Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B0X9V1 (FBSP1_CULQU) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
F-box/SPRY domain-containing protein 1
Gene names
Name:Fsn
ORF Names:CPIJ016123
OrganismCulex quinquefasciatus (Southern house mosquito) (Culex pungens) [Complete proteome]
Taxonomic identifier7176 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeCuliciniCulexCulex

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Required in the presynaptic motoneuron to down-regulate the levels of wnd and restrain synaptic terminal growth at the neuromuscular junction (NMJ) By similarity. UniProtKB Q9V6L9

Pathway

Protein modification; protein ubiquitination. UniProtKB Q9V6L9

Subunit structure

Component of an E3 ubiquitin ligase complex composed of hiw and Fsn By similarity. UniProtKB Q9V6L9

Subcellular location

Cell junctionsynapse By similarity UniProtKB Q9V6L9.

Sequence similarities

Belongs to the FBXO45/Fsn family.

Contains 1 B30.2/SPRY domain.

Contains 1 F-box domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 258258F-box/SPRY domain-containing protein 1
PRO_0000383309

Regions

Domain6 – 5449F-box
Domain64 – 256193B30.2/SPRY

Sequences

Sequence LengthMass (Da)Tools
B0X9V1 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 6C48CF803C93BF6D

FASTA25829,186
        10         20         30         40         50         60 
MDDDLTEYAP DIPDNVLELI FSYLKLQDLR NCALVCKSWH RFLSDENNEV WRAQCMQKLS 

        70         80         90        100        110        120 
PDAFKTDLLS VVPTYKAKLR AFFHAWNPYD CSRHVYIKPN GFTLHRNPVA QSTDGSRGKI 

       130        140        150        160        170        180 
GFQHGRHAWE VRWEGPLGTV AVVGIATKDA AIQCHGYYAL LGADDQSWGW NLVDNLLLHN 

       190        200        210        220        230        240 
GDAHGIYPLL NNAPKYKVGE RIRVILDCDD NTLSFEKNYE FLGVAFTDLP DKVFYPTVAA 

       250 
VYGNTEISMV YLGPPLDG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS232551 Genomic DNA. Translation: EDS43303.1.
RefSeqXP_001866423.1. XM_001866388.1.

3D structure databases

ProteinModelPortalB0X9V1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7176.CPIJ016123-PA.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaCPIJ016123-RA; CPIJ016123-PA; CPIJ016123.
GeneID6049704.
KEGGcqu:CpipJ_CPIJ016123.
VectorBaseCPIJ016123. Culex quinquefasciatus.

Phylogenomic databases

eggNOGNOG263387.
HOGENOMHOG000230524.
KOK10319.
OMAILDCDDN.
OrthoDBEOG7QZGBV.
PhylomeDBB0X9V1.

Enzyme and pathway databases

UniPathwayUPA00143.

Family and domain databases

InterProIPR001870. B30.2/SPRY.
IPR008985. ConA-like_lec_gl_sf.
IPR001810. F-box_dom.
IPR018355. SPla/RYanodine_receptor_subgr.
IPR003877. SPRY_rcpt.
[Graphical view]
PfamPF00622. SPRY. 1 hit.
[Graphical view]
SMARTSM00256. FBOX. 1 hit.
SM00449. SPRY. 1 hit.
[Graphical view]
SUPFAMSSF49899. SSF49899. 1 hit.
SSF81383. SSF81383. 1 hit.
PROSITEPS50188. B302_SPRY. 1 hit.
PS50181. FBOX. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFBSP1_CULQU
AccessionPrimary (citable) accession number: B0X9V1
Entry history
Integrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: April 8, 2008
Last modified: March 19, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways