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Protein
Submitted name:

Sodium channel beta-4 subunit

Gene

SCN4B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelImported
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Sodium channel beta-4 subunitImported
Submitted name:
Sodium channel, voltage-gated, type IV, beta, isoform CRA_bImported
Submitted name:
cDNA, FLJ95353, Homo sapiens sodium channel, voltage-gated, type IV, beta (SCN4B),mRNAImported
Gene namesi
Name:SCN4BImported
ORF Names:hCG_1646677Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000177098.8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei162 – 183HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35007

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_501429817031 – 228Sequence analysisAdd BLAST198

Proteomic databases

PRIDEiB0YJ93

Expressioni

Gene expression databases

BgeeiENSG00000177098
ExpressionAtlasiB0YJ93 baseline and differential

Structurei

3D structure databases

SMRiB0YJ93
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 148Ig-likeInterPro annotationAdd BLAST123

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IXQZ Eukaryota
ENOG4111PJ2 LUCA
HOVERGENiHBG056581
KOiK04848
OMAiREKKKEC
OrthoDBiEOG091G0MQV

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
IPR000920 Myelin_P0-rel
PANTHERiPTHR13869 PTHR13869, 1 hit
PfamiView protein in Pfam
PF07686 V-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

B0YJ93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGAGDGGKA PARWLGTGLL GLFLLPVTLS LEVSVGKATD IYAVNGTEIL
60 70 80 90 100
LPCTFSSCFG FEDLHFRWTY NSSDAFKILI EGTVKNEKSD PKVTLKDDDR
110 120 130 140 150
ITLVGSTKEK MNNISIVLRD LEFSDTGKYT CHVKNPKENN LQHHATIFLQ
160 170 180 190 200
VVDRLEEVDN TVTLIILAVV GGVIGLLILI LLIKKLIIFI LKKTREKKKE
210 220
CLVSSSGNDN TENGLPGSKA EEKPPSKV
Length:228
Mass (Da):24,969
Last modified:April 8, 2008 - v1
Checksum:i2F17E1210E8EFEF8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF445029 Genomic DNA Translation: ACA06071.1
AK314531 mRNA Translation: BAG37123.1
CH471065 Genomic DNA Translation: EAW67352.1
RefSeqiNP_777594.1, NM_174934.3
UniGeneiHs.65239

Genome annotation databases

GeneIDi6330
KEGGihsa:6330

Similar proteinsi

Entry informationi

Entry nameiB0YJ93_HUMAN
AccessioniPrimary (citable) accession number: B0YJ93
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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