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Protein
Submitted name:

Astrotactin-1

Gene

ASTN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Astrotactin-1Imported
Gene namesi
Name:ASTN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:773. ASTN1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei151 – 17525HelicalSequence analysisAdd
BLAST
Transmembranei386 – 40419HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 12281207Sequence analysisPRO_5002759907Add
BLAST

Proteomic databases

PaxDbiB1AJS1.
PRIDEiB1AJS1.

Expressioni

Gene expression databases

BgeeiB1AJS1.
ExpressionAtlasiB1AJS1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000354536.

Structurei

3D structure databases

ProteinModelPortaliB1AJS1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini462 – 49938EGF-likeInterPro annotationAdd
BLAST
Domaini603 – 64442EGF-likeInterPro annotationAdd
BLAST
Domaini651 – 70050EGF-likeInterPro annotationAdd
BLAST
Domaini803 – 991189MACPFInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHIU. Eukaryota.
ENOG4110VB2. LUCA.
GeneTreeiENSGT00390000003140.
HOGENOMiHOG000034112.
HOVERGENiHBG050597.
OrthoDBiEOG7BZVRG.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR026995. Astrotactin.
IPR000742. EGF-like_dom.
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
IPR020864. MACPF.
[Graphical view]
PANTHERiPTHR16592. PTHR16592. 1 hit.
SMARTiSM00181. EGF. 3 hits.
SM00457. MACPF. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 2 hits.

Sequencei

Sequence statusi: Complete.

B1AJS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALAGLCALL ACCWGPAAVL ATAAGDVDPS KELECKLKSI TVSALPFLRE
60 70 80 90 100
NDLSIMHSPS ASEPKLLFSV RNDFPGEMVV VDDLENTELP YFVLEISGNT
110 120 130 140 150
EDIPLVRWRQ QWLENGTLLF HIHHQDGAPS LPGQDPTEEP QHESAEEELR
160 170 180 190 200
ILHISVMGGM IALLLSILCL VMILYTRRRW CKRRRVPQPQ KSASAEAANE
210 220 230 240 250
IHYIPSVLIG GHGRESLRNA RVQGHNSSGT LSIRETPILD GYEYDITDLR
260 270 280 290 300
HHLQRECMNG GEDFASQVTR TLDSLQGCNE KSGMDLTPGS DNAKLSLMNK
310 320 330 340 350
YKDNIIATSP VDSNHQQATL LSHTSSSQRK RINNKARAGS AFLNPEGDSG
360 370 380 390 400
TEAENDPQLT FYTDPSRSRR RSRVGSPRSP VNKTTLTLIS ITSCVIGLVC
410 420 430 440 450
SSHVNCPLVV KITLHVPEHL IADGSRFILL EGSQLDASDW LNPAQVVLFS
460 470 480 490 500
QQNSSGPWAM DLCARRLLDP CEHQCDPETG ECLCYEGYMK DPVHKHLCIR
510 520 530 540 550
NEWGTNQGPW PYTIFQRGFD LVLGEQPSDK IFRFTYTLGE GMWLPLSKSF
560 570 580 590 600
VIPPAELAIN PSAKCKTDMT VMEDAVEVRE ELMTSSSFDS LEVLLDSFGP
610 620 630 640 650
VRDCSKDNGG CSKNFRCISD RKLDSTGCVC PSGLSPMKDS SGCYDRHIGV
660 670 680 690 700
DCSDGFNGGC EQLCLQQMAP FPDDPTLYNI LMFCGCIEDY KLGVDGRSCQ
710 720 730 740 750
LITETCPEGS DCGESRELPM NQTLFGEMFF GYNNHSKEVA AGQVLKGTFR
760 770 780 790 800
QNNFARGLDQ QLPDGLVVAT VPLENQCLEE ISEPTPDPDF LTGMVNFSEV
810 820 830 840 850
SGYPVLQHWK VRSVMYHIKL NQVAISQALS NALHSLDGAT SRADFVALLD
860 870 880 890 900
QFGNHYIQEA IYGFEESCSI WYPNKQVQRR LWLEYEDISK GNSPSDESEE
910 920 930 940 950
RERDPKVLTF PEYITSLSDS GTKHMAAGVR MECHSKGRCP SSCPLCHVTS
960 970 980 990 1000
SPDTPAEPVL LEVTKAAPIY ELVTNNQTQR LLQEATMSSL WCSGTGDVIE
1010 1020 1030 1040 1050
DWCRCDSTAF GADGLPTCAP LPQPVLRLST VHEPSSTLVV LEWEHSEPPI
1060 1070 1080 1090 1100
GVQIVDYLLR QEKVTDRMDH SKVETETVLS FVDDIISGAK SPCAMPSQVP
1110 1120 1130 1140 1150
DKQLTTISLI IRCLEPDTIY MFTLWGVDNT GRRSRPSDVI VKTPCPVVDD
1160 1170 1180 1190 1200
VKAQEIADKI YNLFNGYTSG KEQQTAYNTL LDLGSPTLHR VLYHYNQHYE
1210 1220
SFGEFTWRCE DELGPRLPAC WDSQRSCR
Length:1,228
Mass (Da):136,486
Last modified:April 8, 2008 - v1
Checksum:iAC672AE9B387D2D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021398 Genomic DNA. No translation available.
AL022145 Genomic DNA. No translation available.
AL031290 Genomic DNA. No translation available.
AL136983 Genomic DNA. No translation available.
KF454939 Genomic DNA. No translation available.
KF455086 Genomic DNA. No translation available.
RefSeqiNP_001273093.1. NM_001286164.1.
UniGeneiHs.495897.

Genome annotation databases

EnsembliENST00000367657; ENSP00000356629; ENSG00000152092.
GeneIDi460.
UCSCiuc001glb.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021398 Genomic DNA. No translation available.
AL022145 Genomic DNA. No translation available.
AL031290 Genomic DNA. No translation available.
AL136983 Genomic DNA. No translation available.
KF454939 Genomic DNA. No translation available.
KF455086 Genomic DNA. No translation available.
RefSeqiNP_001273093.1. NM_001286164.1.
UniGeneiHs.495897.

3D structure databases

ProteinModelPortaliB1AJS1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000354536.

Proteomic databases

PaxDbiB1AJS1.
PRIDEiB1AJS1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367657; ENSP00000356629; ENSG00000152092.
GeneIDi460.
UCSCiuc001glb.3. human.

Organism-specific databases

CTDi460.
HGNCiHGNC:773. ASTN1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IHIU. Eukaryota.
ENOG4110VB2. LUCA.
GeneTreeiENSGT00390000003140.
HOGENOMiHOG000034112.
HOVERGENiHBG050597.
OrthoDBiEOG7BZVRG.

Miscellaneous databases

ChiTaRSiASTN1. human.
GenomeRNAii460.

Gene expression databases

BgeeiB1AJS1.
ExpressionAtlasiB1AJS1. baseline and differential.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR026995. Astrotactin.
IPR000742. EGF-like_dom.
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
IPR020864. MACPF.
[Graphical view]
PANTHERiPTHR16592. PTHR16592. 1 hit.
SMARTiSM00181. EGF. 3 hits.
SM00457. MACPF. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiB1AJS1_HUMAN
AccessioniPrimary (citable) accession number: B1AJS1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: June 8, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.