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B0Y4D5

- XKS1_ASPFC

UniProt

B0Y4D5 - XKS1_ASPFC

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Protein

Probable D-xylulose kinase A

Gene

xkiA

Organism
Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway By similarity.By similarity

Catalytic activityi

ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei97 – 971SubstrateBy similarity
Binding sitei168 – 1681SubstrateBy similarity
Binding sitei284 – 2841SubstrateBy similarity
Binding sitei285 – 2851SubstrateBy similarity
Binding sitei366 – 3661ATPBy similarity
Binding sitei475 – 4751ATPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi471 – 4722ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. xylulokinase activity Source: UniProtKB-EC

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Xylose metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable D-xylulose kinase A (EC:2.7.1.17)
Short name:
Xylulokinase A
Gene namesi
Name:xkiA
ORF Names:AFUB_057400
OrganismiNeosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
Taxonomic identifieri451804 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000001699: Unassembled WGS sequence

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 573573Probable D-xylulose kinase APRO_0000393517Add
BLAST

Expressioni

Inductioni

By D-xylose, L-arabinose or L-arabitol.

Structurei

3D structure databases

ProteinModelPortaliB0Y4D5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FGGY kinase family.Curated

Phylogenomic databases

HOGENOMiHOG000174850.
OrthoDBiEOG7CRTZN.
PhylomeDBiB0Y4D5.

Family and domain databases

InterProiIPR018485. Carb_kinase_FGGY_C.
IPR018484. Carb_kinase_FGGY_N.
[Graphical view]
PfamiPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0Y4D5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTSQGPLYIG FDLSTQQLKG LVVNSELKVV HISKFDFDAD SHGFSIKKGV
60 70 80 90 100
LTNEAEHEVF APVALWLQAL DGVLNGLRKQ GLDFSRVKGI SGAGQQHGSV
110 120 130 140 150
YWGENAESLL KSLDSSKSLE EQLSGAFSHP FSPNWQDAST QKECDEFDAF
160 170 180 190 200
LGGPEQLAEA TGSKAHHRFT GPQILRMQRK YPEVYKKTAR ISLVSSFLAS
210 220 230 240 250
LLLGHIAPMD ISDVCGMNLW DIKKGAYNEK LLGLCAGPFG VEDLKRKLGA
260 270 280 290 300
VPEDGGLRLG KINRYFVERY GFSSDCEILP STGDNPATIL ALPLRPSDAM
310 320 330 340 350
VSLGTSTTFL MSTPNYKPDP ATHFFNHPTT PGLYMFMLCY KNGGLAREHV
360 370 380 390 400
RDAINEKSGS GASQSWESFD KIMLETPPMG QKTESGPMKM GLFFPRPEIV
410 420 430 440 450
PNVRSGQWRF TYDPASDALT ETEDGWNTPS DEARAIVESQ MLSLRLRSRG
460 470 480 490 500
LTQSPGDGLP PQPRRVYLVG GGSKNKAIAK VAGEILGGSD GVYKLDVGDN
510 520 530 540 550
ACALGAAYKA VWAIERKPGQ TFEDLIGQRW REEEFIEKIA DGYQKGVFEK
560 570
YGKAVEGFEK MEQQVLKQEA ARK
Length:573
Mass (Da):62,940
Last modified:April 8, 2008 - v1
Checksum:iFB1E317F57D2B829
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS499597 Genomic DNA. Translation: EDP51726.1.

Genome annotation databases

EnsemblFungiiCADAFUBT00005719; CADAFUBP00005619; CADAFUBG00005719.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS499597 Genomic DNA. Translation: EDP51726.1 .

3D structure databases

ProteinModelPortali B0Y4D5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADAFUBT00005719 ; CADAFUBP00005619 ; CADAFUBG00005719 .

Phylogenomic databases

HOGENOMi HOG000174850.
OrthoDBi EOG7CRTZN.
PhylomeDBi B0Y4D5.

Family and domain databases

InterProi IPR018485. Carb_kinase_FGGY_C.
IPR018484. Carb_kinase_FGGY_N.
[Graphical view ]
Pfami PF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CEA10 / CBS 144.89 / FGSC A1163.

Entry informationi

Entry nameiXKS1_ASPFC
AccessioniPrimary (citable) accession number: B0Y4D5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: April 8, 2008
Last modified: October 29, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3