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Protein

Moesin/ezrin/radixin homolog 1

Gene

Moe

Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in connections of major cytoskeletal structures to the plasma membrane.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Moesin/ezrin/radixin homolog 1By similarity
Gene namesi
Name:MoeBy similarity
ORF Names:CPIJ012259
OrganismiCulex quinquefasciatus (Southern house mosquito) (Culex pungens)
Taxonomic identifieri7176 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeCulicinaeCuliciniCulexCulex
Proteomesi
  • UP000002320 Componenti: Partially assembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell junction, Cell membrane, Cytoplasm, Cytoskeleton, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003550941 – 572Moesin/ezrin/radixin homolog 1Add BLAST572

Proteomic databases

PRIDEiB0WYY2

Interactioni

Subunit structurei

Interacts with cytoskeletal actin.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7176.CPIJ012259-PA

Structurei

3D structure databases

ProteinModelPortaliB0WYY2
SMRiB0WYY2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 291FERMPROSITE-ProRule annotationAdd BLAST291

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi307 – 480Glu-richSequence analysisAdd BLAST174

Phylogenomic databases

eggNOGiKOG3529 Eukaryota
ENOG410XQFP LUCA
HOGENOMiHOG000007113
InParanoidiB0WYY2
OMAiTMKAQKE
OrthoDBiEOG091G06UO
PhylomeDBiB0WYY2

Family and domain databases

CDDicd14473 FERM_B-lobe, 1 hit
Gene3Di1.20.80.10, 1 hit
1.25.40.1020, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR019749 Band_41_domain
IPR011174 ERM
IPR011259 ERM_C_dom
IPR000798 Ez/rad/moesin-like
IPR014352 FERM/acyl-CoA-bd_prot_sf
IPR035963 FERM_2
IPR019748 FERM_central
IPR019747 FERM_CS
IPR000299 FERM_domain
IPR018979 FERM_N
IPR018980 FERM_PH-like_C
IPR008954 Moesin_tail_sf
IPR011993 PH-like_dom_sf
IPR029071 Ubiquitin-like_domsf
PfamiView protein in Pfam
PF00769 ERM, 1 hit
PF09380 FERM_C, 1 hit
PF00373 FERM_M, 1 hit
PF09379 FERM_N, 1 hit
PIRSFiPIRSF002305 ERM, 1 hit
PRINTSiPR00935 BAND41
PR00661 ERMFAMILY
SMARTiView protein in SMART
SM00295 B41, 1 hit
SM01196 FERM_C, 1 hit
SUPFAMiSSF47031 SSF47031, 1 hit
SSF48678 SSF48678, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS00660 FERM_1, 1 hit
PS00661 FERM_2, 1 hit
PS50057 FERM_3, 1 hit

Sequencei

Sequence statusi: Complete.

B0WYY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVRVTTMDA ELEFAIQQST TGKQLFDQVV KTIGLREVWF FGLQYTDSKG
60 70 80 90 100
DLTWIKLYKK VMSQDVQKGD PLQFKFRAKF YPEDVAEELI QDITLRLFYL
110 120 130 140 150
QVKNAILSDE IYCPPETSVL LASYAVQARH GDYNKTTHTP GFLVNDRLLP
160 170 180 190 200
QRVIDQHKMS KDEWENSITT WWQEHRGMLR EDAMMEYLKI AQDLEMYGVN
210 220 230 240 250
YFEIRNKKGT ELWLGVDALG LNIYEKDDRL TPKIGFPWSE IRNISFNDRK
260 270 280 290 300
FIIKPIDKKA PDFVFFAPRV RINKRILALC MGNHELYMRR RKPDTIDVQQ
310 320 330 340 350
MKAQAREEKN AKQQEREKLQ LALAARERAE KKQQEYEDRI RNMQEEMERS
360 370 380 390 400
QANLIEAQDM IRRLEEQLKQ LQAAKDDLEQ RQNELQVMIT RLEETKNMEA
410 420 430 440 450
AERAKLEDEI RMKQEEVHKI QEEVSVKDSE TKRLQEEVEE ARRKQTEAAA
460 470 480 490 500
ALLAATTTPS HHHVEEEEEM DNEEELVNGE NGNQDFSKDF DTDEHIKDPV
510 520 530 540 550
EERRTLAERN ERLHDQLKAL KQDLALSRDD TMETANDKIH RENVRQGRDK
560 570
YKTLREIRKG NTKRRVDQFE NM
Length:572
Mass (Da):67,748
Last modified:April 8, 2008 - v1
Checksum:iC677CBEE39EA0085
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS232201 Genomic DNA Translation: EDS37245.1
RefSeqiXP_001862607.1, XM_001862572.1
UniGeneiCpi.3387

Genome annotation databases

EnsemblMetazoaiCPIJ012259-RA; CPIJ012259-PA; CPIJ012259
GeneIDi6045211
KEGGicqu:CpipJ_CPIJ012259
VectorBaseiCPIJ012259-RA; CPIJ012259-PA; CPIJ012259

Similar proteinsi

Entry informationi

Entry nameiMOEH_CULQU
AccessioniPrimary (citable) accession number: B0WYY2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: April 8, 2008
Last modified: March 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health