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B0XTS1

- SCONB_ASPFC

UniProt

B0XTS1 - SCONB_ASPFC

Protein

Probable E3 ubiquitin ligase complex SCF subunit sconB

Gene

sconB

Organism
Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.By similarity

    Pathwayi

    GO - Biological processi

    1. protein ubiquitination Source: UniProtKB-UniPathway
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation, Ubl conjugation pathway

    Enzyme and pathway databases

    UniPathwayiUPA00143.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable E3 ubiquitin ligase complex SCF subunit sconB
    Alternative name(s):
    Sulfur controller B
    Sulfur metabolite repression control protein B
    Gene namesi
    Name:sconB
    ORF Names:AFUB_029730
    OrganismiNeosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
    Taxonomic identifieri451804 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000001699: Unassembled WGS sequence

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 696696Probable E3 ubiquitin ligase complex SCF subunit sconBPRO_0000397246Add
    BLAST

    Interactioni

    Subunit structurei

    Component of the SCF(sconB) E3 ubiquitin ligase complex.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliB0XTS1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini193 – 23947F-boxPROSITE-ProRule annotationAdd
    BLAST
    Repeati365 – 40238WD 1Add
    BLAST
    Repeati405 – 44440WD 2Add
    BLAST
    Repeati446 – 48237WD 3Add
    BLAST
    Repeati484 – 52542WD 4Add
    BLAST
    Repeati579 – 62244WD 5Add
    BLAST
    Repeati623 – 66240WD 6Add
    BLAST
    Repeati665 – 69632WD 7Add
    BLAST

    Sequence similaritiesi

    Contains 1 F-box domain.PROSITE-ProRule annotation
    Contains 7 WD repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, WD repeat

    Phylogenomic databases

    HOGENOMiHOG000166480.
    OrthoDBiEOG7C5MHX.
    PhylomeDBiB0XTS1.

    Family and domain databases

    Gene3Di2.130.10.10. 3 hits.
    InterProiIPR001810. F-box_dom.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF12937. F-box-like. 1 hit.
    PF00400. WD40. 7 hits.
    [Graphical view]
    PRINTSiPR00320. GPROTEINBRPT.
    SMARTiSM00256. FBOX. 1 hit.
    SM00320. WD40. 7 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 2 hits.
    SSF81383. SSF81383. 2 hits.
    PROSITEiPS50181. FBOX. 1 hit.
    PS00678. WD_REPEATS_1. 4 hits.
    PS50082. WD_REPEATS_2. 7 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0XTS1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDAHELSFRD GHGSSTSTMK DGCASAEKPH YLPGDSSFTS VFGPSETVED    50
    VETEPGSTQD KPHSFNTQKP IRENLAGKNV APFLARHIPE QYAPLGSQGG 100
    QPVEISSANS KYCYRHRPDL KCRRQADEPT MDKLQRELET LPQSDQQGIA 150
    HAWSIFSAAP AKHRKLILQG IMAQCCFPQL SFISATVRDL IRIDFLTALP 200
    PEISFKILCY LDTTSLCKAA QVSRRWRALA DDDVVWHRMC EQHIHRKCKK 250
    CGWGLPLLDR KRLRESKREI ERRAATWDVS KQPAGIEGSS ATIETAAAGS 300
    KRKPESGKED TAMVKRQCTS IVSQSEQNED YFKTRYRPWK EVYKDRFKVG 350
    TNWKYGRCST RVFKGHSNGI MCLQFEDNIL ATGSYDATIK IWDTETGEEL 400
    RTLKGHQSGI RCLQFDDTKL ISGSMDHTLK VWNWRTGECI STYSGHRGGV 450
    VGLHFDATIL ASGSVDKTVK IWNFEDKSTC LLRGHTDWVN AVRVDSASRT 500
    VFSASDDCTV KLWDLDTKSC IRTFHGHVGQ VQQVVPLPRE FEFEDHDVEC 550
    ENDNVSVTSG DSPAASPQAL PGFDGQTSDT PSSAFGPAFD DGRPSPPRYI 600
    VTSALDSTIR LWETSSGRCL RTFFGHLEGV WALAADTLRI VSGAEDRMVK 650
    IWDPRTGKCE RTFTGHSGPV TCIGLGDSRF ATGSEDCEVR MYSFQT 696
    Length:696
    Mass (Da):77,712
    Last modified:April 8, 2008 - v1
    Checksum:i0377045046AA18C7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS499595 Genomic DNA. Translation: EDP54913.1.

    Genome annotation databases

    EnsemblFungiiCADAFUBT00002968; CADAFUBP00002912; CADAFUBG00002968.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS499595 Genomic DNA. Translation: EDP54913.1 .

    3D structure databases

    ProteinModelPortali B0XTS1.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADAFUBT00002968 ; CADAFUBP00002912 ; CADAFUBG00002968 .

    Phylogenomic databases

    HOGENOMi HOG000166480.
    OrthoDBi EOG7C5MHX.
    PhylomeDBi B0XTS1.

    Enzyme and pathway databases

    UniPathwayi UPA00143 .

    Family and domain databases

    Gene3Di 2.130.10.10. 3 hits.
    InterProi IPR001810. F-box_dom.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF12937. F-box-like. 1 hit.
    PF00400. WD40. 7 hits.
    [Graphical view ]
    PRINTSi PR00320. GPROTEINBRPT.
    SMARTi SM00256. FBOX. 1 hit.
    SM00320. WD40. 7 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 2 hits.
    SSF81383. SSF81383. 2 hits.
    PROSITEi PS50181. FBOX. 1 hit.
    PS00678. WD_REPEATS_1. 4 hits.
    PS50082. WD_REPEATS_2. 7 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CEA10 / CBS 144.89 / FGSC A1163.

    Entry informationi

    Entry nameiSCONB_ASPFC
    AccessioniPrimary (citable) accession number: B0XTS1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 10, 2010
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3