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Protein
Submitted name:

Poly(A) polymerase beta

Gene

6046023

Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions. Also active with manganese.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi38Magnesium 1; catalyticUniRule annotation1
Metal bindingi38Magnesium 2; catalyticUniRule annotation1
Metal bindingi90Magnesium 2; catalyticUniRule annotation1
Binding sitei90ATPUniRule annotation1
Binding sitei151ATPUniRule annotation1
Binding sitei160ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi169 – 170ATPUniRule annotation2

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingUniRule annotation, MagnesiumUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Poly(A) polymerase betaImported
Gene namesi
Name:6046023Imported
ORF Names:CpipJ_CPIJ012940Imported
OrganismiCulex quinquefasciatus (Southern house mosquito) (Culex pungens)Imported
Taxonomic identifieri7176 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeCulicinaeCuliciniCulexCulex
Proteomesi
  • UP000002320 Componenti: Partially assembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi7176.CPIJ012940-PA

Structurei

3D structure databases

ProteinModelPortaliB0X0X1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 186PAP_centralInterPro annotationAdd BLAST108
Domaini187 – 266PAP_centralInterPro annotationAdd BLAST80
Domaini269 – 343PAP_RNA-bindInterPro annotationAdd BLAST75

Phylogenomic databases

eggNOGiKOG2245 Eukaryota
COG5186 LUCA
HOGENOMiHOG000204376
InParanoidiB0X0X1
KOiK14376
OMAiICHICPT
OrthoDBiEOG091G0571
PhylomeDBiB0X0X1

Family and domain databases

InterProiView protein in InterPro
IPR011068 NuclTrfase_I-like_C
IPR007012 PolA_pol_cen_dom
IPR007010 PolA_pol_RNA-bd_dom
IPR014492 PolyA_polymerase
PANTHERiPTHR10682 PTHR10682, 3 hits
PfamiView protein in Pfam
PF04928 PAP_central, 2 hits
PF04926 PAP_RNA-bind, 1 hit
PIRSFiPIRSF018425 PolyA_polymerase, 2 hits
SUPFAMiSSF55003 SSF55003, 1 hit

Sequencei

Sequence statusi: Complete.

B0X0X1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCPSRRTCRK CWQRSSAERS TLLGRTGWPL TTILTNIDAL CVAPRNIERQ
60 70 80 90 100
DYFGSFLELL EKQPEVTECR AVEEMLVPDV KMNFDGIKID LLFARLALKE
110 120 130 140 150
IPDNFDLRED MLLKNLDPKL MRSLNGCRAT DEILRLVPNI DNFRLALRST
160 170 180 190 200
KLWAKKHGIY STSLGYFGGV SWAMLVARTC QLPNVVPVFL KRPDTVNLGF
210 220 230 240 250
QVWDPRVNVQ GRFDLMPIIT PAYPQQNSTF HVSSSTRKIM LNEFNRGMQI
260 270 280 290 300
TDEIMLGKAG WDKLFEAPSF FFKYRYFIVL LVTSNNTDDL LEWCGLVESK
310 320 330 340 350
IRYLIQNLER ILHINLAHVH IKVLETTRDG MKTEARHVRR KQLNQYLDPN
360 370
LLKRERKNQR LLRRRKCAND LLRRN
Length:375
Mass (Da):43,802
Last modified:April 8, 2008 - v1
Checksum:iB84940CCAF9F7F64
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS232247 Genomic DNA Translation: EDS38363.1
RefSeqiXP_001863293.1, XM_001863258.1

Genome annotation databases

EnsemblMetazoaiCPIJ012940-RA; CPIJ012940-PA; CPIJ012940
GeneIDi6046023
KEGGicqu:CpipJ_CPIJ012940
VectorBaseiCPIJ012940-RA; CPIJ012940-PA; CPIJ012940

Entry informationi

Entry nameiB0X0X1_CULQU
AccessioniPrimary (citable) accession number: B0X0X1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: March 28, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health