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Protein
Submitted name:

Type III neuregulin 1

Gene

Nrg1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Type III neuregulin 1Imported
Gene namesi
Name:Nrg1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei76 – 9924HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiB0YIS0.

Expressioni

Gene expression databases

BgeeiB0YIS0.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000073546.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IEU9. Eukaryota.
ENOG4110ST7. LUCA.
HOVERGENiHBG006531.

Family and domain databases

InterProiIPR018250. NRG1.
[Graphical view]
PANTHERiPTHR11100:SF7. PTHR11100:SF7. 1 hit.

Sequencei

Sequence statusi: Fragment.

B0YIS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEIYPPDMSE GAGGRSSSPS TQLSADPSLD GLPAAEHMPD THTEDGRSPG
60 70 80 90 100
LLGLAVPCCV CLEAERLRGC LNSEKICIVP ILACLVSLCL CIAGLKWVFV
110 120 130 140 150
DKIFEYDSPT HLDPGGLGQD PVISLDPTAA SAVLVSSEAY TSPVSKAQSE
160 170 180 190 200
AEAHVTGQGD HVAVASEPSA VPTRKNRLSA FPPLHSTPPP FPSPARTPEV
210 220
RTPKSGTQPQ TTETNLQTAP KL
Length:222
Mass (Da):23,230
Last modified:April 8, 2008 - v1
Checksum:iF7081ABCA27FF8EA
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei222 – 2221Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF410152 Genomic DNA. Translation: ABN79386.1.
UniGeneiMm.153432.
Mm.460675.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF410152 Genomic DNA. Translation: ABN79386.1.
UniGeneiMm.153432.
Mm.460675.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000073546.

Proteomic databases

PaxDbiB0YIS0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IEU9. Eukaryota.
ENOG4110ST7. LUCA.
HOVERGENiHBG006531.

Gene expression databases

BgeeiB0YIS0.

Family and domain databases

InterProiIPR018250. NRG1.
[Graphical view]
PANTHERiPTHR11100:SF7. PTHR11100:SF7. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Type III Nrg1 is required for normal sensorimotor gating, memory related behaviors and cortico-striatal circuit components."
    Chen Y.-J.J., Johnson M.A., Lieberman M.D., Goodchild R., Rosoklija G., Gingrich J.A., Moore H., Dwork A.J., Talmage D.A., Role L.W.
    Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 129/SvEv x C57BL/6Imported.

Entry informationi

Entry nameiB0YIS0_MOUSE
AccessioniPrimary (citable) accession number: B0YIS0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: June 8, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.