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B1AH87

- B1AH87_HUMAN

UniProt

B1AH87 - B1AH87_HUMAN

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Protein
Submitted name:

Putative peripheral benzodiazepine receptor-related protein

Gene
TSPO
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. androgen binding Source: Ensembl
  2. benzodiazepine receptor activity Source: Ensembl

GO - Biological processi

  1. adrenal gland development Source: Ensembl
  2. aging Source: Ensembl
  3. behavioral response to pain Source: Ensembl
  4. cellular hypotonic response Source: Ensembl
  5. cellular response to lipopolysaccharide Source: Ensembl
  6. cellular response to zinc ion Source: Ensembl
  7. chloride transport Source: Ensembl
  8. contact inhibition Source: Ensembl
  9. glial cell migration Source: Ensembl
  10. negative regulation of glial cell proliferation Source: Ensembl
  11. negative regulation of nitric oxide biosynthetic process Source: Ensembl
  12. negative regulation of tumor necrosis factor production Source: Ensembl
  13. peripheral nervous system axon regeneration Source: Ensembl
  14. positive regulation of apoptotic process Source: Ensembl
  15. positive regulation of calcium ion transport Source: Ensembl
  16. positive regulation of glial cell proliferation Source: Ensembl
  17. positive regulation of mitochondrial depolarization Source: Ensembl
  18. positive regulation of necrotic cell death Source: Ensembl
  19. positive regulation of reactive oxygen species metabolic process Source: Ensembl
  20. regulation of steroid biosynthetic process Source: Ensembl
  21. response to drug Source: Ensembl
  22. response to manganese ion Source: Ensembl
  23. response to progesterone Source: Ensembl
  24. response to testosterone Source: Ensembl
  25. response to vitamin B1 Source: Ensembl
  26. steroid biosynthetic process Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative peripheral benzodiazepine receptor-related proteinImported
Gene namesi
Name:TSPOImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 22

Organism-specific databases

HGNCiHGNC:1158. TSPO.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: HPA
  2. integral component of membrane Source: InterPro
  3. intracellular membrane-bounded organelle Source: HPA
  4. mitochondrial outer membrane Source: Ensembl
  5. mitochondrion Source: HPA
  6. nuclear membrane Source: HPA
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB1AH87.

Expressioni

Gene expression databases

ArrayExpressiB1AH87.

Structurei

3D structure databases

ProteinModelPortaliB1AH87.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000224659.
HOVERGENiHBG001296.

Family and domain databases

InterProiIPR004307. TspO_MBR.
[Graphical view]
PANTHERiPTHR10057. PTHR10057. 1 hit.
PfamiPF03073. TspO_MBR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B1AH87-1 [UniParc]FASTAAdd to Basket

« Hide

MAPPWVPAMG FTLAPSLGCF VGSRFVHGEG LRWYAGLQKP SWHPPHWVLG    50
PVWGTLYSAM GYGSYLVWKE LGGFTEKAVV PLGLYTGQLA LNWAWPPIFF 100
GARQMGW 107
Length:107
Mass (Da):11,896
Last modified:April 8, 2008 - v1
Checksum:i26DF39D8A64DEEB1
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei107 – 1071Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z82214 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000428336; ENSP00000405685; ENSG00000100300.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z82214 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali B1AH87.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B1AH87.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000428336 ; ENSP00000405685 ; ENSG00000100300 .

Organism-specific databases

HGNCi HGNC:1158. TSPO.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000224659.
HOVERGENi HBG001296.

Miscellaneous databases

ChiTaRSi TSPO. human.
NextBioi 35466364.

Gene expression databases

ArrayExpressi B1AH87.

Family and domain databases

InterProi IPR004307. TspO_MBR.
[Graphical view ]
PANTHERi PTHR10057. PTHR10057. 1 hit.
Pfami PF03073. TspO_MBR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 22."
    Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M.
    , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
    Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiB1AH87_HUMAN
AccessioniPrimary (citable) accession number: B1AH87
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: July 9, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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