UniProtKB - B1APG3 (B1APG3_HUMAN)
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Protein
Submitted name:
cAMP-dependent protein kinase catalytic subunit beta
Gene
PRKACB
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- protein serine/threonine kinase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinaseUniRule annotation, Transferase |
Ligand | ATP-bindingUniRule annotation, Nucleotide-binding |
Enzyme and pathway databases
SignaLinki | B1APG3. |
Names & Taxonomyi
Protein namesi | Submitted name: cAMP-dependent protein kinase catalytic subunit betaImported |
Gene namesi | Name:PRKACBImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000142875.19. |
HGNCi | HGNC:9381. PRKACB. |
Subcellular locationi
Expressioni
Gene expression databases
Bgeei | ENSG00000142875. |
ExpressionAtlasi | B1APG3. baseline and differential. |
Structurei
3D structure databases
ProteinModelPortali | B1APG3. |
SMRi | B1APG3. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 50 – 264 | Protein kinaseInterPro annotationAdd BLAST | 215 |
Sequence similaritiesi
Belongs to the protein kinase superfamily.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0616. Eukaryota. ENOG410XPQQ. LUCA. |
GeneTreei | ENSGT00810000125385. |
HOGENOMi | HOG000233033. |
HOVERGENi | HBG108317. |
Family and domain databases
InterProi | View protein in InterPro IPR011009. Kinase-like_dom_sf. IPR000719. Prot_kinase_dom. IPR017441. Protein_kinase_ATP_BS. IPR008271. Ser/Thr_kinase_AS. |
Pfami | View protein in Pfam PF00069. Pkinase. 1 hit. |
SMARTi | View protein in SMART SM00220. S_TKc. 1 hit. |
SUPFAMi | SSF56112. SSF56112. 1 hit. |
PROSITEi | View protein in PROSITE PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. |
i Sequence
Sequence statusi: Complete.
B1APG3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSARKSSDAS ACSSSEISDS FVKEFLAKAK EDFLKKWENP TQNNAGLEDF
60 70 80 90 100
ERKKTLGTGS FGRVMLVKHK ATEQYYAMKI LDKQKVVKLK QIEHTLNEKR
110 120 130 140 150
ILQAVNFPFL VRLEYAFKDN SNLYMVMEYV PGGEMFSHLR RIGRFSEPHA
160 170 180 190 200
RFYAAQIVLT FEYLHSLDLI YRDLKPENLL IDHQGYIQVT DFGFAKRVKG
210 220 230 240 250
RTWTLCGTPE YLAPEIILSK GYNKAVDWWA LGVLIYEMAA GYPPFFADQP
260
IQIYEKIVSG KQNF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL359504 Genomic DNA. No translation available. AL450063 Genomic DNA. No translation available. |
RefSeqi | NP_001287844.1. NM_001300915.1. |
UniGenei | Hs.487325. |
Genome annotation databases
Ensembli | ENST00000370680; ENSP00000359714; ENSG00000142875. |
GeneIDi | 5567. |
UCSCi | uc009wcf.3. human. |
Similar proteinsi
Entry informationi
Entry namei | B1APG3_HUMAN | |
Accessioni | B1APG3Primary (citable) accession number: B1APG3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 8, 2008 |
Last sequence update: | April 8, 2008 | |
Last modified: | March 28, 2018 | |
This is version 85 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |