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Protein
Submitted name:

cGMP-dependent protein kinase 1

Gene

PRKG1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cGMP-dependent protein kinase 1Imported
Gene namesi
Name:PRKG1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:9414. PRKG1.

PTM / Processingi

Proteomic databases

PaxDbiB1ALS0.
PeptideAtlasiB1ALS0.
PRIDEiB1ALS0.

Expressioni

Gene expression databases

BgeeiENSG00000185532.
ExpressionAtlasiB1ALS0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000363092.

Structurei

3D structure databases

ProteinModelPortaliB1ALS0.
SMRiB1ALS0. Positions 1-181.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 9191Cyclic nucleotide-bindingInterPro annotationAdd
BLAST
Domaini94 – 16875Cyclic nucleotide-bindingInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0616. Eukaryota.
ENOG410XPQQ. LUCA.
GeneTreeiENSGT00810000125385.

Family and domain databases

Gene3Di2.60.120.10. 2 hits.
InterProiIPR002374. cGMP_dep_kinase.
IPR018490. cNMP-bd-like.
IPR018488. cNMP-bd_CS.
IPR000595. cNMP-bd_dom.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamiPF00027. cNMP_binding. 2 hits.
[Graphical view]
PRINTSiPR00104. CGMPKINASE.
SMARTiSM00100. cNMP. 2 hits.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 2 hits.
PROSITEiPS00888. CNMP_BINDING_1. 2 hits.
PS00889. CNMP_BINDING_2. 1 hit.
PS50042. CNMP_BINDING_3. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B1ALS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SCIIKEGDVG SLVYVMEDGK VEVTKEGVKL CTMGPGKVFG ELAILYNCTR
60 70 80 90 100
TATVKTLVNV KLWAIDRQCF QTIMMRTGLI KHTEYMEFLK SVPTFQSLPE
110 120 130 140 150
EILSKLADVL EETHYENGEY IIRQGARGDT FFIISKGTVN VTREDSPSED
160 170 180
PVFLRTLGKG DWFGEKALQG WTWNLFEYVV E
Length:181
Mass (Da):20,505
Last modified:April 8, 2008 - v1
Checksum:i59A0FB824B728689
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022537 Genomic DNA. No translation available.
AC068062 Genomic DNA. No translation available.
AC069079 Genomic DNA. No translation available.
AC073584 Genomic DNA. No translation available.
AL157399 Genomic DNA. No translation available.
AL596105 Genomic DNA. No translation available.
AL607031 Genomic DNA. No translation available.
AL731537 Genomic DNA. No translation available.
KF455236 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000373976; ENSP00000363087; ENSG00000185532.
UCSCiuc057thb.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022537 Genomic DNA. No translation available.
AC068062 Genomic DNA. No translation available.
AC069079 Genomic DNA. No translation available.
AC073584 Genomic DNA. No translation available.
AL157399 Genomic DNA. No translation available.
AL596105 Genomic DNA. No translation available.
AL607031 Genomic DNA. No translation available.
AL731537 Genomic DNA. No translation available.
KF455236 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliB1ALS0.
SMRiB1ALS0. Positions 1-181.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000363092.

Proteomic databases

PaxDbiB1ALS0.
PeptideAtlasiB1ALS0.
PRIDEiB1ALS0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000373976; ENSP00000363087; ENSG00000185532.
UCSCiuc057thb.1. human.

Organism-specific databases

HGNCiHGNC:9414. PRKG1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0616. Eukaryota.
ENOG410XPQQ. LUCA.
GeneTreeiENSGT00810000125385.

Miscellaneous databases

ChiTaRSiPRKG1. human.

Gene expression databases

BgeeiENSG00000185532.
ExpressionAtlasiB1ALS0. baseline and differential.

Family and domain databases

Gene3Di2.60.120.10. 2 hits.
InterProiIPR002374. cGMP_dep_kinase.
IPR018490. cNMP-bd-like.
IPR018488. cNMP-bd_CS.
IPR000595. cNMP-bd_dom.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamiPF00027. cNMP_binding. 2 hits.
[Graphical view]
PRINTSiPR00104. CGMPKINASE.
SMARTiSM00100. cNMP. 2 hits.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 2 hits.
PROSITEiPS00888. CNMP_BINDING_1. 2 hits.
PS00889. CNMP_BINDING_2. 1 hit.
PS50042. CNMP_BINDING_3. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB1ALS0_HUMAN
AccessioniPrimary (citable) accession number: B1ALS0
Secondary accession number(s): A6NFM3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 7, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.