B0YJ32 (B0YJ32_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Laminin alpha-3 chain variant 1 EMBL ACA06010.1

Gene names

Name:

LAMA3 EMBL ACA06010.1

Organism

Homo sapiens (Human) EMBL ACA06010.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	3335 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Laminin EGF-like domain SAAS SAAS008211 Repeat SAAS SAAS002049
PTM	Disulfide bond SAAS SAAS008211
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: InterPro regulation of cell adhesion Inferred from electronic annotation. Source: InterPro regulation of cell migration Inferred from electronic annotation. Source: InterPro regulation of embryonic development Inferred from electronic annotation. Source: InterPro
Cellular_component	laminin-1 complex Inferred from electronic annotation. Source: InterPro laminin-5 complex Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0YJ32 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 6736568CBCF924F6	FASTA	3,335	366,950
	10 20 30 40 50 60 MAAAARPRGR ALGPVLPPTP LLLLVLRVLP ACGATARDPG AAAGLSLHPT YFNLAEAARI 70 80 90 100 110 120 WATATCGERG PGEGRPQPEL YCKLVGGPTA PGSGHTIQGQ FCDYCNSEDP RKAHPVTNAI 130 140 150 160 170 180 DGSERWWQSP PLSSGTQYNR VNLTLDLGQL FHVAYILIKF ANSPRPDLWV LERSVDFGST 190 200 210 220 230 240 YSPWQYFAHS KVDCLKEFGR EANMAVTRDD DVLCVTEYSR IVPLENGEVV VSLINGRPGA 250 260 270 280 290 300 KNFTFSHTLR EFTKATNIRL RFLRTNTLLG HLISKAQRDP TVTRRYYYSI KDISIGGQCV 310 320 330 340 350 360 CNGHAEVCNI NNPEKLFRCE CQHHTCGETC DRCCTGYNQR RWRPAAWEQS HECEACNCHG 370 380 390 400 410 420 HASNCYYDPD VERQQASLNT QGIYAGGGVC INCQHNTAGV NCEQCAKGYY RPYGVPVDAP 430 440 450 460 470 480 DGCIPCSCDP EHADGCEQGS GRCHCKPNFH GDNCEKCAIG YYNFPFCLRI PIFPVSTPSS 490 500 510 520 530 540 EDPVAGDIKG NWCDCNLEGV LPEICDAHGR CLCRPGVEGP RCDTCRSGFY SFPICQACWC 550 560 570 580 590 600 SALGSYQMPC SSVTGQCECR PGVTGQRCDR CLSGAYDFPH CQGSSSACDP AGTINSNLGY 610 620 630 640 650 660 CQCKLHVEGP TCSRCKLLYW NLDKENPSGC SECKCHKAGT VSGTGECRQG DGDCHCKSHV 670 680 690 700 710 720 GGDSCDTCED GYFALEKSNY FGCQGCQCDI GGALSSMCSG PSGVCQCREH VVGKVCQRPE 730 740 750 760 770 780 NNYYFPDLHH MKYEIEDGST PNGRDLRFGF DPLAFPEFSW RGYAQMTSVQ NDVRITLNVG 790 800 810 820 830 840 KSSGSLFRVI LRYVNPGTEA VSGHITIYPS WGAAQSKEII FLPSKEPAFV TVPGNGFADP 850 860 870 880 890 900 FSITPGIWVA CIKAEGVLLD YLVLLPRDYY EASVLQLPVT EPCAYAGPPQ ENCLLYQHLP 910 920 930 940 950 960 VTRFPCTLAC EARHFLLDGE PRPVAVRQPT PAHPVMVDLS GREVELHLRL RIPQVGHYVV 970 980 990 1000 1010 1020 VVEYSTEAAQ LFVVDVNVKS SGSVLAGQVN IYSCNYSVLC RSAVIDHMSR IAMYELLADA 1030 1040 1050 1060 1070 1080 DIQLKGHMAR FLLHQVCIIP IEEFSAEYVR PQVHCIASYG RFVNQSATCV SLAHETPPTA 1090 1100 1110 1120 1130 1140 LILDVLSGRP FPHLPQQSSP SVDVLPGVTL KAPQNQVTLR GRVPHLGRYV FVIHFYQAAH 1150 1160 1170 1180 1190 1200 PTFPAQVSVD GGWPRAGSFH ASFCPHVLGC RDQVIAEGQI EFDISEPEVA ATVKVPEGKS 1210 1220 1230 1240 1250 1260 LVLVRVLVVP AENYDYQILH KKSMDKSLEF ITNCGKNSFY LDPQTASRFC KNSARSLVAF 1270 1280 1290 1300 1310 1320 YHKGALPCEC HPTGATGPHC SPEGGQCPCQ PNVIGRQCTR CATGHYGFPR CKPCSCGRRL 1330 1340 1350 1360 1370 1380 CEEMTGQCRC PPRTVRPQCE VCETHSFSFH PMAGCEGCNC SRRGTIEAAM PECDRDSGQC 1390 1400 1410 1420 1430 1440 RCKPRITGRQ CDRCASGFYR FPECVPCNCN RDGTEPGVCD PGTGACLCKE NVEGTECNVC 1450 1460 1470 1480 1490 1500 REGSFHLDPA NLKGCTSCFC FGVNNQCHSS HKRRTKFVDM LGWHLETADR VDIPVSFNPG 1510 1520 1530 1540 1550 1560 SNSMVADLQE LPATIHSASW VAPTSYLGDK VSSYGGYLTY QAKSFGLPGD MVLLEKKPDV 1570 1580 1590 1600 1610 1620 QLTGQHMSII YEETNTPRPD RLHHGRVHVV EGNFRHASSR APVSREELMT VLSRLADVRI 1630 1640 1650 1660 1670 1680 QGLYFTETQR LTLSEVGLEE ASDTGSGRIA LAVEICACPP AYAGDSCQGC SPGYYRDHKG 1690 1700 1710 1720 1730 1740 LYTGRCVPCN CNGHSNQCQD GSGICVNCQH NTAGEHCERC QEGYYGNAVH GSCRACPCPH 1750 1760 1770 1780 1790 1800 TNSFATGCVV NGGDVRCSCK AGYTGTQCER CAPGYFGNPQ KFGGSCQPCS CNSNGQLGSC 1810 1820 1830 1840 1850 1860 HPLTGDCINQ EPKDSSPAEE CDDCDSCVMT LLNDLATMGE QLRLVKSQLQ GLSASAGLLE 1870 1880 1890 1900 1910 1920 QMRHMETQAK DLRNQLLNYR SAISNHGSKI EGLERELTDL NQEFETLQEK AQVNSRKAQT 1930 1940 1950 1960 1970 1980 LNNNVNRATQ SAKELDVKIK NVIRNVHILL KQISGTDGEG NNVPSGDFSR EWAEAQRMMR 1990 2000 2010 2020 2030 2040 ELRNRNFGKH LREAEADKRE SQLLLNRIRT WQKTHQGENN GLANSIRDSL NEYEAKLSDL 2050 2060 2070 2080 2090 2100 RARLQEAAAQ AKQANGLNQE NERALGAIQR QVKEINSLQS DFTKYLTTAD SSLLQTNIAL 2110 2120 2130 2140 2150 2160 QLMEKSQKEY EKLAASLNEA RQELSDKVRE LSRSAGKTSL VEEAEKHARS LQELAKQLEE 2170 2180 2190 2200 2210 2220 IKRNASGDEL VRCAVDAATA YENILNAIKA AEDAANRAAS ASESALQTVI KEDLPRKAKT 2230 2240 2250 2260 2270 2280 LSSNSDKLLN EAKMTQKKLK QEVSPALNNL QQTLNIVTVQ KEVIDTNLTT LRDGLHGIQR 2290 2300 2310 2320 2330 2340 GDIDAMISSA KSMVRKANDI TDEVLDGLNP IQTDVERIKD TYGRTQNEDF KKALTDADNS 2350 2360 2370 2380 2390 2400 VNKLTNKLPD LWRKIESINQ QLLPLGNISD NMDRIRELIQ QARDAASKVA VPMRFNGKSG 2410 2420 2430 2440 2450 2460 VEVRLPNDLE DLKGYTSLSL FLQRPNSREN GGTENMFVMY LGNKDASRDY IGMAVVDGQL 2470 2480 2490 2500 2510 2520 TCVYNLGDRE AELQVDQILT KSETKEAVMD RVKFQRIYQF ARLNYTKGAT SSKPETPGVY 2530 2540 2550 2560 2570 2580 DMDGRNSNTL LNLDPENVVF YVGGYPPDFK LPSRLSFPPY KGCIELDDLN ENVLSLYNFK 2590 2600 2610 2620 2630 2640 KTFNLNTTEV EPCRRRKEES DKNYFEGTGY ARVPTQPHAP IPTFGQTIQT TVDRGLLFFA 2650 2660 2670 2680 2690 2700 ENGDRFISLN IEDGKLMVRY KLNSELPKER GVGDAINNGR DHSIQIKIGK LQKRMWINVD 2710 2720 2730 2740 2750 2760 VQNTIIDGEV FDFSTYYLGG IPIAIRERFN ISTPAFRGCM KNLKKTSGVV RLNDTVGVTK 2770 2780 2790 2800 2810 2820 KCSEDWKLVR SASFSRGGQL SFTDLGLPPT DHLQASFGFQ TFQPSGILLD HQTWTRNLQV 2830 2840 2850 2860 2870 2880 TLEDGYIELS TSDSGSPIFK SPQTYMDGLL HYVSVISDNS GLRLLIDDQL LRNSKRLKHI 2890 2900 2910 2920 2930 2940 SSSRQSLRLG GSNFEGCISN VFVQRLSLSP EVLDLTSNSL KRDVSLGGCS LNKPPFLMLL 2950 2960 2970 2980 2990 3000 KGSTRFNKTK TFRINQLLQD TPVASPRSVK VWQDACSPLP KTQANHGALQ FGDIPTSHLL 3010 3020 3030 3040 3050 3060 FKLPQELLKP RSQFAVDMQT TSSRGLVFHT GTKNSFMALY LSKGRLVFAL GTDGKKLRIK 3070 3080 3090 3100 3110 3120 SKEKCNDGKW HTVVFGHDGE KGRLVVDGLR AREGSLPGNS TISIRAPVYL GSPPSGKPKS 3130 3140 3150 3160 3170 3180 LPTNSFVGCL KNFQLDSKPL YTPSSSFGVS SCLGGPLEKG IYFSEEGGHV VLAHSVLLGP 3190 3200 3210 3220 3230 3240 EFKLVFSIRP RSLTGILIHI GSQPGKHLCV YLEAGKVTAS MDSGAGGTST SVTPKQSLCD 3250 3260 3270 3280 3290 3300 GQWHSVAVTI KQHILHLELD TDSSYTAGQI PFPPASTQEP LHLGGAPANL TTLRIPVWKS 3310 3320 3330 FFGCLRNIHV NHIPVPVTEA LEVQGPVSLN GCPDQ

References

[1]	Stockwell T.B., Busam D.A., Ferriera S.M., Brownley A.N., Strausberg R.L., Kirkness E.F., Rogers Y.-H., Levy S. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EF444992 Genomic DNA. Translation: ACA06010.1.
IPI	IPI00377045.
UniGene	Hs.436367.
3D structure databases
ProteinModelPortal	B0YJ32.
SMR	B0YJ32. Positions 44-427.
ModBase	Search...
Protein-protein interaction databases
STRING	B0YJ32.
Proteomic databases
PRIDE	B0YJ32.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000231235.
HOVERGEN	HBG052300.
Gene expression databases
ArrayExpress	B0YJ32.
Bgee	B0YJ32.
Family and domain databases
Gene3D	2.60.120.200. 5 hits.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR013032. EGF-like_CS. IPR002049. EGF_laminin. IPR009030. Growth_fac_rcpt. IPR018031. Laminin_B_subgr. IPR000034. Laminin_B_type_IV. IPR001791. Laminin_G. IPR009254. Laminin_I. IPR010307. Laminin_II. IPR008211. Laminin_N. [Graphical view]
Pfam	PF00052. Laminin_B. 1 hit. PF00053. Laminin_EGF. 12 hits. PF02210. Laminin_G_2. 5 hits. PF06008. Laminin_I. 1 hit. PF06009. Laminin_II. 1 hit. PF00055. Laminin_N. 1 hit. [Graphical view]
SMART	SM00180. EGF_Lam. 14 hits. SM00281. LamB. 1 hit. SM00282. LamG. 5 hits. SM00136. LamNT. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 5 hits. SSF57184. Grow_fac_recept. 1 hit.
PROSITE	PS00022. EGF_1. 12 hits. PS01248. EGF_LAM_1. 13 hits. PS50027. EGF_LAM_2. 14 hits. PS50025. LAM_G_DOMAIN. 5 hits. PS51115. LAMININ_IVA. 1 hit. PS51117. LAMININ_NTER. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	LAMA3. human.
NextBio	35466293.

Entry information

Entry name

B0YJ32_HUMAN

Accession

Primary (citable) accession number: B0YJ32

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	April 3, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.