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Protein
Submitted name:

Epoxide hydrolase 1

Gene

EPHX1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Protein family/group databases

ESTHERihuman-EPHX1. Epoxide_hydrolase.

Names & Taxonomyi

Protein namesi
Submitted name:
Epoxide hydrolase 1Imported
Gene namesi
Name:EPHX1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:3401. EPHX1.

PTM / Processingi

Proteomic databases

PaxDbiB1AQP8.
PeptideAtlasiB1AQP8.
PRIDEiB1AQP8.

Expressioni

Gene expression databases

BgeeiENSG00000143819.
ExpressionAtlasiB1AQP8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000272167.

Structurei

3D structure databases

ProteinModelPortaliB1AQP8.
SMRiB1AQP8. Positions 40-134.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 13285EHNInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2565. Eukaryota.
COG0596. LUCA.
GeneTreeiENSGT00390000002210.
HOGENOMiHOG000200026.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR010497. Epoxide_hydro_N.
[Graphical view]
PfamiPF06441. EHN. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Fragment.

B1AQP8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWLEILLTSV LGFAIYWFIS RDKEETLPLE DGWWGPGTRS AAREDDSIRP
60 70 80 90 100
FKVETSDEEI HDLHQRIDKF RFTPPLEDSC FHYGFNSNYL KKVISYWRNE
110 120 130
FDWKKQVEIL NRYPHFKTKI EGLDIHFIHV KPPQLP
Length:136
Mass (Da):16,384
Last modified:April 8, 2008 - v1
Checksum:i29132776B6120DE6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei136 – 1361Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC099066 Genomic DNA. No translation available.
AL591895 Genomic DNA. No translation available.
KF510720 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000448202; ENSP00000408469; ENSG00000143819.
UCSCiuc057pxe.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC099066 Genomic DNA. No translation available.
AL591895 Genomic DNA. No translation available.
KF510720 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliB1AQP8.
SMRiB1AQP8. Positions 40-134.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000272167.

Protein family/group databases

ESTHERihuman-EPHX1. Epoxide_hydrolase.

Proteomic databases

PaxDbiB1AQP8.
PeptideAtlasiB1AQP8.
PRIDEiB1AQP8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000448202; ENSP00000408469; ENSG00000143819.
UCSCiuc057pxe.1. human.

Organism-specific databases

HGNCiHGNC:3401. EPHX1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2565. Eukaryota.
COG0596. LUCA.
GeneTreeiENSGT00390000002210.
HOGENOMiHOG000200026.

Miscellaneous databases

ChiTaRSiEPHX1. human.

Gene expression databases

BgeeiENSG00000143819.
ExpressionAtlasiB1AQP8. baseline and differential.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR010497. Epoxide_hydro_N.
[Graphical view]
PfamiPF06441. EHN. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB1AQP8_HUMAN
AccessioniPrimary (citable) accession number: B1AQP8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 7, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.