ATP-dependent RNA helicase DHX8 - Culex quinquefasciatus (Southern house mosquito)

Preferred order of sections

Names and origin

Protein names

Submitted name:
ATP-dependent RNA helicase DHX8 EMBL EDS35805.1

Gene names

ORF Names:

CpipJ_CPIJ011263 EMBL EDS35805.1

Organism

Culex quinquefasciatus (Southern house mosquito) (Culex pungens) [Complete proteome]

Taxonomic identifier

7176 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Culicini › Culex › Culex ›

Protein attributes

Sequence length	1253 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 helicase ATP-binding domain. SAAS SAAS007502

Contains 1 helicase C-terminal domain. SAAS SAAS007502

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Helicase RuleBase RU000452 EMBL EDS35805.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent helicase activity Inferred from electronic annotation. Source: InterPro RNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

B0WVX3 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 4410056223A869D4
Show »

FASTA

1,253

142,589

        10         20         30         40         50         60 
MDELEQLEHL SLVSKICTEL ENHLGLNDKD LAEFIIDLAE KNPSEEGFRR VLGENGAEFS 

        70         80         90        100        110        120 
ESFTANLLRI IQLMKPPKNR PGGGGAADFE RDDQVGALAC KFPGLAIPNA KKGYESEPED 

       130        140        150        160        170        180 
GEEFESKKRT NVVDDMFAEL ESMAPSTSKG GGSKKSREQQ EVDNMLAELE SLAPSTSSTG 

       190        200        210        220        230        240 
KREDREGGRL DRRSRSKDRK RSRSRERKRS RSRDRDRERR RRSRSRDKER RRRSRSGERD 

       250        260        270        280        290        300 
RRSRRSRSRS RDRRRHRSRS REFEQRKRTP PRQMPEEPEP GQIYNGRVVN IVAFGCFVQL 

       310        320        330        340        350        360 
TDFRRKKEGL VHISQLSSEG RVNTVTDVVN RNDNVKVKVI SIAGSKISLC MKDVDQESGK 

       370        380        390        400        410        420 
DLNPLSHAHL QDGEMANRNP DRPMNVPSML NIQENDGAEE TSHKKVTRIS SPERWEIKQM 

       430        440        450        460        470        480 
ISSGVIDRSE MPDFDEETGL LPKDEDSEAD IEIEIVEDEP PFLQGHGRAL HDLSPVRIVK 

       490        500        510        520        530        540 
NPDGSLAQAA MMQSALAKER REVKMLQREQ EMDSVPTNMN KNWIDPLPEE DTRALAANVR 

       550        560        570        580        590        600 
GVGMAMADVP EWKKAIIGGK KSSYGKKTDM SLVEQRQSLP IYKLRDDLIK AVTDNQILIV 

       610        620        630        640        650        660 
IGETGSGKTT QITQYLAECG FIARGKIGCT QPRRVAAMSV AKRVAEEYGC RLGQEVGYTI 

       670        680        690        700        710        720 
RFEDCTSQET VIKYMTDGML LRECLVDFDL KSYSVIMLDE AHERTIHTDV LFGLLKQAVQ 

       730        740        750        760        770        780 
KRPELKLIVT SATLDAVKFS QYFFEAPIFT IPGRTFPVEI LYTKEPETDY LDASLITVGY 

       790        800        810        820        830        840 
YCGNYDAKLS SYLFQVMQIH LREPPGDILL FLTGQEEIDT ACEILYERMK SLGPDVPELI 

       850        860        870        880        890        900 
ILPVYSALPS EMQTRIFDPA PPGSRKVVIA TNIAETSLTI DGIYYVVDPG FVKQKVYNSK 

       910        920        930        940        950        960 
TGMDSLVVTP ISQAAAKQRA GRAGRTGPGK AYRLYTERAY RDEMLPTPVP EIQRTNLATT 

       970        980        990       1000       1010       1020 
VLQLKTMGIN DLLHFDFMDA PPVESLVMAL EQLHSLSALD NEGLLTRLGR RMAEFPLEPN 

      1030       1040       1050       1060       1070       1080 
LSKLLIMSVA LNCSDEVLTI VSMISVQNVF YRPKDKQALA DQKKAKFNQI EGDHLTLLAV 

      1090       1100       1110       1120       1130       1140 
YNSWKNNKFS NAWCYENFVQ IRTLKRAQDV RKQLLGIMDR HKLDVVSAGK STMRVQKAIC 

      1150       1160       1170       1180       1190       1200 
SGFFRNAAKK DPQEGYRTLV DSQVVYIHPS SALFNRQPEW VVYHELVQTT KEYMREVTTI 

      1210       1220       1230       1240       1250 
DPKWLVEFAP AFFRFSDPTK LSKFKKNQRL EPLYNKYEEP NAWRISRTRR RRN

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References

[1]

"Annotation of Culex pipiens quinquefasciatus."
The Broad Institute Genome Sequencing Platform
Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D., Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P., Antoine C.H.

Collins F.H.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JHB.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS232134 Genomic DNA. Translation: EDS35805.1.
RefSeq	XP_001861545.1. XM_001861510.1.
3D structure databases
ProteinModelPortal	B0WVX3.
SMR	B0WVX3. Positions 276-364.
ModBase	Search...
Protein-protein interaction databases
STRING	7176.CPIJ011263-PA.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	CPIJ011263-RA; CPIJ011263-PA; CPIJ011263.
GeneID	6043961.
KEGG	cqu:CpipJ_CPIJ011263.
VectorBase	CPIJ011263. Culex quinquefasciatus.
Phylogenomic databases
eggNOG	COG1643.
HOGENOM	HOG000175261.
KO	K12818.
OMA	NAWCYEN.
OrthoDB	EOG437PVS.
PhylomeDB	B0WVX3.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
InterPro	IPR011545. DNA/RNA_helicase_DEAD/DEAH_N. IPR002464. DNA/RNA_helicase_DEAH_CS. IPR011709. DUF1605. IPR013957. DUF1777. IPR007502. Helicase-assoc_dom. IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. IPR012340. NA-bd_OB-fold. IPR027417. P-loop_NTPase. IPR003029. Rbsml_prot_S1_RNA-bd_dom. IPR022967. RNA-binding_domain_S1. [Graphical view]
Pfam	PF00270. DEAD. 1 hit. PF08648. DUF1777. 1 hit. PF04408. HA2. 1 hit. PF00271. Helicase_C. 1 hit. PF07717. OB_NTP_bind. 1 hit. PF00575. S1. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00847. HA2. 1 hit. SM00490. HELICc. 1 hit. SM00316. S1. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF52540. SSF52540. 1 hit.
PROSITE	PS00690. DEAH_ATP_HELICASE. 1 hit. PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. PS50126. S1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B0WVX3_CULQU

Accession

Primary (citable) accession number: B0WVX3

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	May 29, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry information