SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B1AKC3

- B1AKC3_HUMAN

UniProt

B1AKC3 - B1AKC3_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: E3 ubiquitin-protein ligase parkin
Gene
PARK2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. ubiquitin-protein transferase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    E3 ubiquitin-protein ligase parkinImported
    Gene namesi
    Name:PARK2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 6

    Organism-specific databases

    HGNCiHGNC:8607. PARK2.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: InterPro
    2. mitochondrion Source: InterPro
    Complete GO annotation...

    Expressioni

    Gene expression databases

    ArrayExpressiB1AKC3.

    Structurei

    3D structure databases

    ProteinModelPortaliB1AKC3.
    SMRiB1AKC3. Positions 1-76, 142-353.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000013184.
    HOVERGENiHBG053682.

    Family and domain databases

    InterProiIPR003977. Parkin.
    IPR000626. Ubiquitin-like.
    IPR029071. Ubiquitin-rel_dom.
    [Graphical view]
    PfamiPF00240. ubiquitin. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037880. Parkin. 1 hit.
    PRINTSiPR01475. PARKIN.
    SMARTiSM00213. UBQ. 1 hit.
    [Graphical view]
    SUPFAMiSSF54236. SSF54236. 1 hit.
    PROSITEiPS50053. UBIQUITIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1AKC3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIVFVRFNSS HGFPVEVDSD TSIFQLKEVV AKRQGVPADQ LRVIFAGKEL    50
    RNDWTVQNCD LDQQSIVHIV QRPWRKGQEM NATGGDDPRN AAGGCEREPQ 100
    SLTRVDLSSS VLPGDSVGLA VILHTDSRKD SPPAGSPAGR SIYNSFYVYC 150
    KGPCQRVQPG KLRVQCSTCR QATLTLTQGP SCWDDVLIPN RMSGECQSPH 200
    CPGTSAEFFF KCGAHPTSDK ETSVALHLIA TNSRNITCIT CTDVRSPVLV 250
    FQCNSRHVIC LDCFHLYCVT RLNDRQFVHD PQLGYSLPCV AGCPNSLIKE 300
    LHHFRILGEE QYNRYQQYGA EECVLQMGGV LCPRPGCGAG LLPEPDQRKV 350
    TCEGGNGLGC GYGQRRTK 368
    Length:368
    Mass (Da):40,537
    Last modified:April 8, 2008 - v1
    Checksum:i6DC21E6D4C5D8538
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL008631 Genomic DNA. No translation available.
    AL035697 Genomic DNA. No translation available.
    AL078583 Genomic DNA. No translation available.
    AL132982 Genomic DNA. No translation available.
    AL138716 Genomic DNA. No translation available.
    AL445215 Genomic DNA. No translation available.
    AP000886 Genomic DNA. No translation available.
    AP000887 Genomic DNA. No translation available.
    AP000888 Genomic DNA. No translation available.
    AP001576 Genomic DNA. No translation available.
    AP001577 Genomic DNA. No translation available.
    AP001578 Genomic DNA. No translation available.
    AP002091 Genomic DNA. No translation available.
    AP003699 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000366892; ENSP00000355858; ENSG00000185345.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL008631 Genomic DNA. No translation available.
    AL035697 Genomic DNA. No translation available.
    AL078583 Genomic DNA. No translation available.
    AL132982 Genomic DNA. No translation available.
    AL138716 Genomic DNA. No translation available.
    AL445215 Genomic DNA. No translation available.
    AP000886 Genomic DNA. No translation available.
    AP000887 Genomic DNA. No translation available.
    AP000888 Genomic DNA. No translation available.
    AP001576 Genomic DNA. No translation available.
    AP001577 Genomic DNA. No translation available.
    AP001578 Genomic DNA. No translation available.
    AP002091 Genomic DNA. No translation available.
    AP003699 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali B1AKC3.
    SMRi B1AKC3. Positions 1-76, 142-353.
    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000366892 ; ENSP00000355858 ; ENSG00000185345 .

    Organism-specific databases

    HGNCi HGNC:8607. PARK2.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000013184.
    HOVERGENi HBG053682.

    Miscellaneous databases

    NextBioi 35466533.

    Gene expression databases

    ArrayExpressi B1AKC3.

    Family and domain databases

    InterProi IPR003977. Parkin.
    IPR000626. Ubiquitin-like.
    IPR029071. Ubiquitin-rel_dom.
    [Graphical view ]
    Pfami PF00240. ubiquitin. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037880. Parkin. 1 hit.
    PRINTSi PR01475. PARKIN.
    SMARTi SM00213. UBQ. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54236. SSF54236. 1 hit.
    PROSITEi PS50053. UBIQUITIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
      , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
      Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiB1AKC3_HUMAN
    AccessioniPrimary (citable) accession number: B1AKC3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: September 3, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

    Similar proteinsi