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B0XAP5

- B0XAP5_CULQU

UniProt

B0XAP5 - B0XAP5_CULQU

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Protein
Submitted name:

Histone-lysine N-methyltransferase SETDB1

Gene
CpipJ_CPIJ016652
Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].UniRule annotationSAAS annotations

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. histone-lysine N-methyltransferase activity Source: InterPro
  3. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Histone-lysine N-methyltransferase SETDB1Imported
Gene namesi
ORF Names:CpipJ_CPIJ016652Imported
OrganismiCulex quinquefasciatus (Southern house mosquito) (Culex pungens)
Taxonomic identifieri7176 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeCuliciniCulexCulex
ProteomesiUP000002320: Partially assembled WGS sequence

Subcellular locationi

Nucleus By similarity UniRule annotation

GO - Cellular componenti

  1. chromosome Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

ChromosomeSAAS annotations, NucleusUniRule annotationSAAS annotations

Interactioni

Protein-protein interaction databases

STRINGi7176.CPIJ016652-PA.

Structurei

3D structure databases

ProteinModelPortaliB0XAP5.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.
Contains 1 post-SET domain.UniRule annotation
Contains 1 pre-SET domain.UniRule annotation
Contains SET domain.SAAS annotations
Contains pre-SET domain.SAAS annotations

Phylogenomic databases

eggNOGiCOG2940.
HOGENOMiHOG000047815.
KOiK11421.
OMAiCKCKKNC.
PhylomeDBiB0XAP5.

Family and domain databases

Gene3Di3.30.890.10. 1 hit.
InterProiIPR016177. DNA-bd_dom.
IPR001739. Methyl_CpG_DNA-bd.
IPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
IPR002999. Tudor.
[Graphical view]
PfamiPF01429. MBD. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00333. TUDOR. 2 hits.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS50982. MBD. 1 hit.
PS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0XAP5-1 [UniParc]FASTAAdd to Basket

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MPRKNELVEI SDSSEEEEDA DTKSETEKPL PEDIVALIDT ELNDILTSTF     50
EKINLEQQIE WTEQIMKQKI AYNTKISDEI NNELNELQRK VDRIHLQLYS 100
KSRPKYQDLP PCNIFHEVDL LGKAHITTQS QPAATPTNRQ YSPQKQHQSA 150
TPSQQAPAAT AAAAKEEFVR PAVIVGQFYF AVKHKLLSNW AECQVVEAVN 200
VADKALYKVN FLFNQGAGSA PIKVVPAKYL AYRHSFNVKL PLGTRVIARF 250
DAGSSTAPPG KANQQMQAKT NAFYPGIIAE SFGKYNRHRY LIFFDDGYAQ 300
YVSHGDVRVV CEESKEVWAD IHPHSQEFIK AYLQNYRSQR PMVQVKVGQR 350
IITEWKGKWI YAKVVDIDAS LVQLFFPDDN RHEWIYRGST RLGPLYQEKA 400
LSMTKANNKF SKFQKRNEPS IEYITLDDDD DDQNKQSDAK KAQPSQDLQQ 450
YNKTLQQTML DNAAANRSVA KKSTFNRPVP AAPAAPQQPS AVFMNSSTIY 500
CEDDRPKGKI VYYTAKKHLP PLKYKQHQCS PSCLFKITHN LKSYSPLAKP 550
LLSGWERQLC KMKYKKVFVV YRGPCGRRLR NMYELHMYLR MTNATLNVEN 600
FDFDPVIHCL AEYVIENHIY HNPDLSDGKE YMAVPCVNYF DDTKPPPCIY 650
STERIPTEGV NLNLDEDFMC GCDCEDDCID KSRCQCWQLT VAGAKFTNQN 700
TPIDNIGYVY KRLQEPVLTG IYECNSRCKC KTNCLNRVVQ HPLQTKLQVF 750
KTSNRGWGIR CLNDVSKGSF ICIYSGHLLT EEAGNNICQS NSNKAGDEYF 800
ADLDYIETVE QLKEGYEADV VESESENDSD GPDYDAKRDS DASDDDFTSS 850
INPSDAAVKT RAQLRKDAKK SDKKSQKKKE DPKQDSDDAE REMISVMPNT 900
DMVKGDVASP SIKYRSVRKL FGKHEQIYIM DAKKSGNLGR YFNHSCNPNL 950
FVQNVFVDTH DLRFPWVAFF ALSNIRAGSE LTWNYNYDVG SVPGKVLYCQ 1000
CGAENCRQRL L 1011
Length:1,011
Mass (Da):115,310
Last modified:April 8, 2008 - v1
Checksum:i4294AE60F64C05E4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS232592 Genomic DNA. Translation: EDS43834.1.
RefSeqiXP_001866717.1. XM_001866682.1.

Genome annotation databases

GeneIDi6050045.
KEGGicqu:CpipJ_CPIJ016652.
VectorBaseiCPIJ016652. Culex quinquefasciatus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS232592 Genomic DNA. Translation: EDS43834.1 .
RefSeqi XP_001866717.1. XM_001866682.1.

3D structure databases

ProteinModelPortali B0XAP5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7176.CPIJ016652-PA.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 6050045.
KEGGi cqu:CpipJ_CPIJ016652.
VectorBasei CPIJ016652. Culex quinquefasciatus.

Phylogenomic databases

eggNOGi COG2940.
HOGENOMi HOG000047815.
KOi K11421.
OMAi CKCKKNC.
PhylomeDBi B0XAP5.

Family and domain databases

Gene3Di 3.30.890.10. 1 hit.
InterProi IPR016177. DNA-bd_dom.
IPR001739. Methyl_CpG_DNA-bd.
IPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
IPR002999. Tudor.
[Graphical view ]
Pfami PF01429. MBD. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00333. TUDOR. 2 hits.
[Graphical view ]
SUPFAMi SSF54171. SSF54171. 1 hit.
PROSITEi PS50982. MBD. 1 hit.
PS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JHB.

Entry informationi

Entry nameiB0XAP5_CULQU
AccessioniPrimary (citable) accession number: B0XAP5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: April 16, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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