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Protein

NUT family member 2E

Gene

NUTM2E

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
NUT family member 2E
Gene namesi
Name:NUTM2E
Synonyms:FAM22E
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:23448. NUTM2E.

Pathology & Biotechi

Organism-specific databases

DisGeNETi283008.
MalaCardsiNUTM2E.
OpenTargetsiENSG00000228570.
PharmGKBiPA134988973.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003379941 – 878NUT family member 2EAdd BLAST878

Proteomic databases

PaxDbiB1AL46.
PRIDEiB1AL46.

Expressioni

Gene expression databases

BgeeiENSG00000228570.
CleanExiHS_FAM22E.
ExpressionAtlasiB1AL46. baseline and differential.
GenevisibleiB1AL46. HS.

Organism-specific databases

HPAiHPA064635.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000407521.

Structurei

3D structure databases

ProteinModelPortaliB1AL46.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi278 – 285Poly-Pro8
Compositional biasi425 – 514Pro-richAdd BLAST90
Compositional biasi754 – 757Poly-Glu4

Sequence similaritiesi

Belongs to the NUT family.Curated

Phylogenomic databases

eggNOGiENOG410J94Q. Eukaryota.
ENOG4111C0H. LUCA.
GeneTreeiENSGT00410000025793.
HOGENOMiHOG000112470.
HOVERGENiHBG107898.
InParanoidiB1AL46.
OMAiRIAMREW.
OrthoDBiEOG091G034P.
PhylomeDBiB1AL46.
TreeFamiTF337728.

Family and domain databases

InterProiView protein in InterPro
IPR024310. NUT.
IPR024309. NUT_N.
PANTHERiPTHR22879. PTHR22879. 1 hit.
PfamiView protein in Pfam
PF12881. NUT. 1 hit.

Sequencei

Sequence statusi: Complete.

B1AL46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVKGPSGRS FCCESEGQFK SCLKRHTPSL LLPSSWKGNS GSCLMAEALH
60 70 80 90 100
RTSPTPNSCP LPLPLCRMSG VLCSRNLFTF KFSLFQLDSG ASGEPGHSLG
110 120 130 140 150
LTLGFSYCGN CQTAVVSAQP EGMASNGAYP VLGPGVTANP GTSLSVFTAL
160 170 180 190 200
PFTTPAPGPA HGPLLVTAGA PPGGPLVLST FPSTPLVTEQ DGCSPSGAGA
210 220 230 240 250
SNVFVQMRTE VGPVKAAQAQ TLVLTQAPLV WQAPGALCGG VVCPPPLLLA
260 270 280 290 300
AAPVVPVMAA QVVGGTQACE GGWSQGLPLP PPPPPAAQLP PIVSQGNAGP
310 320 330 340 350
WPQGAHGESS LASSQAKAPP DDSCNPRSVY ENFRLWQHYK PLARRHLPQS
360 370 380 390 400
PDTEALSCFL IPVLRSLARR KPTMTLEEGL WRAMREWQHT SNFDRMIFYE
410 420 430 440 450
MAEKFLEFEA EEEMQIQKSQ WMKGPQCLPP PATPRLEPRG PPAPEVVKQP
460 470 480 490 500
VYLPSKAGPK AQTACLPPPR PQRPVTKARR PPPQPHRRAE TKARLPPPRP
510 520 530 540 550
QRPAETKVPE EIPPEVVQEY VDIMEELLGP SLGATGEPEK QREEGKVKQP
560 570 580 590 600
QEEDWTPPDP GLLSYIDKLC SQKDFVTKVE AVIHPQFLEE LLSPDPQMDF
610 620 630 640 650
LALSQDLEQE EGLTLAQLVE KRLPPLKEKQ HSRAAPSRGT ARLDSSSSKF
660 670 680 690 700
AAGQGAERDV PDPQEGVGME TCPPQTTARD SQGRGRAHTG MARSEDSVVL
710 720 730 740 750
LGCQDSPGLR AARPTSPPQD HRPTCPGVGT KDALDLPGGS PVRESHGLAQ
760 770 780 790 800
GSSEEEELPS LAFLLGSQHK LLPWWLPQSP VPASGLLSPE KWGPQGTHQS
810 820 830 840 850
PSAERRGLNL APSPANKAKK QPLFGSLSPA EKTPHRGPGL RVSGEQSLTW
860 870
GLGGPSQSQK RKGDPLVSRK EKKQHCSQ
Length:878
Mass (Da):93,979
Last modified:April 20, 2010 - v3
Checksum:iC5AE853FD6E57202
GO

Sequence cautioni

The sequence CAC78758 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL135925 Genomic DNA. Translation: CAC78758.2. Sequence problems.

Genome annotation databases

EnsembliENST00000429984; ENSP00000407521; ENSG00000228570.
UCSCiuc057umg.1. human.

Similar proteinsi

Entry informationi

Entry nameiNTM2E_HUMAN
AccessioniPrimary (citable) accession number: B1AL46
Secondary accession number(s): A6NHL0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: April 20, 2010
Last modified: August 30, 2017
This is version 69 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families