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Protein

Kinesin-like protein

Gene

KIF12

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Motor proteinUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Kinesin-like proteinUniRule annotation
Gene namesi
Name:KIF12Imported
ORF Names:hCG_32518Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:21495. KIF12.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

MicrotubuleUniRule annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134931618.

PTM / Processingi

Proteomic databases

PeptideAtlasiB1ALC3.

Expressioni

Gene expression databases

BgeeiENSG00000136883.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000363232.

Structurei

3D structure databases

SMRiB1ALC3. Positions 21-260.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 227227Kinesin motorInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili289 – 33042Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.UniRule annotationSAAS annotation
Contains 1 kinesin motor domain.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4280. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00810000125470.
HOGENOMiHOG000049053.
HOVERGENiHBG052248.
KOiK10399.
OMAiPLAHWAC.
OrthoDBiEOG091G0SNP.
TreeFamiTF324584.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR028763. Kif12.
IPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 1 hit.
PTHR24115:SF418. PTHR24115:SF418. 1 hit.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1ALC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQRTFAWLLD RVQHLGAPVT LRASYLEIYN EQVRDLLSLG SPRPLPVRWN
60 70 80 90 100
KTRGFYVEQL RVVEFGSLEA LMELLQTGLS RRRNSAHTLN QASSRSHALL
110 120 130 140 150
TLYISRQTAQ QMPSVDPGEP PVGGKLCFVD LAGSEKVAAT GSRGELMLEA
160 170 180 190 200
NSINRSLLAL GHCISLLLDP QRKQSHIPFR DSKLTKLLAD SLGGRGVTLM
210 220 230 240 250
VACVSPSAQC LPETLSTLRY ASRAQRVTTR PQAPKSPVAK QPQRLETEML
260 270 280 290 300
QLQEENRRLQ FQLDQMDCKA SGLSGARVAW AQRNLYGMLQ EFMLENERLR
310 320 330 340 350
KEKSQLQNSR DLAQNEQRIL AQQVHALERR LLSACYHHQQ GPGLTPPCPC
360 370 380 390 400
LMAPAPPCHA LPPLYSCPCC HICPLCRVPL AHWACLPGEH HLPQVLDPEA
410 420 430 440 450
SGGRPPSARP PPWAPPCSPG SAKCPRERSH SDWTQTRVLA EMLTEEEVVP
460 470 480 490 500
SAPPLPVRPP KTSPGLRGGA GVPNLAQRLE ALRDQIGSSL RRGRSQPPCS
510
EGARSPGQVL PPH
Length:513
Mass (Da):56,627
Last modified:April 8, 2008 - v1
Checksum:i696DB753C0966563
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137850 Genomic DNA. No translation available.
CH471090 Genomic DNA. Translation: EAW87407.1.
RefSeqiNP_612433.1. NM_138424.1.
UniGeneiHs.28149.

Genome annotation databases

EnsembliENST00000374118; ENSP00000363232; ENSG00000136883.
GeneIDi113220.
KEGGihsa:113220.
UCSCiuc004bif.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137850 Genomic DNA. No translation available.
CH471090 Genomic DNA. Translation: EAW87407.1.
RefSeqiNP_612433.1. NM_138424.1.
UniGeneiHs.28149.

3D structure databases

SMRiB1ALC3. Positions 21-260.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000363232.

Proteomic databases

PeptideAtlasiB1ALC3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000374118; ENSP00000363232; ENSG00000136883.
GeneIDi113220.
KEGGihsa:113220.
UCSCiuc004bif.3. human.

Organism-specific databases

CTDi113220.
HGNCiHGNC:21495. KIF12.
PharmGKBiPA134931618.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4280. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00810000125470.
HOGENOMiHOG000049053.
HOVERGENiHBG052248.
KOiK10399.
OMAiPLAHWAC.
OrthoDBiEOG091G0SNP.
TreeFamiTF324584.

Miscellaneous databases

GenomeRNAii113220.

Gene expression databases

BgeeiENSG00000136883.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR028763. Kif12.
IPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 1 hit.
PTHR24115:SF418. PTHR24115:SF418. 1 hit.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB1ALC3_HUMAN
AccessioniPrimary (citable) accession number: B1ALC3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 7, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.