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Protein
Submitted name:

Astrotactin-1

Gene

ASTN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Astrotactin-1Imported
Gene namesi
Name:ASTN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000152092.15
HGNCiHGNC:773 ASTN1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei151 – 175HelicalSequence analysisAdd BLAST25
Transmembranei386 – 404HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000152092

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500275990722 – 1228Sequence analysisAdd BLAST1207

Proteomic databases

PeptideAtlasiB1AJS1
PRIDEiB1AJS1

Expressioni

Gene expression databases

BgeeiENSG00000152092
ExpressionAtlasiB1AJS1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB1AJS1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini462 – 499EGF-likeInterPro annotationAdd BLAST38
Domaini603 – 644EGF-likeInterPro annotationAdd BLAST42
Domaini651 – 700EGF-likeInterPro annotationAdd BLAST50
Domaini803 – 991MACPFInterPro annotationAdd BLAST189

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHIU Eukaryota
ENOG4110VB2 LUCA
GeneTreeiENSGT00390000003140
HOGENOMiHOG000034112
HOVERGENiHBG050597

Family and domain databases

CDDicd00063 FN3, 1 hit
InterProiView protein in InterPro
IPR026995 Astrotactin
IPR000742 EGF-like_dom
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR020864 MACPF
PANTHERiPTHR16592 PTHR16592, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 3 hits
SM00457 MACPF, 1 hit
SUPFAMiSSF49265 SSF49265, 2 hits

Sequencei

Sequence statusi: Complete.

B1AJS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALAGLCALL ACCWGPAAVL ATAAGDVDPS KELECKLKSI TVSALPFLRE
60 70 80 90 100
NDLSIMHSPS ASEPKLLFSV RNDFPGEMVV VDDLENTELP YFVLEISGNT
110 120 130 140 150
EDIPLVRWRQ QWLENGTLLF HIHHQDGAPS LPGQDPTEEP QHESAEEELR
160 170 180 190 200
ILHISVMGGM IALLLSILCL VMILYTRRRW CKRRRVPQPQ KSASAEAANE
210 220 230 240 250
IHYIPSVLIG GHGRESLRNA RVQGHNSSGT LSIRETPILD GYEYDITDLR
260 270 280 290 300
HHLQRECMNG GEDFASQVTR TLDSLQGCNE KSGMDLTPGS DNAKLSLMNK
310 320 330 340 350
YKDNIIATSP VDSNHQQATL LSHTSSSQRK RINNKARAGS AFLNPEGDSG
360 370 380 390 400
TEAENDPQLT FYTDPSRSRR RSRVGSPRSP VNKTTLTLIS ITSCVIGLVC
410 420 430 440 450
SSHVNCPLVV KITLHVPEHL IADGSRFILL EGSQLDASDW LNPAQVVLFS
460 470 480 490 500
QQNSSGPWAM DLCARRLLDP CEHQCDPETG ECLCYEGYMK DPVHKHLCIR
510 520 530 540 550
NEWGTNQGPW PYTIFQRGFD LVLGEQPSDK IFRFTYTLGE GMWLPLSKSF
560 570 580 590 600
VIPPAELAIN PSAKCKTDMT VMEDAVEVRE ELMTSSSFDS LEVLLDSFGP
610 620 630 640 650
VRDCSKDNGG CSKNFRCISD RKLDSTGCVC PSGLSPMKDS SGCYDRHIGV
660 670 680 690 700
DCSDGFNGGC EQLCLQQMAP FPDDPTLYNI LMFCGCIEDY KLGVDGRSCQ
710 720 730 740 750
LITETCPEGS DCGESRELPM NQTLFGEMFF GYNNHSKEVA AGQVLKGTFR
760 770 780 790 800
QNNFARGLDQ QLPDGLVVAT VPLENQCLEE ISEPTPDPDF LTGMVNFSEV
810 820 830 840 850
SGYPVLQHWK VRSVMYHIKL NQVAISQALS NALHSLDGAT SRADFVALLD
860 870 880 890 900
QFGNHYIQEA IYGFEESCSI WYPNKQVQRR LWLEYEDISK GNSPSDESEE
910 920 930 940 950
RERDPKVLTF PEYITSLSDS GTKHMAAGVR MECHSKGRCP SSCPLCHVTS
960 970 980 990 1000
SPDTPAEPVL LEVTKAAPIY ELVTNNQTQR LLQEATMSSL WCSGTGDVIE
1010 1020 1030 1040 1050
DWCRCDSTAF GADGLPTCAP LPQPVLRLST VHEPSSTLVV LEWEHSEPPI
1060 1070 1080 1090 1100
GVQIVDYLLR QEKVTDRMDH SKVETETVLS FVDDIISGAK SPCAMPSQVP
1110 1120 1130 1140 1150
DKQLTTISLI IRCLEPDTIY MFTLWGVDNT GRRSRPSDVI VKTPCPVVDD
1160 1170 1180 1190 1200
VKAQEIADKI YNLFNGYTSG KEQQTAYNTL LDLGSPTLHR VLYHYNQHYE
1210 1220
SFGEFTWRCE DELGPRLPAC WDSQRSCR
Length:1,228
Mass (Da):136,486
Last modified:April 8, 2008 - v1
Checksum:iAC672AE9B387D2D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021398 Genomic DNA No translation available.
AL022145 Genomic DNA No translation available.
AL031290 Genomic DNA No translation available.
AL136983 Genomic DNA No translation available.
KF454939 Genomic DNA No translation available.
KF455086 Genomic DNA No translation available.
RefSeqiNP_001273093.1, NM_001286164.1
UniGeneiHs.495897

Genome annotation databases

EnsembliENST00000367657; ENSP00000356629; ENSG00000152092
GeneIDi460
UCSCiuc001glb.3 human

Similar proteinsi

Entry informationi

Entry nameiB1AJS1_HUMAN
AccessioniPrimary (citable) accession number: B1AJS1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health