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Protein

Histone-lysine N-methyltransferase

Gene

CpipJ_CPIJ016652

Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
ORF Names:CpipJ_CPIJ016652Imported
OrganismiCulex quinquefasciatus (Southern house mosquito) (Culex pungens)Imported
Taxonomic identifieri7176 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeCuliciniCulexCulex
ProteomesiUP000002320 Componenti: Partially assembled WGS sequence

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

ChromosomeSAAS annotation, NucleusUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7176.CPIJ802311-PA.

Structurei

3D structure databases

ProteinModelPortaliB0XAP5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation
Contains 1 pre-SET domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG2940.
HOGENOMiHOG000047815.
InParanoidiB0XAP5.
KOiK11421.
OMAiWSKTILQ.
PhylomeDBiB0XAP5.

Family and domain databases

Gene3Di3.30.890.10. 1 hit.
InterProiIPR016177. DNA-bd_dom.
IPR001739. Methyl_CpG_DNA-bd.
IPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
IPR002999. Tudor.
[Graphical view]
PfamiPF01429. MBD. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00333. TUDOR. 2 hits.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS50982. MBD. 1 hit.
PS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0XAP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRKNELVEI SDSSEEEEDA DTKSETEKPL PEDIVALIDT ELNDILTSTF
60 70 80 90 100
EKINLEQQIE WTEQIMKQKI AYNTKISDEI NNELNELQRK VDRIHLQLYS
110 120 130 140 150
KSRPKYQDLP PCNIFHEVDL LGKAHITTQS QPAATPTNRQ YSPQKQHQSA
160 170 180 190 200
TPSQQAPAAT AAAAKEEFVR PAVIVGQFYF AVKHKLLSNW AECQVVEAVN
210 220 230 240 250
VADKALYKVN FLFNQGAGSA PIKVVPAKYL AYRHSFNVKL PLGTRVIARF
260 270 280 290 300
DAGSSTAPPG KANQQMQAKT NAFYPGIIAE SFGKYNRHRY LIFFDDGYAQ
310 320 330 340 350
YVSHGDVRVV CEESKEVWAD IHPHSQEFIK AYLQNYRSQR PMVQVKVGQR
360 370 380 390 400
IITEWKGKWI YAKVVDIDAS LVQLFFPDDN RHEWIYRGST RLGPLYQEKA
410 420 430 440 450
LSMTKANNKF SKFQKRNEPS IEYITLDDDD DDQNKQSDAK KAQPSQDLQQ
460 470 480 490 500
YNKTLQQTML DNAAANRSVA KKSTFNRPVP AAPAAPQQPS AVFMNSSTIY
510 520 530 540 550
CEDDRPKGKI VYYTAKKHLP PLKYKQHQCS PSCLFKITHN LKSYSPLAKP
560 570 580 590 600
LLSGWERQLC KMKYKKVFVV YRGPCGRRLR NMYELHMYLR MTNATLNVEN
610 620 630 640 650
FDFDPVIHCL AEYVIENHIY HNPDLSDGKE YMAVPCVNYF DDTKPPPCIY
660 670 680 690 700
STERIPTEGV NLNLDEDFMC GCDCEDDCID KSRCQCWQLT VAGAKFTNQN
710 720 730 740 750
TPIDNIGYVY KRLQEPVLTG IYECNSRCKC KTNCLNRVVQ HPLQTKLQVF
760 770 780 790 800
KTSNRGWGIR CLNDVSKGSF ICIYSGHLLT EEAGNNICQS NSNKAGDEYF
810 820 830 840 850
ADLDYIETVE QLKEGYEADV VESESENDSD GPDYDAKRDS DASDDDFTSS
860 870 880 890 900
INPSDAAVKT RAQLRKDAKK SDKKSQKKKE DPKQDSDDAE REMISVMPNT
910 920 930 940 950
DMVKGDVASP SIKYRSVRKL FGKHEQIYIM DAKKSGNLGR YFNHSCNPNL
960 970 980 990 1000
FVQNVFVDTH DLRFPWVAFF ALSNIRAGSE LTWNYNYDVG SVPGKVLYCQ
1010
CGAENCRQRL L
Length:1,011
Mass (Da):115,310
Last modified:April 8, 2008 - v1
Checksum:i4294AE60F64C05E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS232592 Genomic DNA. Translation: EDS43834.1.
RefSeqiXP_001866717.1. XM_001866682.1.

Genome annotation databases

GeneIDi6050045.
KEGGicqu:CpipJ_CPIJ016652.
VectorBaseiCPIJ016652. Culex quinquefasciatus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS232592 Genomic DNA. Translation: EDS43834.1.
RefSeqiXP_001866717.1. XM_001866682.1.

3D structure databases

ProteinModelPortaliB0XAP5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7176.CPIJ802311-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6050045.
KEGGicqu:CpipJ_CPIJ016652.
VectorBaseiCPIJ016652. Culex quinquefasciatus.

Phylogenomic databases

eggNOGiCOG2940.
HOGENOMiHOG000047815.
InParanoidiB0XAP5.
KOiK11421.
OMAiWSKTILQ.
PhylomeDBiB0XAP5.

Family and domain databases

Gene3Di3.30.890.10. 1 hit.
InterProiIPR016177. DNA-bd_dom.
IPR001739. Methyl_CpG_DNA-bd.
IPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
IPR002999. Tudor.
[Graphical view]
PfamiPF01429. MBD. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00333. TUDOR. 2 hits.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS50982. MBD. 1 hit.
PS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JHBImported.

Entry informationi

Entry nameiB0XAP5_CULQU
AccessioniPrimary (citable) accession number: B0XAP5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: June 24, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.