B0YJ33 (B0YJ33_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Laminin alpha-3 chain variant 2 EMBL ACA06011.1

Submitted name:
Laminin subunit alpha-3 Ensembl ENSP00000269217

Gene names

Name:

LAMA3 Ensembl ENSP00000269217 EMBL ACA06011.1

Organism

Homo sapiens (Human) [Reference proteome] EMBL ACA06011.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1724 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: InterPro regulation of cell adhesion Inferred from electronic annotation. Source: InterPro regulation of cell migration Inferred from electronic annotation. Source: InterPro regulation of embryonic development Inferred from electronic annotation. Source: InterPro
Cellular_component	laminin-1 complex Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0YJ33 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 0477C729951763A5	FASTA	1,724	190,491
	10 20 30 40 50 60 MPPAVRRSAC SMGWLWIFGA ALGQCLGYSS QQQRVPFLQP PGQSQLQASY VEFRPSQGCS 70 80 90 100 110 120 PGYYRDHKGL YTGRCVPCNC NGHSNQCQDG SGICVNCQHN TAGEHCERCQ EGYYGNAVHG 130 140 150 160 170 180 SCRACPCPHT NSFATGCVVN GGDVRCSCKA GYTGTQCERC APGYFGNPQK FGGSCQPCSC 190 200 210 220 230 240 NSNGQLGSCH PLTGDCINQE PKDSSPAEEC DDCDSCVMTL LNDLATMGEQ LRLVKSQLQG 250 260 270 280 290 300 LSASAGLLEQ MRHMETQAKD LRNQLLNYRS AISNHGSKIE GLERELTDLN QEFETLQEKA 310 320 330 340 350 360 QVNSRKAQTL NNNVNRATQS AKELDVKIKN VIRNVHILLK QISGTDGEGN NVPSGDFSRE 370 380 390 400 410 420 WAEAQRMMRE LRNRNFGKHL REAEADKRES QLLLNRIRTW QKTHQGENNG LANSIRDSLN 430 440 450 460 470 480 EYEAKLSDLR ARLQEAAAQA KQANGLNQEN ERALGAIQRQ VKEINSLQSD FTKYLTTADS 490 500 510 520 530 540 SLLQTNIALQ LMEKSQKEYE KLAASLNEAR QELSDKVREL SRSAGKTSLV EEAEKHARSL 550 560 570 580 590 600 QELAKQLEEI KRNASGDELV RCAVDAATAY ENILNAIKAA EDAANRAASA SESALQTVIK 610 620 630 640 650 660 EDLPRKAKTL SSNSDKLLNE AKMTQKKLKQ EVSPALNNLQ QTLNIVTVQK EVIDTNLTTL 670 680 690 700 710 720 RDGLHGIQRG DIDAMISSAK SMVRKANDIT DEVLDGLNPI QTDVERIKDT YGRTQNEDFK 730 740 750 760 770 780 KALTDADNSV NKLTNKLPDL WRKIESINQQ LLPLGNISDN MDRIRELIQQ ARDAASKVAV 790 800 810 820 830 840 PMRFNGKSGV EVRLPNDLED LKGYTSLSLF LQRPNSRENG GTENMFVMYL GNKDASRDYI 850 860 870 880 890 900 GMAVVDGQLT CVYNLGDREA ELQVDQILTK SETKEAVMDR VKFQRIYQFA RLNYTKGATS 910 920 930 940 950 960 SKPETPGVYD MDGRNSNTLL NLDPENVVFY VGGYPPDFKL PSRLSFPPYK GCIELDDLNE 970 980 990 1000 1010 1020 NVLSLYNFKK TFNLNTTEVE PCRRRKEESD KNYFEGTGYA RVPTQPHAPI PTFGQTIQTT 1030 1040 1050 1060 1070 1080 VDRGLLFFAE NGDRFISLNI EDGKLMVRYK LNSELPKERG VGDAINNGRD HSIQIKIGKL 1090 1100 1110 1120 1130 1140 QKRMWINVDV QNTIIDGEVF DFSTYYLGGI PIAIRERFNI STPAFRGCMK NLKKTSGVVR 1150 1160 1170 1180 1190 1200 LNDTVGVTKK CSEDWKLVRS ASFSRGGQLS FTDLGLPPTD HLQASFGFQT FQPSGILLDH 1210 1220 1230 1240 1250 1260 QTWTRNLQVT LEDGYIELST SDSGSPIFKS PQTYMDGLLH YVSVISDNSG LRLLIDDQLL 1270 1280 1290 1300 1310 1320 RNSKRLKHIS SSRQSLRLGG SNFEGCISNV FVQRLSLSPE VLDLTSNSLK RDVSLGGCSL 1330 1340 1350 1360 1370 1380 NKPPFLMLLK GSTRFNKTKT FRINQLLQDT PVASPRSVKV WQDACSPLPK TQANHGALQF 1390 1400 1410 1420 1430 1440 GDIPTSHLLF KLPQELLKPR SQFAVDMQTT SSRGLVFHTG TKNSFMALYL SKGRLVFALG 1450 1460 1470 1480 1490 1500 TDGKKLRIKS KEKCNDGKWH TVVFGHDGEK GRLVVDGLRA REGSLPGNST ISIRAPVYLG 1510 1520 1530 1540 1550 1560 SPPSGKPKSL PTNSFVGCLK NFQLDSKPLY TPSSSFGVSS CLGGPLEKGI YFSEEGGHVV 1570 1580 1590 1600 1610 1620 LAHSVLLGPE FKLVFSIRPR SLTGILIHIG SQPGKHLCVY LEAGKVTASM DSGAGGTSTS 1630 1640 1650 1660 1670 1680 VTPKQSLCDG QWHSVAVTIK QHILHLELDT DSSYTAGQIP FPPASTQEPL HLGGAPANLT 1690 1700 1710 1720 TLRIPVWKSF FGCLRNIHVN HIPVPVTEAL EVQGPVSLNG CPDQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequence and analysis of human chromosome 18." Nusbaum C., Zody M.C., Borowsky M.L., Kamal M., Kodira C.D., Taylor T.D., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Abouelleil A., Allen N.R., Anderson S., Bloom T., Bugalter B., Butler J. , Cook A., DeCaprio D., Engels R., Garber M., Gnirke A., Hafez N., Hall J.L., Norman C.H., Itoh T., Jaffe D.B., Kuroki Y., Lehoczky J., Lui A., Macdonald P., Mauceli E., Mikkelsen T.S., Naylor J.W., Nicol R., Nguyen C., Noguchi H., O'Leary S.B., O'Neill K., Piqani B., Smith C.L., Talamas J.A., Topham K., Totoki Y., Toyoda A., Wain H.M., Young S.K., Zeng Q., Zimmer A.R., Fujiyama A., Hattori M., Birren B.W., Sakaki Y., Lander E.S. Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Stockwell T.B., Busam D.A., Ferriera S.M., Brownley A.N., Strausberg R.L., Kirkness E.F., Rogers Y.-H., Levy S. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC010754 Genomic DNA. No translation available. AC067796 Genomic DNA. No translation available. AC090366 Genomic DNA. No translation available. EF444992 Genomic DNA. Translation: ACA06011.1.
IPI	IPI00790908.
RefSeq	NP_000218.2. NM_000227.3.
UniGene	Hs.436367.
3D structure databases
ModBase	Search...
Protocols and materials databases
DNASU	3909.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000269217; ENSP00000269217; ENSG00000053747.
GeneID	3909.
KEGG	hsa:3909.
UCSC	uc002kus.4. human.
Organism-specific databases
CTD	3909.
HGNC	HGNC:6483. LAMA3.
PharmGKB	PA30272.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000048708.
HOVERGEN	HBG100777.
KO	K06240.
Family and domain databases
Gene3D	2.60.120.200. 5 hits.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR002049. EGF_laminin. IPR001791. Laminin_G. IPR009254. Laminin_I. IPR010307. Laminin_II. [Graphical view]
Pfam	PF00053. Laminin_EGF. 2 hits. PF02210. Laminin_G_2. 5 hits. PF06008. Laminin_I. 1 hit. PF06009. Laminin_II. 1 hit. [Graphical view]
SMART	SM00180. EGF_Lam. 2 hits. SM00282. LamG. 5 hits. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 5 hits.
PROSITE	PS01248. EGF_LAM_1. 2 hits. PS50027. EGF_LAM_2. 2 hits. PS50025. LAM_G_DOMAIN. 5 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	LAMA3. human.
GenomeRNAi	3909.
NextBio	15345.

Entry information

Entry name

B0YJ33_HUMAN

Accession

Primary (citable) accession number: B0YJ33

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	May 29, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.