Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Growth hormone 1 isoform 1

Gene

GH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHormoneUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Growth hormone 1 isoform 1Imported
Submitted name:
Growth hormone B5Imported
Submitted name:
HCG1749481, isoform CRA_sImported
Gene namesi
Name:GH1Imported
Synonyms:GHB5Imported
ORF Names:hCG_1749481Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000259384.6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA171

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_501429818527 – 217Sequence analysisAdd BLAST191

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSG00000259384
ExpressionAtlasiB1A4G6 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiB1A4G6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the somatotropin/prolactin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IFR6 Eukaryota
ENOG4111HU8 LUCA
HOVERGENiHBG011318
KOiK05438
OMAiTYLRVMK
OrthoDBiEOG091G0KPU

Family and domain databases

InterProiView protein in InterPro
IPR009079 4_helix_cytokine-like_core
IPR001400 Somatotropin/Prolactin
IPR018116 Somatotropin_CS
PANTHERiPTHR11417 PTHR11417, 1 hit
PfamiView protein in Pfam
PF00103 Hormone_1, 1 hit
PRINTSiPR00836 SOMATOTROPIN
SUPFAMiSSF47266 SSF47266, 1 hit
PROSITEiView protein in PROSITE
PS00266 SOMATOTROPIN_1, 1 hit
PS00338 SOMATOTROPIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

B1A4G6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATGSRTSLL LAFGLLCLPW LQEGSAFPTI PLSRLFDNAM LRAHRLHQLA
60 70 80 90 100
FDTYQEFEEA YIPKEQKYSF LQNPQTSLCF SESIPTPSNR EETQQKSNLE
110 120 130 140 150
LLRISLLLIQ SWLEPVQFLR SVFANSLVYG ASDSNVYDLL KDLEEGIQTL
160 170 180 190 200
MGRLEDGSPR TGQIFKQTYS KFDTNSHNDD ALLKNYGLLY CFRKDMDKVE
210
TFLRIVQCRS VEGSCGF
Length:217
Mass (Da):24,847
Last modified:April 8, 2008 - v1
Checksum:i72CC15AF4ED1C51A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU421712 Genomic DNA Translation: ABZ88711.1
LM644140 mRNA Translation: CDW51387.1
CH471109 Genomic DNA Translation: EAW94251.1
RefSeqiNP_000506.2, NM_000515.4
UniGeneiHs.655229

Genome annotation databases

GeneIDi2688
KEGGihsa:2688

Similar proteinsi

Entry informationi

Entry nameiB1A4G6_HUMAN
AccessioniPrimary (citable) accession number: B1A4G6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health