Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Vimentin

Gene

VIM

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
VimentinImported
Submitted name:
Vimentin variant 4Imported
Gene namesi
Name:VIMImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000026025.13
HGNCiHGNC:12692 VIM

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Intermediate filamentUniRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000026025

PTM / Processingi

Proteomic databases

MaxQBiB0YJC5
PeptideAtlasiB0YJC5

Expressioni

Gene expression databases

BgeeiENSG00000026025

Interactioni

Protein-protein interaction databases

IntActiB0YJC5, 1 interactor

Structurei

3D structure databases

SMRiB0YJC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili7 – 73Sequence analysisAdd BLAST67
Coiled coili113 – 207Sequence analysisAdd BLAST95

Sequence similaritiesi

Belongs to the intermediate filament family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IFZ1 Eukaryota
ENOG410XRBS LUCA
GeneTreeiENSGT00910000143989
HOVERGENiHBG013015

Family and domain databases

InterProiView protein in InterPro
IPR001664 IF
IPR018039 Intermediate_filament_CS
IPR027699 Vimentin
PANTHERiPTHR23239 PTHR23239, 1 hit
PTHR23239:SF27 PTHR23239:SF27, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
SMARTiView protein in SMART
SM01391 Filament, 1 hit
PROSITEiView protein in PROSITE
PS00226 IF, 1 hit

Sequencei

Sequence statusi: Complete.

B0YJC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNCFRLQEE MLQREEAENT LQSFRQDVDN ASLARLDLER KVESLQEEIA
60 70 80 90 100
FLKKLHEEEI QELQAQIQEQ HVQIDVDVSK PDLTAALRDV RQQYESVAAK
110 120 130 140 150
NLQEAEEWYK SKFADLSEAA NRNNDALRQA KQESTEYRRQ VQSLTCEVDA
160 170 180 190 200
LKGTNESLER QMREMEENFA VEAANYQDTI GRLQDEIQNM KEEMARHLRE
210 220
YQDLLNVKMA LDIEIATYRK LLEGEESR
Length:228
Mass (Da):26,859
Last modified:September 2, 2008 - v1
Checksum:i26380E0255646F0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133415 Genomic DNA No translation available.
EF445046 Genomic DNA Translation: ACA06100.1
UniGeneiHs.455493
Hs.691131
Hs.728090

Genome annotation databases

EnsembliENST00000469543; ENSP00000431702; ENSG00000026025
UCSCiuc057sbf.1 human

Similar proteinsi

Entry informationi

Entry nameiB0YJC5_HUMAN
AccessioniPrimary (citable) accession number: B0YJC5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: April 25, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health