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Protein
Submitted name:

Chorionic somatomammotropin hormone 1

Gene

CSH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHormoneUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Chorionic somatomammotropin hormone 1Imported
Submitted name:
Chorionic somatomammotropin hormone 1 isoform 3Imported
Submitted name:
HCG1749481, isoform CRA_dImported
Submitted name:
HCG1749481, isoform CRA_wImported
Submitted name:
HCG1749481, isoform CRA_yImported
Gene namesi
Name:CSH1Imported
ORF Names:hCG_1749481Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000136488.14.
HGNCiHGNC:2440. CSH1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000136488.
PharmGKBiPA26943.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_501010475227 – 122Sequence analysisAdd BLAST96

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSG00000136488.
ExpressionAtlasiB1A4H2. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiB1A4H2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the somatotropin/prolactin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IFR6. Eukaryota.
ENOG4111HU8. LUCA.
GeneTreeiENSGT00730000111012.
HOGENOMiHOG000068443.
HOVERGENiHBG011318.

Family and domain databases

InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR001400. Somatotropin/Prolactin.
IPR018116. Somatotropin_CS.
PANTHERiPTHR11417. PTHR11417. 2 hits.
PfamiView protein in Pfam
PF00103. Hormone_1. 1 hit.
PRINTSiPR00836. SOMATOTROPIN.
SUPFAMiSSF47266. SSF47266. 2 hits.
PROSITEiView protein in PROSITE
PS00338. SOMATOTROPIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B1A4H2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPGSRTSLL LAFALLCLPW LQEAGAVQTV PLSRLFDHAM LQAHRAHQLA
60 70 80 90 100
IDTYQEFRLE DGSRRTGQIL KQTYSKFDTN SHNHDALLKN YGLLYCFRKD
110 120
MDKVETFLRM VQCRSVEGSC GF
Length:122
Mass (Da):13,940
Last modified:April 8, 2008 - v1
Checksum:i6D2A0B0C810AB615
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei122Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC040958 Genomic DNA. No translation available.
AC127029 Genomic DNA. No translation available.
EU421714 Genomic DNA. Translation: ABZ88718.1.
CH471109 Genomic DNA. Translation: EAW94236.1.
CH471109 Genomic DNA. Translation: EAW94257.1.
CH471109 Genomic DNA. Translation: EAW94259.1.
UniGeneiHs.654390.

Genome annotation databases

EnsembliENST00000453363; ENSP00000402517; ENSG00000136488.
UCSCiuc060ist.1. human.

Similar proteinsi

Entry informationi

Entry nameiB1A4H2_HUMAN
AccessioniPrimary (citable) accession number: B1A4H2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 25, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported