTSKRISSLE 600
RSGLKKKMDS SILKTPLSKT KKKRRSIVAV AQSHLTFIKP LKAAIPRHPM 650
PFAAKNMFYD ERWKEKQEQG FTWWLNYILT PDDFTVKTNV SKVNAASLVL 700
GAESQHKISV PKAPTKEEVS LRAYTASCRL NRLRRTACSL FTSEKMVKAI 750
KKVEIEIEVG RLLVRKDRHL WKDIGQRQKV LNWLLSYNPL WLRIGLETVF 800
GELIPLADNS DVTGLAMFIL NRLLWNPDIA AEYRHPTVPL LFRDGHEAAL 850
SKFTLKKLLL LICFLDHAKI SRLIDHDPCL FCKDAEFKAS KELLLAFSRD 900
FLSGEGDLSR HLSFLGLPVS HVQTPLDEFD FAVTNLAVDL QCGVRLVRTV 950
ELLTQNWNLS DKLRIPAISR VQKMHNVDLV LQVLKSRGVP LTDEHGSAIS 1000
SKDVVDRHRE KTLGLLWKIA LAFQVDISLN LDQLKEEIDF LKHTHSIKRA 1050
MSALTCPSQA ITNKQRDKRI SGNFERYGDS VQLLMDWVNA VCAFYNKKVE 1100
NFTVSFSDGR ILCYLIHHYH PCYVPFDAIC QRTSQSVACA QTGSVVLNSS 1150
SESEGGCLDL SLEALDHEST PEMYKELLEN EKKNFHLVRS AARDLGGIPA 1200
MIHHSDMSNT IPDEKVVITY LSFLCARLLD LRKEIRAARL IQTTWRKYKL 1250
KRDLKHHQER DKAARVIQSV VLNFLSRRRL QKNVSAALVI QKCWRRVSAQ 1300
RKLRMLKNEK LAKLQNKSAV LIQAGCRKYK AKKYLSKVEA ACRIQAWYRR 1350
WRAHKKYLTL LKAVNIIEGY LSAQLARRRF LKMRAAAIII QRKWRATLSV 1400
RGARENLKRH RAACVIQAHF RGYQARQSFL QQRSAVLIIQ RHVRAMVAAK 1450
QERIKYIKLK KSTVVVQALV RGWLVRKRVS EQKAKTRLFH FTAAAYCHMC 1500
ALKIQRAYRL HVTLRNAKKH MDSVIFIQRW FRKRLQRKRF IEQYHKILST 1550
RREAHACWLQ QDRAASVIQK AVRRFLLCRR QEKITSCATR IQALWRGYSW 1600
RKKNDHTEIK AIRRSLRAVS TTVEEENKLY RRTERALHHL LTYKHLSAIL 1650
DALKHLEVVT RLSPLCCENM AESGAVSTIF VVIRSCNRSV PCMEVVGYAV 1700
QVLLNVAKYD KTIAAVYEAE NCVDTLLELL QVYREKPGDR VAEKSASIFT 1750
RTCCLLAVLL KTEQCAFDAQ SRSKVTDRIY RLYKFTVPKH KVNTQGLFDK 1800
QKQNSCVGFP CIPERTMKTR LVSRLKPQWV LRRDNVEEIT NSLQAIQLVM 1850
DTLGISY 1857
Length:1,857
Mass (Da):212,056
Last modified:April 8, 2008 - v1
Checksum:iF3B2F3FE8E8C4DA2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC158946 Genomic DNA. No translation available.
AL606536 Genomic DNA. No translation available.
RefSeqiXP_006529173.1. XM_006529110.1.
UniGeneiMm.168523.

Genome annotation databases

EnsembliENSMUST00000097554; ENSMUSP00000095162; ENSMUSG00000033952.
GeneIDi12316.
KEGGimmu:12316.
UCSCiuc007cwi.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC158946 Genomic DNA. No translation available.
AL606536 Genomic DNA. No translation available.
RefSeqi XP_006529173.1. XM_006529110.1.
UniGenei Mm.168523.

3D structure databases

ProteinModelPortali B1ARM8.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B1ARM8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000097554 ; ENSMUSP00000095162 ; ENSMUSG00000033952 .
GeneIDi 12316.
KEGGi mmu:12316.
UCSCi uc007cwi.1. mouse.

Organism-specific databases

CTDi 259266.
MGIi MGI:1334448. Aspm.

Phylogenomic databases

GeneTreei ENSGT00560000077332.
HOGENOMi HOG000034105.
HOVERGENi HBG080092.
KOi K16743.

Miscellaneous databases

NextBioi 35545739.
SOURCEi Search...

Gene expression databases

ArrayExpressi B1ARM8.
Bgeei B1ARM8.

Family and domain databases

Gene3Di 1.10.418.10. 3 hits.
InterProi IPR016024. ARM-type_fold.
IPR022613. CAMSAP_CH.
IPR001715. CH-domain.
IPR000048. IQ_motif_EF-hand-BS.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF11971. CAMSAP_CH. 1 hit.
PF00612. IQ. 7 hits.
[Graphical view ]
SMARTi SM00033. CH. 2 hits.
SM00015. IQ. 13 hits.
[Graphical view ]
SUPFAMi SSF47576. SSF47576. 3 hits.
SSF48371. SSF48371. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEi PS50021. CH. 2 hits.
PS50096. IQ. 6 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB1ARM8_MOUSE
AccessioniPrimary (citable) accession number: B1ARM8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: July 9, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi