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UniProtKB - B1APG3 (B1APG3_HUMAN)

UniProt

B1APG3 - B1APG3_HUMAN

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Protein
Submitted name:

cAMP-dependent protein kinase catalytic subunit beta

Gene

PRKACB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiB1APG3.

Names & Taxonomyi

Protein namesi
Submitted name:
cAMP-dependent protein kinase catalytic subunit betaImported
Gene namesi
Name:PRKACBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:9381. PRKACB.

PTM / Processingi

Proteomic databases

PaxDbiB1APG3.
PeptideAtlasiB1APG3.
PRIDEiB1APG3.

Expressioni

Gene expression databases

BgeeiENSG00000142875.
ExpressionAtlasiB1APG3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000359719.

Structurei

3D structure databases

ProteinModelPortaliB1APG3.
SMRiB1APG3. Positions 22-264.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini50 – 264215Protein kinaseInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0616. Eukaryota.
ENOG410XPQQ. LUCA.
GeneTreeiENSGT00810000125385.
HOGENOMiHOG000233033.
HOVERGENiHBG108317.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1APG3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSARKSSDAS ACSSSEISDS FVKEFLAKAK EDFLKKWENP TQNNAGLEDF 
        60         70         80         90        100
ERKKTLGTGS FGRVMLVKHK ATEQYYAMKI LDKQKVVKLK QIEHTLNEKR 
       110        120        130        140        150
ILQAVNFPFL VRLEYAFKDN SNLYMVMEYV PGGEMFSHLR RIGRFSEPHA 
       160        170        180        190        200
RFYAAQIVLT FEYLHSLDLI YRDLKPENLL IDHQGYIQVT DFGFAKRVKG 
       210        220        230        240        250
RTWTLCGTPE YLAPEIILSK GYNKAVDWWA LGVLIYEMAA GYPPFFADQP 
       260 
IQIYEKIVSG KQNF
Length:264
Mass (Da):30,498
Last modified:April 8, 2008 - v1
Checksum:i181CA0A6367836DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL359504 Genomic DNA. No translation available.
AL450063 Genomic DNA. No translation available.
RefSeqiNP_001287844.1. NM_001300915.1.
UniGeneiHs.487325.

Genome annotation databases

EnsembliENST00000370680; ENSP00000359714; ENSG00000142875.
GeneIDi5567.
UCSCiuc009wcf.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL359504 Genomic DNA. No translation available.
AL450063 Genomic DNA. No translation available.
RefSeqiNP_001287844.1. NM_001300915.1.
UniGeneiHs.487325.

3D structure databases

ProteinModelPortaliB1APG3.
SMRiB1APG3. Positions 22-264.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000359719.

Proteomic databases

PaxDbiB1APG3.
PeptideAtlasiB1APG3.
PRIDEiB1APG3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370680; ENSP00000359714; ENSG00000142875.
GeneIDi5567.
UCSCiuc009wcf.3. human.

Organism-specific databases

CTDi5567.
HGNCiHGNC:9381. PRKACB.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0616. Eukaryota.
ENOG410XPQQ. LUCA.
GeneTreeiENSGT00810000125385.
HOGENOMiHOG000233033.
HOVERGENiHBG108317.

Enzyme and pathway databases

SignaLinkiB1APG3.

Miscellaneous databases

ChiTaRSiPRKACB. human.
GenomeRNAii5567.

Gene expression databases

BgeeiENSG00000142875.
ExpressionAtlasiB1APG3. baseline and differential.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB1APG3_HUMAN
AccessioniPrimary (citable) accession number: B1APG3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 7, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.