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Protein
Submitted name:

cAMP-dependent protein kinase catalytic subunit beta

Gene

PRKACB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiB1APG1

Names & Taxonomyi

Protein namesi
Submitted name:
cAMP-dependent protein kinase catalytic subunit betaImported
Gene namesi
Name:PRKACBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000142875.19
HGNCiHGNC:9381 PRKACB

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000142875

PTM / Processingi

Proteomic databases

MaxQBiB1APG1
PeptideAtlasiB1APG1
PRIDEiB1APG1

Expressioni

Gene expression databases

BgeeiENSG00000142875
ExpressionAtlasiB1APG1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB1APG1
SMRiB1APG1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 197Protein kinaseInterPro annotationAdd BLAST167

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0616 Eukaryota
ENOG410XPQQ LUCA
GeneTreeiENSGT00810000125385
HOGENOMiHOG000233033
HOVERGENiHBG108317

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Fragment.

B1APG1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVKEFLAKA KEDFLKKWEN PTQNNAGLED FERKKTLGTG SFGRVMLVKH
60 70 80 90 100
KATEQYYAMK ILDKQKVVKL KQIEHTLNEK RILQAVNFPF LVRLEYAFKD
110 120 130 140 150
NSNLYMVMEY VPGGEMFSHL RRIGRFSEPH ARFYAAQIVL TFEYLHSLDL
160 170 180 190
IYRDLKPENL LIDHQGYIQV TDFGFAKRVK GRTWTLCGTP EYLAPEI
Length:197
Mass (Da):23,118
Last modified:April 8, 2008 - v1
Checksum:iB77DCA19BB2AD297
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei197Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL359504 Genomic DNA No translation available.
AL450063 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000417530; ENSP00000399326; ENSG00000142875
UCSCiuc001djo.3 human

Similar proteinsi

Entry informationi

Entry nameiB1APG1_HUMAN
AccessioniPrimary (citable) accession number: B1APG1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health