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B1AK73

- B1AK73_HUMAN

UniProt

B1AK73 - B1AK73_HUMAN

Protein
Submitted name:

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Gene

PLCB1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. phosphatidylinositol phospholipase C activity Source: InterPro

    GO - Biological processi

    1. brain development Source: InterPro
    2. intracellular signal transduction Source: InterPro
    3. regulation of cell cycle Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1Imported
    Gene namesi
    Name:PLCB1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 20

    Organism-specific databases

    HGNCiHGNC:15917. PLCB1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro
    2. nucleus Source: InterPro

    Expressioni

    Gene expression databases

    ArrayExpressiB1AK73.

    Structurei

    3D structure databases

    ProteinModelPortaliB1AK73.
    SMRiB1AK73. Positions 11-205.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000200010.
    HOVERGENiHBG075740.
    OMAiQNKMLEP.

    Family and domain databases

    Gene3Di2.30.29.30. 1 hit.
    InterProiIPR011993. PH_like_dom.
    IPR001192. PI-PLC_fam.
    IPR028400. PLC-beta1.
    [Graphical view]
    PANTHERiPTHR10336. PTHR10336. 1 hit.
    PTHR10336:SF12. PTHR10336:SF12. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    B1AK73-1 [UniParc]FASTAAdd to Basket

    « Hide

    AGAQPGVHAL QLKPVCVSDS LKKGTKFVKW DDDSTIVTPI ILRTDPQGFF    50
    FYWTDQNKET ELLDLSLVKD ARCGRHAKAP KDPKLRELLD VGNIGRLEQR 100
    MITVVYGPDL VNISHLNLVA FQEEVAKEWT NEVFSLATNL LAQNMSRDAF 150
    LEKAYTKLKL QVTPEGRIPL KNIYRLFSAD RKRVETALEA CSLPSSRVEK 200
    ANEAAKSEQS CGKAPPKHFH LHFIKQNKML EP 232
    Length:232
    Mass (Da):26,197
    Last modified:April 8, 2008 - v1
    Checksum:i14337144027AEFD9
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei232 – 2321Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL021406 Genomic DNA. No translation available.
    AL031655 Genomic DNA. No translation available.
    AL031683 Genomic DNA. No translation available.
    AL034551 Genomic DNA. No translation available.
    AL049593 Genomic DNA. No translation available.
    AL049632 Genomic DNA. No translation available.
    AL050315 Genomic DNA. No translation available.
    AL050319 Genomic DNA. No translation available.
    AL050323 Genomic DNA. No translation available.
    AL121589 Genomic DNA. No translation available.
    AL365212 Genomic DNA. No translation available.
    AL445567 Genomic DNA. No translation available.
    KF456806 Genomic DNA. No translation available.
    KF456807 Genomic DNA. No translation available.
    KF456810 Genomic DNA. No translation available.
    KF456814 Genomic DNA. No translation available.
    KF456816 Genomic DNA. No translation available.
    KF510482 Genomic DNA. No translation available.
    KF511324 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000404098; ENSP00000384001; ENSG00000182621.
    UCSCiuc002wmz.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL021406 Genomic DNA. No translation available.
    AL031655 Genomic DNA. No translation available.
    AL031683 Genomic DNA. No translation available.
    AL034551 Genomic DNA. No translation available.
    AL049593 Genomic DNA. No translation available.
    AL049632 Genomic DNA. No translation available.
    AL050315 Genomic DNA. No translation available.
    AL050319 Genomic DNA. No translation available.
    AL050323 Genomic DNA. No translation available.
    AL121589 Genomic DNA. No translation available.
    AL365212 Genomic DNA. No translation available.
    AL445567 Genomic DNA. No translation available.
    KF456806 Genomic DNA. No translation available.
    KF456807 Genomic DNA. No translation available.
    KF456810 Genomic DNA. No translation available.
    KF456814 Genomic DNA. No translation available.
    KF456816 Genomic DNA. No translation available.
    KF510482 Genomic DNA. No translation available.
    KF511324 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali B1AK73.
    SMRi B1AK73. Positions 11-205.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000404098 ; ENSP00000384001 ; ENSG00000182621 .
    UCSCi uc002wmz.2. human.

    Organism-specific databases

    HGNCi HGNC:15917. PLCB1.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000200010.
    HOVERGENi HBG075740.
    OMAi QNKMLEP.

    Miscellaneous databases

    ChiTaRSi PLCB1. human.
    NextBioi 35466511.

    Gene expression databases

    ArrayExpressi B1AK73.

    Family and domain databases

    Gene3Di 2.30.29.30. 1 hit.
    InterProi IPR011993. PH_like_dom.
    IPR001192. PI-PLC_fam.
    IPR028400. PLC-beta1.
    [Graphical view ]
    PANTHERi PTHR10336. PTHR10336. 1 hit.
    PTHR10336:SF12. PTHR10336:SF12. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
      , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
      Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiB1AK73_HUMAN
    AccessioniPrimary (citable) accession number: B1AK73
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3