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B0XAP5

- B0XAP5_CULQU

UniProt

B0XAP5 - B0XAP5_CULQU

Protein
Submitted name:

Histone-lysine N-methyltransferase SETDB1

Gene

CpipJ_CPIJ016652

Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. histone-lysine N-methyltransferase activity Source: InterPro
    3. zinc ion binding Source: InterPro

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionineSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Histone-lysine N-methyltransferase SETDB1Imported
    Gene namesi
    ORF Names:CpipJ_CPIJ016652Imported
    OrganismiCulex quinquefasciatus (Southern house mosquito) (Culex pungens)Imported
    Taxonomic identifieri7176 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeCuliciniCulexCulex
    ProteomesiUP000002320: Partially assembled WGS sequence

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. chromosome Source: UniProtKB-KW
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    ChromosomeSAAS annotation, NucleusUniRule annotationSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi7176.CPIJ016652-PA.

    Structurei

    3D structure databases

    ProteinModelPortaliB0XAP5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation
    Contains 1 post-SET domain.
    Contains 1 pre-SET domain.UniRule annotation
    Contains SET domain.SAAS annotation
    Contains pre-SET domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG2940.
    HOGENOMiHOG000047815.
    KOiK11421.
    OMAiCKCKKNC.
    PhylomeDBiB0XAP5.

    Family and domain databases

    Gene3Di3.30.890.10. 1 hit.
    InterProiIPR016177. DNA-bd_dom.
    IPR001739. Methyl_CpG_DNA-bd.
    IPR003616. Post-SET_dom.
    IPR007728. Pre-SET_dom.
    IPR001214. SET_dom.
    IPR002999. Tudor.
    [Graphical view]
    PfamiPF01429. MBD. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view]
    SMARTiSM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    SM00333. TUDOR. 2 hits.
    [Graphical view]
    SUPFAMiSSF54171. SSF54171. 1 hit.
    PROSITEiPS50982. MBD. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0XAP5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPRKNELVEI SDSSEEEEDA DTKSETEKPL PEDIVALIDT ELNDILTSTF     50
    EKINLEQQIE WTEQIMKQKI AYNTKISDEI NNELNELQRK VDRIHLQLYS 100
    KSRPKYQDLP PCNIFHEVDL LGKAHITTQS QPAATPTNRQ YSPQKQHQSA 150
    TPSQQAPAAT AAAAKEEFVR PAVIVGQFYF AVKHKLLSNW AECQVVEAVN 200
    VADKALYKVN FLFNQGAGSA PIKVVPAKYL AYRHSFNVKL PLGTRVIARF 250
    DAGSSTAPPG KANQQMQAKT NAFYPGIIAE SFGKYNRHRY LIFFDDGYAQ 300
    YVSHGDVRVV CEESKEVWAD IHPHSQEFIK AYLQNYRSQR PMVQVKVGQR 350
    IITEWKGKWI YAKVVDIDAS LVQLFFPDDN RHEWIYRGST RLGPLYQEKA 400
    LSMTKANNKF SKFQKRNEPS IEYITLDDDD DDQNKQSDAK KAQPSQDLQQ 450
    YNKTLQQTML DNAAANRSVA KKSTFNRPVP AAPAAPQQPS AVFMNSSTIY 500
    CEDDRPKGKI VYYTAKKHLP PLKYKQHQCS PSCLFKITHN LKSYSPLAKP 550
    LLSGWERQLC KMKYKKVFVV YRGPCGRRLR NMYELHMYLR MTNATLNVEN 600
    FDFDPVIHCL AEYVIENHIY HNPDLSDGKE YMAVPCVNYF DDTKPPPCIY 650
    STERIPTEGV NLNLDEDFMC GCDCEDDCID KSRCQCWQLT VAGAKFTNQN 700
    TPIDNIGYVY KRLQEPVLTG IYECNSRCKC KTNCLNRVVQ HPLQTKLQVF 750
    KTSNRGWGIR CLNDVSKGSF ICIYSGHLLT EEAGNNICQS NSNKAGDEYF 800
    ADLDYIETVE QLKEGYEADV VESESENDSD GPDYDAKRDS DASDDDFTSS 850
    INPSDAAVKT RAQLRKDAKK SDKKSQKKKE DPKQDSDDAE REMISVMPNT 900
    DMVKGDVASP SIKYRSVRKL FGKHEQIYIM DAKKSGNLGR YFNHSCNPNL 950
    FVQNVFVDTH DLRFPWVAFF ALSNIRAGSE LTWNYNYDVG SVPGKVLYCQ 1000
    CGAENCRQRL L 1011
    Length:1,011
    Mass (Da):115,310
    Last modified:April 8, 2008 - v1
    Checksum:i4294AE60F64C05E4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS232592 Genomic DNA. Translation: EDS43834.1.
    RefSeqiXP_001866717.1. XM_001866682.1.

    Genome annotation databases

    GeneIDi6050045.
    KEGGicqu:CpipJ_CPIJ016652.
    VectorBaseiCPIJ016652. Culex quinquefasciatus.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS232592 Genomic DNA. Translation: EDS43834.1 .
    RefSeqi XP_001866717.1. XM_001866682.1.

    3D structure databases

    ProteinModelPortali B0XAP5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7176.CPIJ016652-PA.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 6050045.
    KEGGi cqu:CpipJ_CPIJ016652.
    VectorBasei CPIJ016652. Culex quinquefasciatus.

    Phylogenomic databases

    eggNOGi COG2940.
    HOGENOMi HOG000047815.
    KOi K11421.
    OMAi CKCKKNC.
    PhylomeDBi B0XAP5.

    Family and domain databases

    Gene3Di 3.30.890.10. 1 hit.
    InterProi IPR016177. DNA-bd_dom.
    IPR001739. Methyl_CpG_DNA-bd.
    IPR003616. Post-SET_dom.
    IPR007728. Pre-SET_dom.
    IPR001214. SET_dom.
    IPR002999. Tudor.
    [Graphical view ]
    Pfami PF01429. MBD. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view ]
    SMARTi SM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    SM00333. TUDOR. 2 hits.
    [Graphical view ]
    SUPFAMi SSF54171. SSF54171. 1 hit.
    PROSITEi PS50982. MBD. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JHBImported.

    Entry informationi

    Entry nameiB0XAP5_CULQU
    AccessioniPrimary (citable) accession number: B0XAP5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3