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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Ureaplasma parvum serovar 3 (strain ATCC 27815 / 27 / NCTC 11736)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei42 – 421NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciUPAR505682:GHAZ-373-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:UPA3_0370
OrganismiUreaplasma parvum serovar 3 (strain ATCC 27815 / 27 / NCTC 11736)
Taxonomic identifieri505682 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeUreaplasma

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 227227tRNA pseudouridine synthase BPRO_1000084711Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliB1AIZ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231223.
KOiK03177.
OMAiPLNWTSF.
OrthoDBiEOG6358D3.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

B1AIZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAISKNIII INKPIKWTSN DVVQKVKRVI GAKKVGHAGT LDPNASGVLV
60 70 80 90 100
LGINEGTKLL TKLILDNKSY IAEIKFGTST NTYDAAGEIV SSTNRMVTLT
110 120 130 140 150
EVTKIVKDFY KNDYWQKPPQ FSALKINGQK AYVLARQKVD FEIAPRLVKI
160 170 180 190 200
FKYQIMDFNY EKQILKISLH VSKGFYVRSF AVDLATKINN LAHLLTLIRT
210 220
QSGPFEIKDA IEIEQVYDYW NNINKYL
Length:227
Mass (Da):25,765
Last modified:April 8, 2008 - v1
Checksum:iFA1CADC357D6AD36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000942 Genomic DNA. Translation: ACA32964.1.
RefSeqiWP_006688525.1. NC_010503.1.

Genome annotation databases

EnsemblBacteriaiACA32964; ACA32964; UPA3_0370.
GeneIDi875949.
KEGGiupa:UPA3_0370.
PATRICi20532964. VBIUrePar123156_0360.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000942 Genomic DNA. Translation: ACA32964.1.
RefSeqiWP_006688525.1. NC_010503.1.

3D structure databases

ProteinModelPortaliB1AIZ3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA32964; ACA32964; UPA3_0370.
GeneIDi875949.
KEGGiupa:UPA3_0370.
PATRICi20532964. VBIUrePar123156_0360.

Phylogenomic databases

HOGENOMiHOG000231223.
KOiK03177.
OMAiPLNWTSF.
OrthoDBiEOG6358D3.

Enzyme and pathway databases

BioCyciUPAR505682:GHAZ-373-MONOMER.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Ureaplasma parvum serovar 3."
    Methe B.A., Glass J., Waites K., Shrivastava S.
    Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27815 / 27 / NCTC 11736.

Entry informationi

Entry nameiTRUB_UREP2
AccessioniPrimary (citable) accession number: B1AIZ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: January 20, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.