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B1ALS0

- B1ALS0_HUMAN

UniProt

B1ALS0 - B1ALS0_HUMAN

Protein
Submitted name:

cGMP-dependent protein kinase 1

Gene

PRKG1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. cGMP-dependent protein kinase activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cGMP-dependent protein kinase 1Imported
    Gene namesi
    Name:PRKG1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 10

    Organism-specific databases

    HGNCiHGNC:9414. PRKG1.

    PTM / Processingi

    Proteomic databases

    PRIDEiB1ALS0.

    Expressioni

    Gene expression databases

    ArrayExpressiB1ALS0.

    Structurei

    3D structure databases

    ProteinModelPortaliB1ALS0.
    SMRiB1ALS0. Positions 1-181.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di2.60.120.10. 2 hits.
    InterProiIPR002374. cGMP_dep_kinase.
    IPR018490. cNMP-bd-like.
    IPR018488. cNMP-bd_CS.
    IPR000595. cNMP-bd_dom.
    IPR014710. RmlC-like_jellyroll.
    [Graphical view]
    PfamiPF00027. cNMP_binding. 2 hits.
    [Graphical view]
    PRINTSiPR00104. CGMPKINASE.
    SMARTiSM00100. cNMP. 2 hits.
    [Graphical view]
    SUPFAMiSSF51206. SSF51206. 2 hits.
    PROSITEiPS00888. CNMP_BINDING_1. 2 hits.
    PS00889. CNMP_BINDING_2. 1 hit.
    PS50042. CNMP_BINDING_3. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    B1ALS0-1 [UniParc]FASTAAdd to Basket

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    SCIIKEGDVG SLVYVMEDGK VEVTKEGVKL CTMGPGKVFG ELAILYNCTR    50
    TATVKTLVNV KLWAIDRQCF QTIMMRTGLI KHTEYMEFLK SVPTFQSLPE 100
    EILSKLADVL EETHYENGEY IIRQGARGDT FFIISKGTVN VTREDSPSED 150
    PVFLRTLGKG DWFGEKALQG WTWNLFEYVV E 181
    Length:181
    Mass (Da):20,505
    Last modified:April 8, 2008 - v1
    Checksum:i59A0FB824B728689
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC009986 Genomic DNA. No translation available.
    AC022025 Genomic DNA. No translation available.
    AC022537 Genomic DNA. No translation available.
    AC026228 Genomic DNA. No translation available.
    AC027118 Genomic DNA. No translation available.
    AC068062 Genomic DNA. No translation available.
    AC069079 Genomic DNA. No translation available.
    AC073584 Genomic DNA. No translation available.
    AL157399 Genomic DNA. No translation available.
    AL391378 Genomic DNA. No translation available.
    AL596105 Genomic DNA. No translation available.
    AL607031 Genomic DNA. No translation available.
    AL731537 Genomic DNA. No translation available.
    AL928686 Genomic DNA. No translation available.
    KF455236 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000373976; ENSP00000363087; ENSG00000185532.
    UCSCiuc001jjn.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC009986 Genomic DNA. No translation available.
    AC022025 Genomic DNA. No translation available.
    AC022537 Genomic DNA. No translation available.
    AC026228 Genomic DNA. No translation available.
    AC027118 Genomic DNA. No translation available.
    AC068062 Genomic DNA. No translation available.
    AC069079 Genomic DNA. No translation available.
    AC073584 Genomic DNA. No translation available.
    AL157399 Genomic DNA. No translation available.
    AL391378 Genomic DNA. No translation available.
    AL596105 Genomic DNA. No translation available.
    AL607031 Genomic DNA. No translation available.
    AL731537 Genomic DNA. No translation available.
    AL928686 Genomic DNA. No translation available.
    KF455236 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali B1ALS0.
    SMRi B1ALS0. Positions 1-181.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi B1ALS0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000373976 ; ENSP00000363087 ; ENSG00000185532 .
    UCSCi uc001jjn.2. human.

    Organism-specific databases

    HGNCi HGNC:9414. PRKG1.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi PRKG1. human.
    NextBioi 35466696.

    Gene expression databases

    ArrayExpressi B1ALS0.

    Family and domain databases

    Gene3Di 2.60.120.10. 2 hits.
    InterProi IPR002374. cGMP_dep_kinase.
    IPR018490. cNMP-bd-like.
    IPR018488. cNMP-bd_CS.
    IPR000595. cNMP-bd_dom.
    IPR014710. RmlC-like_jellyroll.
    [Graphical view ]
    Pfami PF00027. cNMP_binding. 2 hits.
    [Graphical view ]
    PRINTSi PR00104. CGMPKINASE.
    SMARTi SM00100. cNMP. 2 hits.
    [Graphical view ]
    SUPFAMi SSF51206. SSF51206. 2 hits.
    PROSITEi PS00888. CNMP_BINDING_1. 2 hits.
    PS00889. CNMP_BINDING_2. 1 hit.
    PS50042. CNMP_BINDING_3. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
      , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
      Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (AUG-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiB1ALS0_HUMAN
    AccessioniPrimary (citable) accession number: B1ALS0
    Secondary accession number(s): A6NFM3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3