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Protein
Submitted name:

Serine/threonine-protein kinase mTOR

Gene

MTOR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinasePROSITE-ProRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase mTORImported
Gene namesi
Name:MTORImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000198793.12.
HGNCiHGNC:3942. MTOR.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198793.

PTM / Processingi

Proteomic databases

MaxQBiB1AKQ2.
PaxDbiB1AKQ2.
PeptideAtlasiB1AKQ2.
PRIDEiB1AKQ2.

Expressioni

Gene expression databases

BgeeiENSG00000198793.
ExpressionAtlasiB1AKQ2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB1AKQ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 80PI3K/PI4KInterPro annotationAdd BLAST80

Sequence similaritiesi

Belongs to the PI3/PI4-kinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0891. Eukaryota.
COG5032. LUCA.
GeneTreeiENSGT00890000139466.
HOVERGENiHBG083885.

Family and domain databases

Gene3Di1.10.1070.11. 1 hit.
InterProiView protein in InterPro
IPR011009. Kinase-like_dom.
IPR000403. PI3/4_kinase_cat_dom.
IPR036940. PI3/4_kinase_cat_sf.
IPR026683. TOR.
PANTHERiPTHR11139:SF9. PTHR11139:SF9. 1 hit.
PfamiView protein in Pfam
PF00454. PI3_PI4_kinase. 1 hit.
SMARTiView protein in SMART
SM00146. PI3Kc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50290. PI3_4_KINASE_3. 1 hit.

Sequencei

Sequence statusi: Fragment.

B1AKQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDRLSGKIL HIDFGDCFEV AMTREKFPEK IPFRLTRMLT NAMEVTGLDG
60 70 80 90 100
NYRITCHTVM EVLREHKDSV MAVLEAFVYD PLLNWRLMDT NTKGNKRSRT
110 120 130 140 150
RTDSYSAGQS VEILDGVELG EPAHKKTGTT VPESIHSFIG DGLVKPEALN
160
KKAIQIINRV R
Length:161
Mass (Da):18,235
Last modified:April 8, 2008 - v1
Checksum:i4422F10A66FBA916
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei161Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049653 Genomic DNA. No translation available.
AL109811 Genomic DNA. No translation available.
AL391561 Genomic DNA. No translation available.
KF495866 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000455339; ENSP00000398745; ENSG00000198793.
UCSCiuc057cfw.1. human.

Similar proteinsi

Entry informationi

Entry nameiB1AKQ2_HUMAN
AccessioniPrimary (citable) accession number: B1AKQ2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 25, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported