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B0XPR3

- GANA_ASPFC

UniProt

B0XPR3 - GANA_ASPFC

Protein

Probable arabinogalactan endo-beta-1,4-galactanase A

Gene

galA

Organism
Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 2 (15 Jun 2010)
      Previous versions | rss
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    Functioni

    Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin.By similarity

    Catalytic activityi

    The enzyme specifically hydrolyzes (1->4)-beta-D-galactosidic linkages in type I arabinogalactans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei157 – 1571Proton donorBy similarity
    Active sitei268 – 2681NucleophileBy similarity

    GO - Molecular functioni

    1. arabinogalactan endo-1,4-beta-galactosidase activity Source: UniProtKB
    2. glucosidase activity Source: InterPro

    GO - Biological processi

    1. pectin catabolic process Source: UniProtKB

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable arabinogalactan endo-beta-1,4-galactanase A (EC:3.2.1.89)
    Alternative name(s):
    Endo-1,4-beta-galactanase A
    Short name:
    Galactanase A
    Gene namesi
    Name:galA
    ORF Names:AFUB_007290
    OrganismiNeosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
    Taxonomic identifieri451804 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000001699: Unassembled WGS sequence

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2121Sequence AnalysisAdd
    BLAST
    Chaini22 – 356335Probable arabinogalactan endo-beta-1,4-galactanase APRO_0000394944Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi133 – 1331N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Structurei

    3D structure databases

    ProteinModelPortaliB0XPR3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 53 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    HOGENOMiHOG000217077.
    OrthoDBiEOG7CG78S.
    PhylomeDBiB0XPR3.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR011683. Glyco_hydro_53.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF07745. Glyco_hydro_53. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    B0XPR3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLGKTVLLPL LVLLCHSLAS ASLVYRGADI SSLLIEEKAG IEYKNVNGQT    50
    QPLENILKAN GVNSVRQRVW VNPSDGSYNL DYNVKLAKRV KAAGMSVYLD 100
    LHFSDTWADP SHQTTPRGWS TNDIGTLTWQ VYNYTMEVCN TFASNGIDVS 150
    IVAIGNEIRN GLLWPLGKPD NYANIANILH SAAFGVKDST LSPKPKIMIH 200
    LDNGWDWSAQ KFFYDRVLSS GANLVKSDFD LIGVSYYPFY NPSATLSALT 250
    TSLKNLRSTY GKDVLVVETD WPVLCPNPAY AFPSDLKDIP FSVAGQTTFV 300
    QRVANIVAQT PGGIGLYYWE PAWVQNAALG SSCADNLMVD WSTRQARTSL 350
    SVFATI 356
    Length:356
    Mass (Da):39,132
    Last modified:June 15, 2010 - v2
    Checksum:iC36E62DABE9805D5
    GO

    Sequence cautioni

    The sequence EDP56027.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS499594 Genomic DNA. Translation: EDP56027.1. Different initiation.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS499594 Genomic DNA. Translation: EDP56027.1 . Different initiation.

    3D structure databases

    ProteinModelPortali B0XPR3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000217077.
    OrthoDBi EOG7CG78S.
    PhylomeDBi B0XPR3.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR011683. Glyco_hydro_53.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF07745. Glyco_hydro_53. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CEA10 / CBS 144.89 / FGSC A1163.

    Entry informationi

    Entry nameiGANA_ASPFC
    AccessioniPrimary (citable) accession number: B0XPR3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 15, 2010
    Last sequence update: June 15, 2010
    Last modified: October 1, 2014
    This is version 35 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3