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Protein
Submitted name:

Very long-chain-specific acyl-CoA dehydrogenase, mitochondrial

Gene

Acadvl

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Names & Taxonomyi

Protein namesi
Submitted name:
Very long-chain-specific acyl-CoA dehydrogenase, mitochondrialImported
Gene namesi
Name:AcadvlImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:895149. Acadvl.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiB1AR28.
PaxDbiB1AR28.
PeptideAtlasiB1AR28.
PRIDEiB1AR28.

Expressioni

Gene expression databases

BgeeiENSMUSG00000018574.
ExpressionAtlasiB1AR28. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB1AR28.
SMRiB1AR28.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 187Acyl-CoA_dh_NInterPro annotationAdd BLAST113
Domaini192 – 294Acyl-CoA_dh_MInterPro annotationAdd BLAST103
Domaini306 – 452Acyl-CoA_dh_1InterPro annotationAdd BLAST147

Sequence similaritiesi

Belongs to the acyl-CoA dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0137. Eukaryota.
COG1960. LUCA.
GeneTreeiENSGT00760000119007.
HOGENOMiHOG000131665.
HOVERGENiHBG050448.

Family and domain databases

Gene3Di1.10.540.10. 1 hit.
InterProiView protein in InterPro
IPR006089. Acyl-CoA_DH_CS.
IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR036250. AcylCo_DH-like_C.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR037069. AcylCoA_DH/ox_N_sf.
IPR009100. AcylCoA_DH/oxidase_NM_dom.
PfamiView protein in Pfam
PF00441. Acyl-CoA_dh_1. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF02771. Acyl-CoA_dh_N. 1 hit.
SUPFAMiSSF47203. SSF47203. 1 hit.
SSF56645. SSF56645. 1 hit.
PROSITEiView protein in PROSITE
PS00072. ACYL_COA_DH_1. 1 hit.
PS00073. ACYL_COA_DH_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B1AR28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSARMTPSV GRQLLRLGAR SSRSTTVLQG QPRPISAQRL YAREATQESK
60 70 80 90 100
SFAVGMFKGQ LTIDQVFPYP SVLSEEQAQF LKELVGPVAR FFEEVNDPAK
110 120 130 140 150
NDALEKVEDD TLQGLKELGA FGLQVPSELG GLGLSNTQYA RLAEIVGMHD
160 170 180 190 200
LGVSVTLGAH QSIGFKGILL YGTKAQREKY LPRVASGQAL AAFCLTEPSS
210 220 230 240 250
GSDVASIRSS AIPSPCGKYY TLNGSKIWIS NGGLADIFTV FAKTPIKDAA
260 270 280 290 300
TGAVKEKITA FVVERSFGGV THGLPEKKMG IKASNTSEVY FDGVKVPSEN
310 320 330 340 350
VLGEVGDGFK VAVNILNNGR FGMAATLAGT MKSLIAKAVD HATNRTQFGD
360 370 380 390 400
KIHNFGVIQE KLARMAILQY VTESMAYMLS ANMDQGFKDF QIEAAISKIF
410 420 430 440 450
CSEAAWKVAD ECIQIMGGMG FMKEPGVERV LRDIRIFRIF EGANDILRLF
460 470 480 490 500
VALQGCMDKG KELTGLGNAL KNPFGNVGLL MGEAGKQLRR RTGIGSGLSL
510 520 530 540 550
SGIVHPELSR SGELAVQALD QFATVVEAKL VKHKKGIVNE QFLLQRLADG
560 570 580 590 600
AIDLYAMVVV LSRASRSLSE GYPTAQHEKM LCDSWCIEAA TRIRENMASL
610 620 630
QSSPQHQELF RNFRSISKAM VENGGLVTGN PLGI
Length:634
Mass (Da):68,551
Last modified:April 8, 2008 - v1
Checksum:i8CA383B0FBFD06D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596185 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000018718; ENSMUSP00000018718; ENSMUSG00000018574.

Similar proteinsi

Entry informationi

Entry nameiB1AR28_MOUSE
AccessioniPrimary (citable) accession number: B1AR28
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 22, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported