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B0XTS1 (SCONB_ASPFC) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable E3 ubiquitin ligase complex SCF subunit sconB
Alternative name(s):
Sulfur controller B
Sulfur metabolite repression control protein B
Gene names
Name:sconB
ORF Names:AFUB_029730
OrganismNeosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus) [Complete proteome]
Taxonomic identifier451804 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length696 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor By similarity.

Pathway

Protein modification; protein ubiquitination.

Subunit structure

Component of the SCF(sconB) E3 ubiquitin ligase complex By similarity.

Sequence similarities

Belongs to the WD repeat MET30/SCONB/SCON-2 family.

Contains 1 F-box domain.

Contains 7 WD repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 696696Probable E3 ubiquitin ligase complex SCF subunit sconB
PRO_0000397246

Regions

Domain193 – 23947F-box
Repeat365 – 40238WD 1
Repeat405 – 44440WD 2
Repeat446 – 48237WD 3
Repeat484 – 52542WD 4
Repeat579 – 62244WD 5
Repeat623 – 66240WD 6
Repeat665 – 69632WD 7

Sequences

Sequence LengthMass (Da)Tools
B0XTS1 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 0377045046AA18C7

FASTA69677,712
        10         20         30         40         50         60 
MDAHELSFRD GHGSSTSTMK DGCASAEKPH YLPGDSSFTS VFGPSETVED VETEPGSTQD 

        70         80         90        100        110        120 
KPHSFNTQKP IRENLAGKNV APFLARHIPE QYAPLGSQGG QPVEISSANS KYCYRHRPDL 

       130        140        150        160        170        180 
KCRRQADEPT MDKLQRELET LPQSDQQGIA HAWSIFSAAP AKHRKLILQG IMAQCCFPQL 

       190        200        210        220        230        240 
SFISATVRDL IRIDFLTALP PEISFKILCY LDTTSLCKAA QVSRRWRALA DDDVVWHRMC 

       250        260        270        280        290        300 
EQHIHRKCKK CGWGLPLLDR KRLRESKREI ERRAATWDVS KQPAGIEGSS ATIETAAAGS 

       310        320        330        340        350        360 
KRKPESGKED TAMVKRQCTS IVSQSEQNED YFKTRYRPWK EVYKDRFKVG TNWKYGRCST 

       370        380        390        400        410        420 
RVFKGHSNGI MCLQFEDNIL ATGSYDATIK IWDTETGEEL RTLKGHQSGI RCLQFDDTKL 

       430        440        450        460        470        480 
ISGSMDHTLK VWNWRTGECI STYSGHRGGV VGLHFDATIL ASGSVDKTVK IWNFEDKSTC 

       490        500        510        520        530        540 
LLRGHTDWVN AVRVDSASRT VFSASDDCTV KLWDLDTKSC IRTFHGHVGQ VQQVVPLPRE 

       550        560        570        580        590        600 
FEFEDHDVEC ENDNVSVTSG DSPAASPQAL PGFDGQTSDT PSSAFGPAFD DGRPSPPRYI 

       610        620        630        640        650        660 
VTSALDSTIR LWETSSGRCL RTFFGHLEGV WALAADTLRI VSGAEDRMVK IWDPRTGKCE 

       670        680        690 
RTFTGHSGPV TCIGLGDSRF ATGSEDCEVR MYSFQT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS499595 Genomic DNA. Translation: EDP54913.1.

3D structure databases

ProteinModelPortalB0XTS1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAFUBT00002968; CADAFUBP00002912; CADAFUBG00002968.

Phylogenomic databases

HOGENOMHOG000166480.
OrthoDBEOG7C5MHX.
PhylomeDBB0XTS1.

Enzyme and pathway databases

UniPathwayUPA00143.

Family and domain databases

Gene3D2.130.10.10. 3 hits.
InterProIPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamPF12937. F-box-like. 1 hit.
PF00400. WD40. 7 hits.
[Graphical view]
PRINTSPR00320. GPROTEINBRPT.
SMARTSM00256. FBOX. 1 hit.
SM00320. WD40. 7 hits.
[Graphical view]
SUPFAMSSF50978. SSF50978. 2 hits.
SSF81383. SSF81383. 2 hits.
PROSITEPS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 4 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSCONB_ASPFC
AccessionPrimary (citable) accession number: B0XTS1
Entry history
Integrated into UniProtKB/Swiss-Prot: August 10, 2010
Last sequence update: April 8, 2008
Last modified: June 11, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways