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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

CpipJ_CPIJ000232

Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei206 – 2061Proton acceptorUniRule annotation

GO - Molecular functioni

  1. glycerol-3-phosphate dehydrogenase [NAD+] activity Source: UniProtKB-EC
  2. NAD binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. glycerol-3-phosphate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:CpipJ_CPIJ000232Imported
OrganismiCulex quinquefasciatus (Southern house mosquito) (Culex pungens)Imported
Taxonomic identifieri7176 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeCuliciniCulexCulex
ProteomesiUP000002320 Componenti: Partially assembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7176.CPIJ000232-PA.

Structurei

3D structure databases

ProteinModelPortaliB0VZW3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni270 – 2712Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0240.
HOGENOMiHOG000246855.
InParanoidiB0VZW3.
KOiK00006.
OMAiEVANDNF.
OrthoDBiEOG7ZKSBS.
PhylomeDBiB0VZW3.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.

Sequencei

Sequence statusi: Complete.

B0VZW3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADKVKVCIV GSGNWGSAIA KIVGVNAKRL PTFEDRVTMY VFEEQVDGKK
60 70 80 90 100
LTEIINSTHE NVKYLPGHKL PENIVAVPDV VEAAKDADIL IFVVPHQFIR
110 120 130 140 150
GLGQQLLGKI KKTAVGLSLI KGFDVAEGGG MELISHLITK HLNIPCNVLM
160 170 180 190 200
GANLANEVAE EKFCETTIGC RDMKVAQTFR DLFQTPNFRV VVVDDVDAVE
210 220 230 240 250
ICGALKNIVA CGAGFVDGMG GGDNTKAAVI RLGLMEMIKF VDVFYPGSKL
260 270 280 290 300
STFFESCGVA DLITTCYGGR NRKVSEAFVK TGKSIKQLED EMLNGQKLQG
310 320 330 340 350
PITAEEVNFM LKSKSMEDKF PLFTAIHKIC TGQIKPAGFL DCLRNHPEHM

QTFS
Length:354
Mass (Da):38,647
Last modified:April 8, 2008 - v1
Checksum:i249BA5AC95709E0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS231815 Genomic DNA. Translation: EDS35205.1.
RefSeqiXP_001841997.1. XM_001841945.1.
UniGeneiCpi.3956.

Genome annotation databases

EnsemblMetazoaiCPIJ000232-RA; CPIJ000232-PA; CPIJ000232.
GeneIDi6031154.
KEGGicqu:CpipJ_CPIJ000232.
VectorBaseiCPIJ000232. Culex quinquefasciatus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS231815 Genomic DNA. Translation: EDS35205.1.
RefSeqiXP_001841997.1. XM_001841945.1.
UniGeneiCpi.3956.

3D structure databases

ProteinModelPortaliB0VZW3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7176.CPIJ000232-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiCPIJ000232-RA; CPIJ000232-PA; CPIJ000232.
GeneIDi6031154.
KEGGicqu:CpipJ_CPIJ000232.
VectorBaseiCPIJ000232. Culex quinquefasciatus.

Phylogenomic databases

eggNOGiCOG0240.
HOGENOMiHOG000246855.
InParanoidiB0VZW3.
KOiK00006.
OMAiEVANDNF.
OrthoDBiEOG7ZKSBS.
PhylomeDBiB0VZW3.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JHBImported.

Entry informationi

Entry nameiB0VZW3_CULQU
AccessioniPrimary (citable) accession number: B0VZW3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: April 29, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.