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Protein

Kinesin-like protein

Gene

Kif3a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi100 – 107ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Kinesin-like proteinUniRule annotation
Gene namesi
Name:Kif3aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:107689. Kif3a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MicrotubuleUniRule annotation

PTM / Processingi

Proteomic databases

MaxQBiB1AQZ2.
PaxDbiB1AQZ2.
PeptideAtlasiB1AQZ2.
PRIDEiB1AQZ2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000018395.
ExpressionAtlasiB1AQZ2. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB1AQZ2.
SMRiB1AQZ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 345Kinesin motorInterPro annotationAdd BLAST332

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili356 – 380Sequence analysisAdd BLAST25
Coiled coili449 – 504Sequence analysisAdd BLAST56
Coiled coili513 – 564Sequence analysisAdd BLAST52
Coiled coili579 – 610Sequence analysisAdd BLAST32

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0240. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00890000139323.
HOGENOMiHOG000116164.
HOVERGENiHBG052255.
OMAiSGYVVHN.
OrthoDBiEOG091G03RO.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiView protein in InterPro
IPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR036961. Kinesin_motor_dom_sf.
IPR027417. P-loop_NTPase.
PANTHERiPTHR24115. PTHR24115. 1 hit.
PfamiView protein in Pfam
PF00225. Kinesin. 1 hit.
PRINTSiPR00380. KINESINHEAVY.
SMARTiView protein in SMART
SM00129. KISc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B1AQZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPINKSEKPE SCDNVKVVVR CRPLNEREKS MCYRQAVSVD EMRGTITVHK
60 70 80 90 100
TDSSNEPPKT FTFDTVFGPE SKQLDVYNLT ARPIIDSVLE GYNGTIFAYG
110 120 130 140 150
QTGTGKTFTM EGVRAVPGLR GVIPNSFAHI FGHIAKAEGD TRFLVRVSYL
160 170 180 190 200
EIYNEEVRDL LGKDQTQRLE VKERPDVGVY IKDLSAYVVN NADDMDRIMT
210 220 230 240 250
LGHKNRSVGA TNMNEHSSRS HAIFTITIEC SEKGVDGNMH VRMGKLHLVD
260 270 280 290 300
LAGSERQAKT GATGQRLKEA TKINLSLSTL GNVISALVDG KSTHVPYRNS
310 320 330 340 350
KLTRLLQDSL GGNSKTMMCA NIGPADYNYD ETISTLRYAN RAKNIKNKAR
360 370 380 390 400
INEDPKDALL RQFQKEIEEL KKKLEEGEEV SGSDISGSEE DDEEGELGED
410 420 430 440 450
GEKKKKRRGS SSSSSSDSTC SVIEKPLDEF LPHQAGKKKV SPDKMVEMQA
460 470 480 490 500
KIDEERKALE TKLDMEEEER NKARAELERR EKDLLKAQQE HQSLLEKLSA
510 520 530 540 550
LEKKVIVGGV DLLAKAEEQE KLLEESNMEL EERRRRAEQL RKELEEKEQE
560 570 580 590 600
RLDIEEKYTS LQEEAQGKTK KLKKVWTMLM AAKSEMADLQ QEHQREIEGL
610 620 630 640 650
LENIRQLSRE LRLQMLIIDN FIPQDYQEMI ENYVHWNEDI GEWQLKCVAY
660 670 680 690 700
TGNNMRKQTP VPDKKERDPF EVDLSHVYLA YTEESLRQSL MKLERPRTSK
710 720
GKARPKMGRR KRSAKPETVI DSLLQ
Length:725
Mass (Da):82,634
Last modified:April 8, 2008 - v1
Checksum:iE817CB1356DC6AB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596095 Genomic DNA. No translation available.
RefSeqiXP_006532388.1. XM_006532325.3.
UniGeneiMm.88694.

Genome annotation databases

EnsembliENSMUST00000118353; ENSMUSP00000113848; ENSMUSG00000018395.
GeneIDi16568.

Similar proteinsi

Entry informationi

Entry nameiB1AQZ2_MOUSE
AccessioniPrimary (citable) accession number: B1AQZ2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 25, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported