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Protein
Submitted name:

Probable global transcription activator SNF2L2

Gene

SMARCA2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Probable global transcription activator SNF2L2Imported
Gene namesi
Name:SMARCA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:11098. SMARCA2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000080503.

PTM / Processingi

Proteomic databases

MaxQBiB1ALG2.
PaxDbiB1ALG2.
PeptideAtlasiB1ALG2.
PRIDEiB1ALG2.

Expressioni

Gene expression databases

BgeeiENSG00000080503.
ExpressionAtlasiB1ALG2. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000265773.

Structurei

3D structure databases

ProteinModelPortaliB1ALG2.
SMRiB1ALG2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini83 – 153BromoInterPro annotationAdd BLAST71

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili163 – 193Sequence analysisAdd BLAST31

Keywords - Domaini

BromodomainSAAS annotation, Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0386. Eukaryota.
COG0553. LUCA.
COG5076. LUCA.
GeneTreeiENSGT00550000074659.
HOGENOMiHOG000049057.
HOVERGENiHBG062263.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
InterProiIPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR030088. SMARCA2.
[Graphical view]
PANTHERiPTHR10799:SF541. PTHR10799:SF541. 2 hits.
PfamiPF00439. Bromodomain. 1 hit.
[Graphical view]
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1ALG2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEEVRLKKR KRRRNVDKDP AKEDVEKAKK RRGRPPAEKL SPNPPKLTKQ
60 70 80 90 100
MNAIIDTVIN YKDRCNVEKV PSNSQLEIEG NSSGRQLSEV FIQLPSRKEL
110 120 130 140 150
PEYYELIRKP VDFKKIKERI RNHKYRSLGD LEKDVMLLCH NAQTFNLEGS
160 170 180 190 200
QIYEDSIVLQ SVFKSARQKI AKEEESEDES NEEEEEEDEE ESESEAKSVK
210 220 230 240 250
VKIKLNKKDD KGRDKGKGKK RPNRGKAKPV VSDFDSDEEQ DEREQSEGSG

TDDE
Length:254
Mass (Da):29,492
Last modified:April 8, 2008 - v1
Checksum:i39FC1491B844E2DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138755 Genomic DNA. No translation available.
AL359076 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000382186; ENSP00000371621; ENSG00000080503.
ENST00000634931; ENSP00000489433; ENSG00000080503.
UCSCiuc064rwi.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138755 Genomic DNA. No translation available.
AL359076 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliB1ALG2.
SMRiB1ALG2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000265773.

Proteomic databases

MaxQBiB1ALG2.
PaxDbiB1ALG2.
PeptideAtlasiB1ALG2.
PRIDEiB1ALG2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000382186; ENSP00000371621; ENSG00000080503.
ENST00000634931; ENSP00000489433; ENSG00000080503.
UCSCiuc064rwi.1. human.

Organism-specific databases

HGNCiHGNC:11098. SMARCA2.
OpenTargetsiENSG00000080503.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0386. Eukaryota.
COG0553. LUCA.
COG5076. LUCA.
GeneTreeiENSGT00550000074659.
HOGENOMiHOG000049057.
HOVERGENiHBG062263.

Miscellaneous databases

ChiTaRSiSMARCA2. human.

Gene expression databases

BgeeiENSG00000080503.
ExpressionAtlasiB1ALG2. baseline and differential.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
InterProiIPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR030088. SMARCA2.
[Graphical view]
PANTHERiPTHR10799:SF541. PTHR10799:SF541. 2 hits.
PfamiPF00439. Bromodomain. 1 hit.
[Graphical view]
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB1ALG2_HUMAN
AccessioniPrimary (citable) accession number: B1ALG2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 30, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.