B0WAM5 (EIF3E_CULQU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Eukaryotic translation initiation factor 3 subunit E
Short name=eIF3e

Alternative name(s):
Eukaryotic translation initiation factor 3 subunit 6

Gene names

Name:	eIF3-S6
ORF Names:	CPIJ003936

Organism

Culex quinquefasciatus (Southern house mosquito) (Culex pungens) [Complete proteome]

Taxonomic identifier

7176 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Culicoidea › Culicidae › Culicinae › Culicini › Culex › Culex › Culex pipiens complex

Protein attributes

Sequence length	435 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity. HAMAP-Rule MF_03004
Subunit structure	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the eIF-3 subunit E family. Contains 1 PCI domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 435	435	Eukaryotic translation initiation factor 3 subunit E HAMAP-Rule MF_03004		PRO_0000365962
Regions
	Domain	284 – 389	106	PCI

Sequences

	Sequence		Length	Mass (Da)
	B0WAM5 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 35825B993A91A9E6	FASTA	435	51,173
	10 20 30 40 50 60 MSKFDLTAKN CQYLDRHLTF PLLEFLLQKN IYDQTSLLKF ILETVSKTNM VDYTMDIRER 70 80 90 100 110 120 LNMGNELPEE LTKRRSNVLV KLKELQTEVA PLMKCMEELK NPDTMKDSKS IVHALQQEFD 130 140 150 160 170 180 FKYDIIRSAQ KLAKYLYECG NYRDSISYLY ICLLVMEPTD KNYLNVLWGK LAAEILTLNW 190 200 210 220 230 240 PTALEDLTRL RDFIDNHNFS PIEVLQQRTW LIHWSVLVFF NHAKGRDLII EMFLYKQLYL 250 260 270 280 290 300 NAIQTMCPHI LRYLATAVII NRGRRNALKD LIKIIQQESY TYKDPITEFL ECLYVNFDFE 310 320 330 340 350 360 GARMKLHECQ TVIINDFFII GCLQEFIENA RLMIFETFCR IHQCITIGML ADKLNMEPDE 370 380 390 400 410 420 AECWIVNLIR NARLDAKIDS KLGHVVMGTQ PLSPYQQLVE KIDSLSVRSE ALTVLVERKQ 430 KAKTQESGEG NWKYY

References

[1]

"Annotation of Culex pipiens quinquefasciatus." The Broad Institute Genome Sequencing Platform Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D., Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P., Antoine C.H. , Arensburger P., Bidwell S.L., Crawford M., Camaro F., Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D., Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J., Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E., Fraser-Liggett C.M., Strausberg R., Galagan J., Birren B., Collins F.H. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JHB.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS231873 Genomic DNA. Translation: EDS41579.1.
RefSeq	XP_001845759.1. XM_001845707.1.
UniGene	Cpi.4637.
3D structure databases
ProteinModelPortal	B0WAM5.
ModBase	Search...
Protein-protein interaction databases
STRING	7176.CPIJ003936-PA.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	CPIJ003936-RA; CPIJ003936-PA; CPIJ003936.
GeneID	6035610.
KEGG	cqu:CpipJ_CPIJ003936.
VectorBase	CPIJ003936. Culex quinquefasciatus.
Phylogenomic databases
eggNOG	NOG324642.
HOGENOM	HOG000036697.
KO	K03250.
OMA	FLEHLYV.
OrthoDB	EOG4HQC0M.
PhylomeDB	B0WAM5.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
HAMAP	MF_03004. eIF3e.
InterPro	IPR019010. eIF3_su6_N. IPR000717. PCI_dom. IPR016650. Transl_init_fac_3_su6_euk. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF09440. eIF3_N. 1 hit. PF01399. PCI. 1 hit. [Graphical view]
PIRSF	PIRSF016255. eIF3e_su6. 1 hit.
SMART	SM00088. PINT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EIF3E_CULQU

Accession

Primary (citable) accession number: B0WAM5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	April 8, 2008
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)