B0YIS0 (B0YIS0_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Type III neuregulin 1 EMBL ABN79386.1

Gene names

Name:

Nrg1 EMBL ABN79386.1 MGI 96083

Organism

Mus musculus (Mouse) EMBL ABN79386.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	222 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	ERBB signaling pathway Inferred from electronic annotation. Source: Compara cardiac muscle cell myoblast differentiation Inferred from electronic annotation. Source: Compara cell proliferation Inferred from electronic annotation. Source: Compara cellular protein complex disassembly Inferred from electronic annotation. Source: Compara endocardial cell differentiation Inferred from electronic annotation. Source: Compara negative regulation of cardiac muscle cell apoptotic process Inferred from electronic annotation. Source: Compara negative regulation of secretion Inferred from electronic annotation. Source: Compara negative regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: Compara positive regulation of cardiac muscle cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of cell adhesion Inferred from electronic annotation. Source: Compara positive regulation of cell growth Inferred from electronic annotation. Source: Compara regulation of protein heterodimerization activity Inferred from electronic annotation. Source: Compara ventricular cardiac muscle cell differentiation Inferred from electronic annotation. Source: Compara ventricular trabecula myocardium morphogenesis Inferred from electronic annotation. Source: Compara
Cellular_component	apical plasma membrane Inferred from electronic annotation. Source: Compara extracellular space Inferred from electronic annotation. Source: Compara
Molecular_function	protein tyrosine kinase activator activity Inferred from electronic annotation. Source: Compara transcription cofactor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	222	1	EMBL ABN79386.1

Sequences

	Sequence		Length	Mass (Da)
	B0YIS0 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: F7081ABCA27FF8EA	FASTA	222	23,230
	10 20 30 40 50 60 MEIYPPDMSE GAGGRSSSPS TQLSADPSLD GLPAAEHMPD THTEDGRSPG LLGLAVPCCV 70 80 90 100 110 120 CLEAERLRGC LNSEKICIVP ILACLVSLCL CIAGLKWVFV DKIFEYDSPT HLDPGGLGQD 130 140 150 160 170 180 PVISLDPTAA SAVLVSSEAY TSPVSKAQSE AEAHVTGQGD HVAVASEPSA VPTRKNRLSA 190 200 210 220 FPPLHSTPPP FPSPARTPEV RTPKSGTQPQ TTETNLQTAP KL

References

[1]

"Type III Nrg1 is required for normal sensorimotor gating, memory related behaviors and cortico-striatal circuit components." Chen Y.-J.J., Johnson M.A., Lieberman M.D., Goodchild R., Rosoklija G., Gingrich J.A., Moore H., Dwork A.J., Talmage D.A., Role L.W. Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 129/SvEv x C57BL/6 EMBL ABN79386.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EF410152 Genomic DNA. Translation: ABN79386.1.
IPI	IPI00113865.
UniGene	Mm.153432. Mm.460675.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000073546. B0YIS0.
Proteomic databases
PaxDb	B0YIS0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	NOG47801.
HOVERGEN	HBG006531.
InParanoid	B0YIS0.
Gene expression databases
ArrayExpress	B0YIS0.
Bgee	B0YIS0.
Genevestigator	B0YIS0.
Family and domain databases
ProtoNet	Search...
Other
NextBio	35545604.

Entry information

Entry name

B0YIS0_MOUSE

Accession

Primary (citable) accession number: B0YIS0

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	April 3, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)