B0X1P4 (B0X1P4_CULQU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histone deacetylase PIRNR PIRNR037913
EC=3.5.1.98 PIRNR PIRNR037913

Gene names

ORF Names:

CpipJ_CPIJ013384 EMBL EDS38772.1

Organism

Culex quinquefasciatus (Southern house mosquito) (Culex pungens) [Complete proteome]

Taxonomic identifier

7176 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Culicoidea › Culicidae › Culicinae › Culicini › Culex › Culex › Culex pipiens complex

Protein attributes

Sequence length	431 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone. PIRNR PIRNR037913
Subcellular location	Nucleus By similarity PIRNR PIRNR037913.
Sequence similarities	Belongs to the histone deacetylase family. HD Type 1 subfamily. PIRNR PIRNR037913

Ontologies

Keywords
Biological process	Transcription Transcription regulation PIRNR PIRNR037913
Cellular component	Nucleus PIRNR PIRNR037913
Molecular function	Chromatin regulator PIRNR PIRNR037913 Hydrolase PIRNR PIRNR037913 SAAS SAAS000286
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	histone H3 deacetylation Inferred from electronic annotation. Source: GOC histone H4 deacetylation Inferred from electronic annotation. Source: GOC regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	NAD-dependent histone deacetylase activity (H3-K14 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H3-K18 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H3-K9 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H4-K16 specific) Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0X1P4 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: F6FBB3424DC74735	FASTA	431	49,048
	10 20 30 40 50 60 MGTKKVSYFF NPDVGNFHYG PGHPMKPHRL SVIHHLVMNY GLHKKMQIYR PYKASAHDMC 70 80 90 100 110 120 RFHSDEYIDF LQRVTPQNIQ GYTKCLSTFN VGDDCPVFDG LFEFCAMYTG ASLEGAQKLN 130 140 150 160 170 180 HNHSDICINW SGGLHHAKKF EASGFCYVND IVIGILELLK YHPRVLYIDI DVHHGDGVQE 190 200 210 220 230 240 AFYLTDRVMT VSFHKYGNYF FPGTGDMYEI GAESGRYYSV NVPLKEGIDD QSYVATFKPV 250 260 270 280 290 300 ITYVMDFYKP TAIVLQCGAD SLAGDRLGCF SLSTKGHGEC VKFVKDLNVP TLVVGGGGYT 310 320 330 340 350 360 LRNVARCWTY ETSLLIDETI SNELPMNDYL EFFAPDFTLH PDIPSRQDNA NSKQYLEAIT 370 380 390 400 410 420 KHVYDNLKMC QHAPSVQMFH IPEDALPEEV KVKEEPNPEA RMTQEEEDKH VEPKNEFFDG 430 ENDNDKSEND P

References

[1]

"Annotation of Culex pipiens quinquefasciatus." The Broad Institute Genome Sequencing Platform Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D., Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P., Antoine C.H. , Arensburger P., Bidwell S.L., Crawford M., Camaro F., Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D., Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J., Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E., Fraser-Liggett C.M., Strausberg R., Galagan J., Birren B., Collins F.H. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JHB.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS232266 Genomic DNA. Translation: EDS38772.1.
RefSeq	XP_001863566.1. XM_001863531.1.
UniGene	Cpi.8957.
3D structure databases
ProteinModelPortal	B0X1P4.
ModBase	Search...
Protein-protein interaction databases
STRING	7176.CPIJ013384-PA. B0X1P4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	CPIJ013384-RA; CPIJ013384-PA; CPIJ013384.
GeneID	6046349.
KEGG	cqu:CpipJ_CPIJ013384.
VectorBase	CPIJ013384. Culex quinquefasciatus.
Phylogenomic databases
eggNOG	COG0123.
HOGENOM	HOG000225180.
KO	K11404.
OMA	NFHYGPG.
OrthoDB	EOG4TB2SH.
PhylomeDB	B0X1P4.
Family and domain databases
Gene3D	3.40.800.20. 1 hit.
InterPro	IPR000286. His_deacetylse. IPR003084. His_deacetylse_1. IPR023801. His_deacetylse_dom. [Graphical view]
PANTHER	PTHR10625. PTHR10625. 1 hit.
Pfam	PF00850. Hist_deacetyl. 1 hit. [Graphical view]
PIRSF	PIRSF037913. His_deacetylse_1. 1 hit.
PRINTS	PR01270. HDASUPER. PR01271. HISDACETLASE.
ProtoNet	Search...

Entry information

Entry name

B0X1P4_CULQU

Accession

Primary (citable) accession number: B0X1P4

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	April 3, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)