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Protein
Submitted name:

Sodium channel beta-4 subunit

Gene

SCN4B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelImported
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Sodium channel beta-4 subunitImported
Submitted name:
Sodium channel, voltage-gated, type IV, beta, isoform CRA_bImported
Submitted name:
cDNA, FLJ95353, Homo sapiens sodium channel, voltage-gated, type IV, beta (SCN4B),mRNAImported
Gene namesi
Name:SCN4BImported
ORF Names:hCG_1646677Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000177098.8.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei162 – 183HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35007.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_501010471931 – 228Sequence analysisAdd BLAST198

Expressioni

Gene expression databases

BgeeiENSG00000177098.
ExpressionAtlasiB0YJ93. baseline and differential.

Structurei

3D structure databases

SMRiB0YJ93.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 148Ig-likeInterPro annotationAdd BLAST123

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IXQZ. Eukaryota.
ENOG4111PJ2. LUCA.
HOVERGENiHBG056581.
KOiK04848.
OMAiREKKKEC.
OrthoDBiEOG091G0MQV.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
IPR000920. Myelin_P0-rel.
PANTHERiPTHR13869. PTHR13869. 1 hit.
PfamiView protein in Pfam
PF07686. V-set. 1 hit.
SMARTiView protein in SMART
SM00409. IG. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.

Sequencei

Sequence statusi: Complete.

B0YJ93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGAGDGGKA PARWLGTGLL GLFLLPVTLS LEVSVGKATD IYAVNGTEIL
60 70 80 90 100
LPCTFSSCFG FEDLHFRWTY NSSDAFKILI EGTVKNEKSD PKVTLKDDDR
110 120 130 140 150
ITLVGSTKEK MNNISIVLRD LEFSDTGKYT CHVKNPKENN LQHHATIFLQ
160 170 180 190 200
VVDRLEEVDN TVTLIILAVV GGVIGLLILI LLIKKLIIFI LKKTREKKKE
210 220
CLVSSSGNDN TENGLPGSKA EEKPPSKV
Length:228
Mass (Da):24,969
Last modified:April 8, 2008 - v1
Checksum:i2F17E1210E8EFEF8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF445029 Genomic DNA. Translation: ACA06071.1.
AK314531 mRNA. Translation: BAG37123.1.
CH471065 Genomic DNA. Translation: EAW67352.1.
RefSeqiNP_777594.1. NM_174934.3.
UniGeneiHs.65239.

Genome annotation databases

GeneIDi6330.
KEGGihsa:6330.

Similar proteinsi

Entry informationi

Entry nameiB0YJ93_HUMAN
AccessioniPrimary (citable) accession number: B0YJ93
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 27, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.