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B0YD91 (BGLE_ASPFC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase E

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase E
Cellobiase E
Gentiobiase E
Gene names
Name:bglE
ORF Names:AFUB_094720
OrganismNeosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus) [Complete proteome]
Taxonomic identifier451804 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length1033 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Cell membrane; Single-pass type II membrane protein By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentCell membrane
Membrane
   DomainSignal-anchor
Transmembrane
Transmembrane helix
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10331033Probable beta-glucosidase E
PRO_0000394871

Regions

Topological domain1 – 161161Cytoplasmic Potential
Transmembrane162 – 18221Helical; Signal-anchor for type II membrane protein; Potential
Topological domain183 – 1033851Extracellular Potential

Sites

Active site4461 By similarity

Amino acid modifications

Glycosylation2241N-linked (GlcNAc...) Potential
Glycosylation2321N-linked (GlcNAc...) Potential
Glycosylation4181N-linked (GlcNAc...) Potential
Glycosylation4891N-linked (GlcNAc...) Potential
Glycosylation5281N-linked (GlcNAc...) Potential
Glycosylation5931N-linked (GlcNAc...) Potential
Glycosylation9091N-linked (GlcNAc...) Potential
Glycosylation9181N-linked (GlcNAc...) Potential
Glycosylation9761N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
B0YD91 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 68768F797E72DE92

FASTA1,033113,423
        10         20         30         40         50         60 
MAPPDSTHGG SFRDHLKTND RSSTSKGKQR YSPLQEAIPE EISSFRSPSE YADTDSDSDL 

        70         80         90        100        110        120 
ERSGSYKLRP VDRYGSHHSS AFIPVIREEN GVETYLDSIT EAEQELLSAS KQYDLVDDDD 

       130        140        150        160        170        180 
SSDFDSDEEA TLRYRLKDRL KRRRARLQAW QPVKYARIWW RTLLAVVVTL VVVVWGFLSF 

       190        200        210        220        230        240 
AVSHREEPTV WPMVPSDSWF PSPKGGTLKH WEESYKKAQS LVRNMTLVEK VNITTGIGWQ 

       250        260        270        280        290        300 
MGLCVGNTGP ADIVKFPSLC LQDGPQGLRF ADHVSAFPAG ITTGSTWNRE LMRERGVAMG 

       310        320        330        340        350        360 
REARLKGVNV LLGPSMGPLG MMPAGGRNWE GFGSDPVLQA VAAAETIRGI QSNGVMATAK 

       370        380        390        400        410        420 
HFVMNEQEHF RQPFEWGIPT ALSSNVGDRA LHEVFAWPFA ESIRADVASV MCSYQMVNNS 

       430        440        450        460        470        480 
HACENSKLLN GILKDELGFQ GFVQSDWLAQ RSGINSALGG LDMSMPGDGL HWVDGKSLWG 

       490        500        510        520        530        540 
SELTRAVLNT SVPVERLNDM VTRIVAAWYH LGQDTWERPP PEGNGGPNFS SWTNDEVGWL 

       550        560        570        580        590        600 
HTGSNDGSYA RVNHYVDAQG TGPEAHSIIA RKVAAEGTVL LKNVDRTLPL SRNASSPSGG 

       610        620        630        640        650        660 
ILRVGIYGDD AGPALGPNAC PDRGCNQGTL ATGWGSGTVE FPYLVSPIEA LESAWSTEIE 

       670        680        690        700        710        720 
STAYLRNAVM PADAVDKDLC LVFVNADSGE GYISAGGIHG DRNDLFLQKG GDTLVRTVSS 

       730        740        750        760        770        780 
NCGGGQGKTV VVIHAVGPVV MESWIDLPGV HAVLLANLPG QESGNALVDV LFGEVDASGR 

       790        800        810        820        830        840 
LPYTIGKSLE DYGPGAQVLY EPNAPVPQVD FLDALYIDYR HFDRHNITPR FEFGFGLSYT 

       850        860        870        880        890        900 
TFELLDLSIS PLQQKSRSVP PRPADAVAPP VYDISLPDPA SALFPAGFQP VFKYIYPYLS 

       910        920        930        940        950        960 
NLDGTAPHNY SFYPKGYNET QRPSPAGGGA GGHPALYEEM VSVKLQVSNT GDRKGQEVVQ 

       970        980        990       1000       1010       1020 
VYVSFPPDFP ERVLRNFTKI ELEPSERREV QMTLSRKDLS YWSTREQNWV MPEGKFQIWV 

      1030 
GRSSRDLPLM GEY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS499602 Genomic DNA. Translation: EDP47625.1.

3D structure databases

ProteinModelPortalB0YD91.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAFUBT00009375; CADAFUBP00009206; CADAFUBG00009375.

Phylogenomic databases

HOGENOMHOG000031215.
OrthoDBEOG7HMS8F.
PhylomeDBB0YD91.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
ProtoNetSearch...

Entry information

Entry nameBGLE_ASPFC
AccessionPrimary (citable) accession number: B0YD91
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: April 8, 2008
Last modified: April 16, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries