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Protein

Transcription activator of gluconeogenesis acuK

Gene

acuK

Organism
Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi65 – 93Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST29

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Gluconeogenesis, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription activator of gluconeogenesis acuK
Gene namesi
Name:acuK
ORF Names:AN7468
OrganismiNeosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
Taxonomic identifieri451804 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000001699 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004064311 – 683Transcription activator of gluconeogenesis acuKAdd BLAST683

Proteomic databases

PRIDEiB0XVV1.

Family & Domainsi

Sequence similaritiesi

Belongs to the ERT1/acuK family.Curated
Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000162694.
OrthoDBiEOG092C2QST.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0XVV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTEVNGSAP ALAGDHGGVD QDTPDAGDRT EQAKHKTNGA TENAPKSANA
60 70 80 90 100
KDPSRPRRKK ARRACFACQR AHLTCGDERP CQRCIKRGLQ DACHDGVRKK
110 120 130 140 150
AKYLHDAPDG ALMPGVGGNF YNNAMRNNMP LSRNGTTTVN TTTQQNSGSN
160 170 180 190 200
YYPTPQSNSY NVYQDTPLTQ NSFPSQSPVS PTFNMKTTPT ARSNSLSSSV
210 220 230 240 250
NQQPPSTTVS GATQSQNPFA GPFFDPSDPA LFNFDLSSMN FENRYGALEF
260 270 280 290 300
GMLGHMATGA GDSPTDSATQ RGSIGRSGST QYSTTPLTGA PGFGESPGNQ
310 320 330 340 350
QPFLFGNDPL LNEWPNSQAP NQGHLNVSGV YPQGGMMHMA KSDAPHAFAI
360 370 380 390 400
ESGPASFSSP SATTSPHINS GHDESSLSNA AVNKSTGLTA NGQRPAITTP
410 420 430 440 450
SLKHQSLQFG VKRRQRNPST VYESVKEPYA YTNRFHNLTA FIQRRFSPQK
460 470 480 490 500
TLQIAKALAS IRPSFIATTK TLNRDDLIFM EKCFQRTLWE YEDFINACGT
510 520 530 540 550
PTIVCRRTGE IAAVGKEFSI LTGWKKDVLL GKEPNLNVNT GGSSAPGSGN
560 570 580 590 600
TSRGSFTPRS STLETATPGR PQPVFLAELL DDDSVVEFYE DFARLAFGDS
610 620 630 640 650
RGSVMTTCKL LKYKTKEDME LAQSDDNQRW NNHLRKGGIA GEAGMNQLGF
660 670 680
KDGKVECAYC WTVKRDVFDI PMLIVMNVFL PCI
Length:683
Mass (Da):74,093
Last modified:April 5, 2011 - v2
Checksum:iA63CD9A6D929413E
GO

Sequence cautioni

The sequence EDP54234 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS499595 Genomic DNA. Translation: EDP54234.1. Sequence problems.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS499595 Genomic DNA. Translation: EDP54234.1. Sequence problems.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB0XVV1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000162694.
OrthoDBiEOG092C2QST.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiACUK_ASPFC
AccessioniPrimary (citable) accession number: B0XVV1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 5, 2016
This is version 42 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.