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Protein
Submitted name:

CD3g antigen, gamma polypeptide (TiT3 complex)

Gene

CD3G

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CD3g antigen, gamma polypeptide (TiT3 complex)Imported
Submitted name:
T-cell surface glycoprotein CD3 gamma chainImported
Submitted name:
cDNA, FLJ94613, Homo sapiens CD3G antigen, gamma polypeptide (TiT3 complex) (CD3G),mRNAImported
Gene namesi
Name:CD3GImported
ORF Names:hCG_1646880Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000160654.9.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei112 – 137HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26217.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501108688523 – 182Sequence analysisAdd BLAST160

Expressioni

Gene expression databases

BgeeiENSG00000160654.

Structurei

3D structure databases

SMRiB0YIY5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 94IGc2InterPro annotationAdd BLAST58

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IWAX. Eukaryota.
ENOG410Y2TD. LUCA.
HOVERGENiHBG005278.
KOiK06452.
OMAiDRENDQY.
OrthoDBiEOG091G0MXQ.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR015484. CD3_esu/gsu/dsu.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR032052. Ig_4.
IPR003598. Ig_sub2.
IPR003110. Phos_immunorcpt_sig_ITAM.
PANTHERiPTHR10570. PTHR10570. 1 hit.
PfamiView protein in Pfam
PF16680. Ig_4. 1 hit.
PF02189. ITAM. 1 hit.
SMARTiView protein in SMART
SM00408. IGc2. 1 hit.
SM00077. ITAM. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiView protein in PROSITE
PS51055. ITAM_1. 1 hit.

Sequencei

Sequence statusi: Complete.

B0YIY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQGKGLAVL ILAIILLQGT LAQSIKGNHL VKVYDYQEDG SVLLTCDAEA
60 70 80 90 100
KNITWFKDGK MIGFLTEDKK KWNLGSNAKD PRGMYQCKGS QNKSKPLQVY
110 120 130 140 150
YRMCQNCIEL NAATISGFLF AEIVSIFVLA VGVYFIAGQD GVRQSRASDK
160 170 180
QTLLPNDQLY QPLKDREDDQ YSHLQGNQLR RN
Length:182
Mass (Da):20,469
Last modified:April 8, 2008 - v1
Checksum:iEE65C0186FB9872B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF444965 Genomic DNA. Translation: ACA05963.1.
AK313966 mRNA. Translation: BAG36681.1.
CH471065 Genomic DNA. Translation: EAW67368.1.
RefSeqiNP_000064.1. NM_000073.2.
XP_006719004.1. XM_006718941.2.
UniGeneiHs.2259.

Genome annotation databases

GeneIDi917.
KEGGihsa:917.

Similar proteinsi

Entry informationi

Entry nameiB0YIY5_HUMAN
AccessioniPrimary (citable) accession number: B0YIY5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 22, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.