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Protein

Eukaryotic translation initiation factor 3 subunit E

Gene

eIF3-S6

Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 3 subunit EUniRule annotation
Short name:
eIF3eUniRule annotation
Alternative name(s):
Eukaryotic translation initiation factor 3 subunit 6UniRule annotation
Gene namesi
Name:eIF3-S6
ORF Names:CPIJ003936
OrganismiCulex quinquefasciatus (Southern house mosquito) (Culex pungens)
Taxonomic identifieri7176 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeCuliciniCulexCulex
ProteomesiUP000002320 Componenti: Partially assembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 435435Eukaryotic translation initiation factor 3 subunit EPRO_0000365962Add
BLAST

Interactioni

Subunit structurei

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.UniRule annotation

Protein-protein interaction databases

STRINGi7176.CPIJ003936-PA.

Structurei

3D structure databases

ProteinModelPortaliB0WAM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini284 – 389106PCIUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the eIF-3 subunit E family.UniRule annotation
Contains 1 PCI domain.UniRule annotation

Phylogenomic databases

eggNOGiNOG324642.
HOGENOMiHOG000036697.
InParanoidiB0WAM5.
KOiK03250.
OMAiKGTNMVD.
OrthoDBiEOG7QNVKP.
PhylomeDBiB0WAM5.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_03004. eIF3e.
InterProiIPR016650. eIF3e.
IPR019010. eIF3e_N.
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR10317. PTHR10317. 1 hit.
PfamiPF09440. eIF3_N. 1 hit.
PF01399. PCI. 1 hit.
[Graphical view]
PIRSFiPIRSF016255. eIF3e_su6. 1 hit.
SMARTiSM00088. PINT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0WAM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKFDLTAKN CQYLDRHLTF PLLEFLLQKN IYDQTSLLKF ILETVSKTNM
60 70 80 90 100
VDYTMDIRER LNMGNELPEE LTKRRSNVLV KLKELQTEVA PLMKCMEELK
110 120 130 140 150
NPDTMKDSKS IVHALQQEFD FKYDIIRSAQ KLAKYLYECG NYRDSISYLY
160 170 180 190 200
ICLLVMEPTD KNYLNVLWGK LAAEILTLNW PTALEDLTRL RDFIDNHNFS
210 220 230 240 250
PIEVLQQRTW LIHWSVLVFF NHAKGRDLII EMFLYKQLYL NAIQTMCPHI
260 270 280 290 300
LRYLATAVII NRGRRNALKD LIKIIQQESY TYKDPITEFL ECLYVNFDFE
310 320 330 340 350
GARMKLHECQ TVIINDFFII GCLQEFIENA RLMIFETFCR IHQCITIGML
360 370 380 390 400
ADKLNMEPDE AECWIVNLIR NARLDAKIDS KLGHVVMGTQ PLSPYQQLVE
410 420 430
KIDSLSVRSE ALTVLVERKQ KAKTQESGEG NWKYY
Length:435
Mass (Da):51,173
Last modified:April 8, 2008 - v1
Checksum:i35825B993A91A9E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS231873 Genomic DNA. Translation: EDS41579.1.
RefSeqiXP_001845759.1. XM_001845707.1.
UniGeneiCpi.4637.

Genome annotation databases

EnsemblMetazoaiCPIJ003936-RA; CPIJ003936-PA; CPIJ003936.
GeneIDi6035610.
KEGGicqu:CpipJ_CPIJ003936.
VectorBaseiCPIJ003936. Culex quinquefasciatus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS231873 Genomic DNA. Translation: EDS41579.1.
RefSeqiXP_001845759.1. XM_001845707.1.
UniGeneiCpi.4637.

3D structure databases

ProteinModelPortaliB0WAM5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7176.CPIJ003936-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiCPIJ003936-RA; CPIJ003936-PA; CPIJ003936.
GeneIDi6035610.
KEGGicqu:CpipJ_CPIJ003936.
VectorBaseiCPIJ003936. Culex quinquefasciatus.

Phylogenomic databases

eggNOGiNOG324642.
HOGENOMiHOG000036697.
InParanoidiB0WAM5.
KOiK03250.
OMAiKGTNMVD.
OrthoDBiEOG7QNVKP.
PhylomeDBiB0WAM5.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_03004. eIF3e.
InterProiIPR016650. eIF3e.
IPR019010. eIF3e_N.
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR10317. PTHR10317. 1 hit.
PfamiPF09440. eIF3_N. 1 hit.
PF01399. PCI. 1 hit.
[Graphical view]
PIRSFiPIRSF016255. eIF3e_su6. 1 hit.
SMARTiSM00088. PINT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JHB.

Entry informationi

Entry nameiEIF3E_CULQU
AccessioniPrimary (citable) accession number: B0WAM5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: April 8, 2008
Last modified: May 27, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.